1. Mendelian
  2. Rare Diseases
  3. AA AMYLOIDOSIS

Aa Amyloidosis

Table of contents:

Description

Secondary amyloidosis is a form of amyloidosis (see this term), that complicates chronic inflammatory disorders (mainly rheumatoid arthritis, see this term) and is characterized by the aggregation and deposition of amyloid fibrils composed of serum amyloid A protein, an acute phase reactant. Although spleen, suprarenal gland, liver and gut are frequent sites of amyloid deposition, the clinical picture is dominated by renal involvement.

Genes related to Aa Amyloidosis

  • SAA1

View recommended genes panels

Clinical Features

Top most frequent phenotypes and symptoms related to Aa Amyloidosis

  • Hepatomegaly
  • Vomiting
  • Abnormal heart morphology
  • Abdominal pain
  • Hypothyroidism
  • Proteinuria
  • Abnormality of the kidney
  • Malabsorption
  • Nausea
  • Nephropathy

And another 20 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Alternative names

Aa Amyloidosis Is also known as secondary amyloidosis, inflammatory amyloidosis, reactive amyloidosis.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Aa Amyloidosis Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Familial mediterranean fever.

By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders (Germany).

SAA1, TNFRSF1A, MEFV
Specificity
34 %
Genes
100 %
SAA1.

By Fulgent Genetics Fulgent Genetics (United States).

SAA1
Specificity
100 %
Genes
100 %

You can get up to -6 more panels with our dedicated tool

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Sources and references

You can check the following sources for additional information.

ORPHANET Rare Disease Search Engine

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