Aplasia Of Lacrimal And Salivary Glands
Description
Aplasia of the lacrimal and salivary glands (ALSG) is a rare autosomal dominant disorder characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary glands leading to varying features since infancy such as recurrent eye infections, irritable eyes, epiphora, xerostomia, dental caries, dental erosion and oral inflammation.
Incidence and onset information
— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)— No data available about the known clinical features onset.
Alternative names
Aplasia Of Lacrimal And Salivary Glands Is also known as congenital absence of lacrimal puncta and salivary glands, alsg.
Researches and researchers
Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.Aplasia Of Lacrimal And Salivary Glands Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
![]() By Center for Human Genetics, Inc (United States).
FGF10
Specificity
100 %
Genes
100 % |
![]() By Genetic Services Laboratory University of Chicago (United States).
SALL1, BMP4, SOX2, SRD5A2, HNF1B, MED12, WNT7A, WT1, FBXL4, ZEB2, SETBP1, TP63, PCNT, UBR1, FIG4, CDKN1C, ARX, GRIP1, FRAS1, EVC2 , (...)
View the complete list with 41 more genes
Specificity
2 %
Genes
100 % |
![]() By CGC Genetics (Portugal).
FGF10
Specificity
100 %
Genes
100 % |
![]() By CGC Genetics (Portugal).
FGF10
Specificity
100 %
Genes
100 % |
![]() By CGC Genetics (Portugal).
FGF10
Specificity
100 %
Genes
100 % |
![]() By PreventionGenetics PreventionGenetics (United States).
SALL1, BMP4, BMP7, SOX2, SRD5A2, HNF1B, MED12, WNT7A, WT1, FBXL4, WDR11, ZEB2, SETBP1, TP63, PCNT, ZFPM2, UBR1, FIG4, CDKN1C, ARX , (...)
View the complete list with 53 more genes
Specificity
2 %
Genes
100 % |
![]() By PreventionGenetics PreventionGenetics (United States).
ROR2, SALL1, BMP2, BMPR1B, SF3B4, FBXW4, SHH, BRCA2, SOX9, TBX15, TBX3, TBX5, THPO, WNT3, WNT7A, LMBR1, NSDHL, HDAC4, SALL4, TP63 , (...)
View the complete list with 48 more genes
Specificity
2 %
Genes
100 % |
![]() By PreventionGenetics PreventionGenetics (United States).
ROR2, SALL1, BMP15, BMP4, SEMA3A, SEMA3E, BMP7, FOXL2, BRDT, SOS1, SOX10, SOX2, SOX3, SOX9, SRA1, SRD5A2, SRY, STAG3, STAR, AURKC , (...)
View the complete list with 187 more genes
Specificity
1 %
Genes
100 % |
You can get up to 23 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
ORPHANET Rare Disease Search EngineIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like TREACHER-COLLINS SYNDROME SCHNECKENBECKEN DYSPLASIA; SHNKND GLYCOGEN STORAGE DISEASE Ib; GSD1B PEELING SKIN SYNDROME 2; PSS2 SPASTIC PARAPLEGIA 23; SPG23 ARTHROGRYPOSIS-OCULOMOTOR LIMITATION-ELECTRORETINAL ANOMALIES SYNDROME MYOTONIA CONGENITA, AUTOSOMAL RECESSIVE