Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia; Als22

Clinical Features

Phenotypes and symptoms related to Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia; Als22

  • Dementia
  • Mental deterioration
  • Amyotrophic lateral sclerosis
  • Frontotemporal dementia
  • Abnormal lower motor neuron morphology

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia; Als22 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Frontotemporal dementia (NGS panel for 13 genes).

By CGC Genetics (Portugal).

TARDBP, TUBA4A, UBQLN2, VCP, CHCHD10, CSF1R, CHMP2B, FUS, GRN, HNRNPA1, HNRNPA2B1, MAPT, PSEN1
Specificity
8 %
Genes
100 %
Hereditary dementias (NGS panel for 28 genes).

By CGC Genetics (Portugal).

SNCA, SNCB, SORL1, TARDBP, TIMM8A, TUBA4A, TYROBP, UBQLN2, VCP, CHCHD10, TREM2, TRPM7, CSF1R, CHMP2B, DNMT1, ATP13A2, FUS, GRN, HNRNPA1, HNRNPA2B1 , (...)

View the complete list with 8 more genes
Specificity
4 %
Genes
100 %
Amyotrophic lateral sclerosis and related disorders Comprehensive panel.

By Connective Tissue Gene Tests (United States).

SOD1, SPG11, SQSTM1, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP, CHCHD10, FIG4, OPTN, CHMP2B, ARHGEF28, ERBB4, FUS, ALS2, SETX, ANG, HNRNPA1 , (...)

View the complete list with 4 more genes
Specificity
5 %
Genes
100 %
Amyotrophic lateral sclerosis and related disorders Deletion/ Duplication panel.

By Connective Tissue Gene Tests (United States).

SOD1, SPG11, SQSTM1, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP, CHCHD10, FIG4, OPTN, CHMP2B, ARHGEF28, ERBB4, FUS, ALS2, SETX, ANG, HNRNPA1 , (...)

View the complete list with 4 more genes
Specificity
5 %
Genes
100 %
Amyotrophic lateral sclerosis and related disorders NGS panel.

By Connective Tissue Gene Tests (United States).

SOD1, SPG11, SQSTM1, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP, CHCHD10, FIG4, OPTN, CHMP2B, ARHGEF28, ERBB4, FUS, ALS2, SETX, ANG, HNRNPA1 , (...)

View the complete list with 4 more genes
Specificity
5 %
Genes
100 %
AllNeuro panel.

By Centogene AG - the Rare Disease Company (Germany).

BCS1L, ROR2, RPL10, BDNF, RPS6KA3, RTN2, RYR1, SACS, BIN1, SBF1, SCN10A, SCN1A, SCN1B, SCN2A, SCN3A, SCN4A, SCN5A, SCN8A, SCN9A, SCO1 , (...)

View the complete list with 1177 more genes
Specificity
1 %
Genes
100 %
Amyotrophic Lateral Sclerosis (ALS) Panel.

By CeGaT GmbH (Germany).

ATXN1, ATXN2, SOD1, SPG11, SQSTM1, TAF15, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP, VEGFA, CHCHD10, SS18L1, PARK7, FIG4, SRCAP, OPTN, SPART , (...)

View the complete list with 33 more genes
Specificity
2 %
Genes
100 %
Frontotemporal Dementia (FTD) Panel.

By CeGaT GmbH (Germany).

ATXN2, SQSTM1, TARDBP, TBK1, TUBA4A, UBQLN2, VCP, CHCHD10, OPTN, TREM2, TOMM40, CSF1R, CHMP2B, DCTN1, C9orf72, FUS, GRN, HNRNPA1, HNRNPA2B1, ITM2B , (...)

View the complete list with 8 more genes
Specificity
4 %
Genes
100 %

You can get up to 6 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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