Atrial Fibrillation, Familial, 11; Atfb11

Description

Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997).For a discussion of genetic heterogeneity of familial atrial fibrillation, see ATFB1 (OMIM ).

Clinical Features

Phenotypes and symptoms related to Atrial Fibrillation, Familial, 11; Atfb11

  • Stroke
  • Atrial fibrillation
  • Thromboembolic stroke

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Atrial Fibrillation, Familial, 11; Atfb11 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Atrial Fibrillation Panel.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States).

SCN1B, SCN2B, SCN5A, SCN3B, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE2, KCNH2, KCNJ2, KCNQ1, LMNA, NPPA, NUP155
Specificity
7 %
Genes
100 %
GJA5.

By Institute for Human Genetics University Clinic Freiburg (Germany).

GJA5
Specificity
100 %
Genes
100 %
Cardiac Arrhythmia NGS Multi-Gene Panel (48 genes), Sequence & CNV analysis.

By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam (Netherlands).

RYR2, SCN10A, SCN1B, SCN2B, SCN4B, SCN5A, SNTA1, TNNT2, TRDN, CACNA1C, CACNA1D, CACNA2D1, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, SLMAP, HCN4 , (...)

View the complete list with 27 more genes
Specificity
3 %
Genes
100 %
Atrial fibrillation, familial 11 (sequence analysis of GJA5 gene).

By CGC Genetics (Portugal).

GJA5
Specificity
100 %
Genes
100 %
Familial Atrial Fibrillation Syndrome Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

SCN1B, SCN2B, SCN5A, SCN3B, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE5, KCNE2, KCNH2, KCNJ2, KCNQ1, NPPA
Specificity
7 %
Genes
100 %
Atrial Fibrillation via GJA5 Gene Sequencing with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

GJA5
Specificity
100 %
Genes
100 %
Comprehensive Cardiology Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

RYR1, RYR2, SCN1B, SCN2B, SCN4B, SCN5A, SCO2, SGCD, SGCG, BRAF, SLC25A4, SNTA1, SOS1, SREBF2, TAZ, TBX3, TBX5, TCAP, TGFB2, TGFB3 , (...)

View the complete list with 143 more genes
Specificity
1 %
Genes
100 %
Comprehensive Cardiac Arrhythmia Sequencing Panel with CNV Detection.

By PreventionGenetics PreventionGenetics (United States).

RYR2, SCN10A, SCN1B, SCN2B, SCN4B, SCN5A, SNTA1, TGFB3, TNNI3, TRDN, CACNA1C, CACNA2D1, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, LDB3, SLMAP , (...)

View the complete list with 35 more genes
Specificity
2 %
Genes
100 %

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Sources and references

You can check the following sources for additional information.

OMIM Genetic Syndrome Finder

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