Amyotrophic Lateral Sclerosis 10 With Or Without Frontotemporal Dementia; Als10

Clinical Features

Top most frequent phenotypes and symptoms related to Amyotrophic Lateral Sclerosis 10 With Or Without Frontotemporal Dementia; Als10

  • Ataxia
  • Spasticity
  • Cognitive impairment
  • Dysarthria
  • Skeletal muscle atrophy
  • Gait disturbance
  • Dysphagia
  • Respiratory insufficiency
  • Edema
  • Congestive heart failure

And another 26 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

Not enough data available about incidence and published cases.
No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.


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Amyotrophic Lateral Sclerosis 10 With Or Without Frontotemporal Dementia; Als10 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Amyotrophic Lateral Sclerosis Advanced Evaluation.

By Athena Diagnostics Inc (United States).

SOD1, SQSTM1, TARDBP, UBQLN2, VAPB, VCP, FIG4, OPTN, CHMP2B, DCTN1, C9orf72, FUS, ALS2, SETX, ANG, SIGMAR1, PFN1
Specificity
6 %
Genes
100 %
Nonprevalent Amyotrophic Lateral Sclerosis Advanced Sequencing Evaluation.

By Athena Diagnostics Inc (United States).

SQSTM1, TARDBP, UBQLN2, VAPB, VCP, FIG4, OPTN, CHMP2B, DCTN1, FUS, ALS2, SETX, ANG, SIGMAR1, PFN1
Specificity
7 %
Genes
100 %
Amyotrophic Lateral Sclerosis.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

ATXN2, SOD1, TARDBP, UBQLN2, VAPB, VCP, VEGFA, FIG4, OPTN, SPART, CHMP2B, DCTN1, C9orf72, FUS, ALS2, SETX, ANG, NEFH, SIGMAR1, PFN1 , (...)

View the complete list with 1 more genes
Specificity
5 %
Genes
100 %
Dementia.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

SORL1, TARDBP, VCP, FIG4, OPTN, TREM2, CSF1R, CHMP2B, DCTN1, C9orf72, FUS, ALS2, SETX, GRN, ANG, APOE, APP, MAPT, PRNP, PSEN1 , (...)

View the complete list with 1 more genes
Specificity
5 %
Genes
100 %
Familial Amyotrophic Lateral Sclerosis 10.

By Sheffield Diagnostic Genetics Service Sheffield Children's NHS Foundation Trust (United Kingdom).

TARDBP
Specificity
100 %
Genes
100 %
TAR DNA binding protein TARDBP (TDP-43) gene sequencing test.

By Neurogenetics Department Cyprus Institute of Neurology and Genetics (Cyprus).

TARDBP
Specificity
100 %
Genes
100 %
TDP43. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

TARDBP
Specificity
100 %
Genes
100 %
TARDBP. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

TARDBP
Specificity
100 %
Genes
100 %

We have 63 more panels available in our App

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Sources and references

You can check the following sources for additional information.

OMIM MESH Rare Disease Search Engine

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