Celiac Disease, Susceptibility To, 1; Celiac1

Description

Celiac disease, also known as celiac sprue and gluten-sensitive enteropathy (GSE), is a multifactorial disorder of the small intestine that is influenced by both environmental and genetic factors. It is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine after the ingestion of wheat gluten or related rye and barley proteins (summary by Farrell and Kelly, 2002). Long regarded as gastrointestinal disorder of childhood, the disease is now considered to be a chronic systemic autoimmune disease and is more often diagnosed in adults than in children (Monsuur et al., 2005).For a discussion of genetic heterogeneity of celiac disease, see MAPPING.

Clinical Features

Top most frequent phenotypes and symptoms related to Celiac Disease, Susceptibility To, 1; Celiac1

  • Seizures
  • Short stature
  • Ataxia
  • Failure to thrive
  • Anemia
  • Fatigue
  • Vomiting
  • Diarrhea
  • Depressivity
  • Alopecia

And another 45 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Celiac Disease, Susceptibility To, 1; Celiac1 Is also known as celiac sprue, susceptibility to, 1, gluten-sensitive enteropathy, susceptibility to, 1.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Celiac Disease, Susceptibility To, 1; Celiac1 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Narcolepsy (HLA-DQB1 06:02) Genotyping.

By ARUP Laboratories, Molecular Genetics and Genomics (United States).

HLA-DQB1
Specificity
100 %
Genes
50 %
Celiac Disease (HLA-DQ2 and HLA-DQ8) Genotyping.

By ARUP Laboratories, Molecular Genetics and Genomics (United States).

HLA-DQA1, HLA-DQB1
Specificity
100 %
Genes
100 %
Celiac disease (HLA-DQ/DR).

By CGC Genetics (Portugal).

HLA-DQA1, HLA-DQB1
Specificity
100 %
Genes
100 %
Lactose intolerance (MCM6 gene) and Celiac disease (HLA-DQ2/ HLA-DQ8).

By CGC Genetics (Portugal).

HLA-DQA1, HLA-DQB1, MCM6
Specificity
67 %
Genes
100 %
Celiac Disease via Next Generation Sequencing HLA Typing.

By PreventionGenetics PreventionGenetics (United States).

HLA-DQA1, HLA-DQB1
Specificity
100 %
Genes
100 %
Narcolepsy Risk Factor.

By Bioscientia GmbH Center for Human Genetics (Germany).

HLA-DQB1, HLA-DRB1
Specificity
50 %
Genes
50 %
HLA DQ2/DQ8.

By Furst Medical Laboratories, FurstNAT (Norway).

HLA-DQA1, HLA-DQB1
Specificity
100 %
Genes
100 %
Celiac Disease (HLA-DQA1*05, HLA-DQB1*02, and HLA-DQB1*03:02) Genotyping.

By Molecular Genetics Laboratory Centro de Investigaciones Endocrinologicas "Dr. Cesar Bergada" (Argentina).

HLA-DQA1, HLA-DQB1
Specificity
100 %
Genes
100 %

We have 2 more panels available in our App

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Sources and references

You can check the following sources for additional information.

OMIM Genetic Syndrome Finder

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