Atrial Fibrillation, Familial, 15; Atfb15

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Atrial fibrillation (AF) is a supraventricular tachyarrhythmia characterized by uncoordinated atrial activation with consequent deterioration of atrial mechanical function. It is the most common sustained cardiac rhythm disturbance, and its prevalence increases as the population ages. An estimated 70,000 strokes each year are caused by atrial fibrillation (summary by Oberti et al., 2004).For a discussion of genetic heterogeneity of atrial fibrillation, see {608583}.

Genes related to Atrial Fibrillation, Familial, 15; Atfb15

NUP155

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Clinical Features

Phenotypes and symptoms related to Atrial Fibrillation, Familial, 15; Atfb15

Cardiomyopathy
Abnormal heart morphology
Tachycardia
Atrial fibrillation
Supraventricular tachycardia
Atrial flutter

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Atrial Fibrillation, Familial, 15; Atfb15 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Atrial Fibrillation Panel. By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States). SCN1B, SCN2B, SCN5A, SCN3B, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE2, KCNH2, KCNJ2, KCNQ1, LMNA, NPPA, NUP155 Specificity 7 % Genes 100 %
Atrial Fibrillation NGS Panel. By Fulgent Genetics Fulgent Genetics (United States). RYR2, SCN1B, SCN2B, SCN4B, SCN5A, HCN4, SCN3B, GATA4, GATA6, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE2, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1 , (...) View the complete list with 3 more genes Panel complete gene list RYR2, SCN1B, SCN2B, SCN4B, SCN5A, HCN4, SCN3B, GATA4, GATA6, GJA5, ABCC9, KCNA5, KCND3, KCNE1, KCNE2, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1, LMNA, NPPA, NUP155 Specificity 5 % Genes 100 %
NUP155. By Fulgent Genetics Fulgent Genetics (United States). NUP155 Specificity 100 % Genes 100 %
Atrial Fibrillation Panel. By Blueprint Genetics (Finland). RYR2, SCN10A, SCN1B, SCN5A, TBX5, CACNB2, LDB3, HCN4, SCN3B, GATA6, KCNA5, KCNE1, KCNE2, KCNH2, KCNJ2, KCNJ5, KCNQ1, LMNA, NUP155 Specificity 6 % Genes 100 %
Arrhythmia Panel. By Blueprint Genetics (Finland). RYR2, SCN10A, SCN1B, SCN5A, TBX5, TGFB3, TNNI3, TNNT2, TRDN, TTN, CACNA1C, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, LDB3, SALL4, NOS1AP , (...) View the complete list with 35 more genes Panel complete gene list RYR2, SCN10A, SCN1B, SCN5A, TBX5, TGFB3, TNNI3, TNNT2, TRDN, TTN, CACNA1C, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, LDB3, SALL4, NOS1AP, HCN4, CDH2, TRPM4, TNNI3K, SCN3B, NKX2-5, CTNNA3, DBH, TECRL, DES, TMEM43, PPA2, DSC2, DSG2, DSP, AKAP9, GATA6, HADHA, ANK2, ABCC9, JUP, KCNA5, KCNE1, KCNE2, KCNH2, KCNJ2, KCNJ5, KCNQ1, LMNA, MYH6, MYL4, NUP155, PKP2, PLN, BAG3 Specificity 2 % Genes 100 %
Comprehensive Cardiology Panel. By Blueprint Genetics (Finland). RIT1, RRAS, RYR2, SCN10A, SCN1B, SCN5A, SCNN1B, SCNN1G, SCO2, SDHA, SGCA, SGCB, SGCD, SGCG, SLC22A5, BRAF, SLC25A4, SOS1, SOS2, TAZ , (...) View the complete list with 163 more genes Panel complete gene list RIT1, RRAS, RYR2, SCN10A, SCN1B, SCN5A, SCNN1B, SCNN1G, SCO2, SDHA, SGCA, SGCB, SGCD, SGCG, SLC22A5, BRAF, SLC25A4, SOS1, SOS2, TAZ, TBX20, TBX5, TCAP, TGFB3, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TSFM, MYOT, TTN, TTR, VCL, VCP, XK, ACTA1, ACTA2, GFM1, CACNA1C, CACNA2D1, PRDM16, CACNB2, ELAC2, JPH2, SLC25A20, ACTC1, CALM1, CALM2, CALM3, CAPN3, GTPBP3, CASQ2, CAV3, CBL, SHOC2, LDB3, GATA5, RBCK1, SALL4, SELENON, TRIM32, ACTN2, FBXO32, NOS1AP, HCN4, SPEG, TAB2, ALPK3, CDH2, TRPM4, FKRP, VPS13A, MTO1, TNNI3K, SPRED1, LRRC10, CALR3, SCN3B, AARS2, RMND1, ACAD9, AGK, COX15, GMPPB, MYPN, CPT2, DOLK, CRYAB, CSRP3, NKX2-5, CTNNA3, TMEM70, DBH, FOXRED1, ANO5, TECRL, RBM20, DES, NDUFAF2, TMEM43, PPA2, SMCHD1, PLEKHM2, DMD, EPG5, TOR1AIP1, NEXN, GATAD1, DSC2, DSG2, DSP, DNAJC19, DTNA, PNPLA2, DYSF, EEF1A2, AGL, EMD, ENPP1, ETFA, ETFB, ETFDH, FKTN, FHL1, ISPD, FLNC, AKAP9, FOXD4, FXN, GAA, GATA6, GBE1, ALMS1, GLA, GLB1, GUSB, HADHA, HAND1, HFE, ANK2, HRAS, ABCC6, ABCC9, JUP, KCNA5, KCNE1, KCNE2, KCNH2, KCNJ2, KCNJ5, KCNQ1, KRAS, LAMA2, LAMP2, LARGE1, LMNA, LZTR1, MAP2K1, MAP2K2, MLYCD, MYBPC3, MYH6, MYH7, MYL2, MYL3, MYL4, NF1, NRAS, NUP155, PCCA, PCCB, PKP2, PLEC, PLN, ACADVL, POMT1, PPP1CB, PRKAG2, BAG3, PTPN11, RAF1, RASA2 Specificity 1 % Genes 100 %
Familial Atrial Fibrillation , Panel Massive Sequencing (NGS) 13 Genes. By Reference Laboratory Genetics (Spain). SCN1B, SCN2B, SCN4B, SCN5A, SCN3B, GJA5, ABCC9, KCNA5, KCNE2, KCNJ2, KCNQ1, NPPA, NUP155 Specificity 8 % Genes 100 %
Cardiology Genetic Panel (Full) , Panel Massive Sequencing (NGS) 96 Genes. By Reference Laboratory Genetics (Spain). RYR2, SCN1B, SCN2B, SCN4B, SCN5A, SGCD, SLC25A3, SLC6A4, SNTA1, TAZ, TCAP, TGFB3, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TSFM, TTN, TTR , (...) View the complete list with 75 more genes Panel complete gene list RYR2, SCN1B, SCN2B, SCN4B, SCN5A, SGCD, SLC25A3, SLC6A4, SNTA1, TAZ, TCAP, TGFB3, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TSFM, TTN, TTR, VCL, MYOZ2, CACNA1C, CACNA1G, CACNA1H, CACNB2, JPH2, ACTC1, CALM1, CASQ2, CAV3, LDB3, TP63, MYLK2, ACTN2, HCN4, TRPM4, SCN3B, MYPN, CRYAB, CSRP3, CTNNA3, RBM20, DES, TMEM43, GPD1L, DMD, DMPK, NEXN, DNM1L, DPP6, DSC2, DSG2, DSP, DNAJC19, ECE1, EMD, EYA4, FKTN, AKAP9, GJA1, GJA5, HCN1, ANK2, ABCC9, JUP, KCNA5, KCND3, KCNE1, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNQ1, LAMA4, LAMP2, LMNA, PHOX2A, MYBPC3, MYH6, MYH7, MYL2, MYL3, NOTCH1, NPPA, NUP155, PITX2, PKP2, PLN, PHOX2B, PRKAG2, BAG3, PTPN11, RET Specificity 2 % Genes 100 %

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Sources and references

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