Agammaglobulinemia 8, Autosomal Dominant; Agm8

Clinical Features

Phenotypes and symptoms related to Agammaglobulinemia 8, Autosomal Dominant; Agm8

  • Arthritis
  • Recurrent otitis media
  • Meningitis
  • Agammaglobulinemia
  • B lymphocytopenia

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Agammaglobulinemia 8, Autosomal Dominant; Agm8 Is also known as agammaglobulinemia, autosomal dominant, due to tcf3 defect.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Agammaglobulinemia 8, Autosomal Dominant; Agm8 Recommended genes panels

Panel Name, Specifity and genes Tested/covered
RT-PCR t(1;19)(E2A/PBX1).

By CGC Genetics (Portugal).

TCF3, PBX1
Specificity
50 %
Genes
100 %
Fluorescent in situ Hybridization - Hematopathology.

By Hartford Hospital Laboratory - Molecular Genetics and Cytogenetics Hartford Hospital-Hartford-CT-USA (United States).

BCL6, BCR, RUNX1, ABI1, TCF3, TP53, DLEU1, CRLF2, RUNX1T1, CBFB, CDKN2A, CDKN2C, CKS1B, ETV6, MECOM, FGFR1, IGH, JAK2, MYC, ABL1 , (...)

View the complete list with 7 more genes
Specificity
4 %
Genes
100 %
Antibody deficiencies Panel.

By CeGaT GmbH (Germany).

BTK, TCF3, TCF4, CD40, TNFSF12, CD40LG, UNG, AICDA, BLNK, RTEL1, CD19, CD79A, CD79B, CD81, LRBA, TNFRSF13C, TNFRSF13B, LRRC8A, CR2, DKC1 , (...)

View the complete list with 8 more genes
Specificity
4 %
Genes
100 %
Onco microarray for MDS/AML.

By Pittsburgh Cytogenetics Laboratory University of Pittsburgh Medical Center (United States).

BCR, RPN1, RUNX1, SET, TCF3, TERT, TFG, TP53, TRPS1, WT1, MRTFA, RBM15, RUNX1T1, CBFB, CBL, PICALM, MLLT10, ACSL6, ARHGAP26, ASXL1 , (...)

View the complete list with 39 more genes
Specificity
2 %
Genes
100 %
Primary Immunodeficiency Panel.

By Blueprint Genetics (Finland).

RMRP, RORC, CFB, BLM, SH2D1A, SLC7A7, SMARCAL1, SMARCD2, SRP72, BTK, STAT1, STAT2, STAT3, STAT5B, STIM1, STK4, STX11, STXBP2, TAPBP, TBX1 , (...)

View the complete list with 253 more genes
Specificity
1 %
Genes
100 %
FoundationOne® Heme.

By Foundation Medicine, Inc. (United States).

BCL6, BCL7A, ROS1, RUNX1, BLM, SDHA, SDHB, SDHC, SDHD, SF3B1, SRSF2, SGK1, FOXL2, BRAF, BRCA1, BRCA2, SMARCA1, SMARCA4, SMARCB1, ARID1A , (...)

View the complete list with 374 more genes
Specificity
1 %
Genes
100 %
Caris MI TumorSeek 592-Gene NGS Panel.

By Caris Life Sciences (United States).

BCL6, BCL7A, BCL9, BCR, ROS1, RPL10, RPL22, RPL5, RPN1, RUNX1, BLM, SDC4, SDHB, SDHC, SDHD, BMPR1A, SET, SF3B1, SFPQ, SRSF2 , (...)

View the complete list with 559 more genes
Specificity
1 %
Genes
100 %
Agammaglobulinemia NGS PANEL.

By Laboratorio de Genetica Clinica SL (Spain).

BTK, TCF3, BLNK, CD79A, CD79B, LRRC8A, IGHM, IGLL1, PIK3R1
Specificity
12 %
Genes
100 %

You can get up to 3 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

OMIM Rare Disease Search Engine

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