Anterior Segment Dysgenesis 8; Asgd8


Anterior segment dysgeneses (ASGD or ASMD) are a heterogeneous group of developmental disorders affecting the anterior segment of the eye, including the cornea, iris, lens, trabecular meshwork, and Schlemm canal. The clinical features of ASGD include iris hypoplasia, an enlarged or reduced corneal diameter, corneal vascularization and opacity, posterior embryotoxon, corectopia, polycoria, an abnormal iridocorneal angle, ectopia lentis, and anterior synechiae between the iris and posterior corneal surface (summary by Cheong et al., 2016).

Clinical Features

Top most frequent phenotypes and symptoms related to Anterior Segment Dysgenesis 8; Asgd8

  • Cataract
  • Ectopia lentis
  • Ectropion
  • Posterior embryotoxon
  • Hypoplasia of the iris
  • Ectopia pupillae
  • Corneal neovascularization
  • Anterior segment developmental abnormality
  • Anterior synechiae of the anterior chamber
  • Polycoria

And another 6 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

Not enough data available about incidence and published cases.
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Anterior Segment Dysgenesis 8; Asgd8 Recommended genes panels

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Symptoms Checker

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