Abdominal Obesity-metabolic Syndrome 1; Aoms1

Description

A clustering of abdominal obesity, high triglycerides, low levels of high density lipoprotein cholesterol (HDLC), high blood pressure, and elevated fasting glucose levels is sometimes called metabolic syndrome X (Reaven, 1988) or abdominal obesity-metabolic syndrome (Bjorntorp, 1991). The syndrome may affect nearly 1 in 4 U.S. adults and is considered a veritable epidemic (Ford et al., 2002). It is a major risk factor for both diabetes mellitus (see {125853} and Haffner et al., 1992) and cardiovascular disease (Isomaa et al., 2001). The etiology is complex, determined by the interplay of both genetic and environmental factors. The prevalence varies substantially among ethnic groups, with the highest rates in Mexican American women (Park et al., 2003). Other factors influencing the metabolic syndrome include age, smoking, alcohol, diet, and physical inactivity. Genetic Heterogeneity of Abdominal Obesity-Metabolic SyndromeAOMS2 (OMIM ) has been mapped to chromosome 17p12. AOMS3 (OMIM ) is caused by mutation in the DYRK1B gene (OMIM ) on chromosome 19q13.

Clinical Features

Phenotypes and symptoms related to Abdominal Obesity-metabolic Syndrome 1; Aoms1

  • Hypertension
  • Obesity
  • Diabetes mellitus
  • Abnormality of the cardiovascular system
  • Abdominal obesity

Incidence and onset information

Not enough data available about incidence and published cases.
No data available about the known clinical features onset.

Alternative names

Abdominal Obesity-metabolic Syndrome 1; Aoms1 Is also known as metabolic syndrome x.

Researches and researchers

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Sources and references

You can check the following sources for additional information.

MESH OMIM Rare Disease Symptoms Checker

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