Xeroderma Pigmentosum Group G

Description

For a general description of xeroderma pigmentosum, see XPA (OMIM ), and of Cockayne syndrome, see CSA (OMIM ). Complementation group G has one of the smallest series of cases (Arlett et al., 1980).

Incidence and onset information

Not enough data available about incidence and published cases.
— Variable expressivity

Xeroderma Pigmentosum Group G Common symptoms

Top most frequent phenotypes related to Xeroderma Pigmentosum Group G

  • Defective DNA repair after ultraviolet radiation damage
  • Cutaneous photosensitivity
  • Tremor
  • Pes cavus
  • Microphthalmia
  • Growth delay
  • Spasticity
  • Cataract
  • Ataxia
  • Microcephaly
And 1 less frequent phethotypes (you can get a complete list using our application).

Genes related to Xeroderma Pigmentosum Group G

  • ERCC5

Xeroderma Pigmentosum Group G Recommended genes panels

Panel Name & Genes Tested specificity Genes covered
Ataxia Exome Panel

AAAS, AHI1, HIBCH, SPG21, AP1S2, AP4M1, AP4S1, ALG6, ARL6IP1, NAXE, ABCD1, ALS2, APOB, BTD, HSD17B4, ACO2, ATM, ATP7B, ATP8A2, CACNB4 , (...)

View the complete list with 460 more genes

More info about this panel
1 % 100 %
CHOP Comprehensive Hereditary Cancer Panel

XPA, GBA, SMARCA4, SDHAF2, SDHC, RUNX1, SMARCB1, COL7A1, SH2D1A, SMAD4, SLC25A13, SDHA, GJB2, CEBPA, POLE, PTPN11, RECQL4, RAD51D, HMBS, RMRP , (...)

View the complete list with 86 more genes

More info about this panel
1 % 100 %
OncoRisk Plus (NGS panel for 89 genes)

PMS2, SMARCB1, SUFU, KIT, GATA2, ALK, AIP, BAP1, DDB2, DIS3L2, ERCC3, FANCF, FANCD2, FANCC, FANCL, FANCI, XPC, TSC1, TSC2, TMEM127 , (...)

View the complete list with 69 more genes

More info about this panel
2 % 100 %
Xeroderma Pigmentosum Sequencing Panel

XPA, ERCC3, POLH, DDB2, XPC, ERCC4, ERCC2, ERCC5

More info about this panel
13 % 100 %
Xeroderma Pigmentosum via the ERCC5 Gene

ERCC5

More info about this panel
100 % 100 %
Cataract

CHMP4B, COL4A1, COL2A1, COL4A2, CRYBA1, GALK1, SLC33A1, FOXE3, CRYGS, RAB3GAP2, SLC16A12, SIX6, PITX2, HSF4, RAB18, EPG5, MIR184, RAB3GAP1, GLA, OPA3 , (...)

View the complete list with 45 more genes

More info about this panel
2 % 100 %
Eye Diseases - panels

ADAMTS10, TREX1, ADAMTS2, ACTG1, ALDH1A3, PHOX2A, ADAMTS17, BCOR, BMP7, VSX2, CTDP1, COL3A1, CHD7, COL9A1, ERCC6, CRYBA1, CRYBB1, CYP4V2, CHMP4B, FRMD7 , (...)

View the complete list with 146 more genes

More info about this panel
1 % 100 %
Hereditary Cancer Syndromes - panels

AIP, ALK, ATM, BRCA2, BMPR1A, BAP1, BRIP1, BRCA1, CDH1, CDK4, CDKN2A, CHEK2, DDB2, GREM1, EPCAM, ERCC3, FANCB, GATA2, MSH6, NBN , (...)

View the complete list with 80 more genes

More info about this panel
1 % 100 %
Microphthalmia-Anophthalmia-Coloboma Complex (MAC)

BCOR, CHD7, RAB3GAP2, GDF6, FREM2, GJA1, RAX, HCCS, GRIP1, ZIC2, STRA6, MFRP, ALDH1A3, VSX2, PAX2, RAB3GAP1, PRSS56, RAB18, HMX1, TFAP2A , (...)

View the complete list with 28 more genes

More info about this panel
3 % 100 %
AllNeuro panel

ADSL, JRK, CAV3, VDAC1, AMPD2, ARSI, TTN, NEDD4L, TFG, DHTKD1, MAG, MTHFR, ABHD5, ACTG1, ALG12, ALG6, ACY1, ADK, AGXT, IDUA , (...)

View the complete list with 1185 more genes

More info about this panel
1 % 100 %
Disorders associated with malignancy Panel

TSC1, PMS2, RTEL1, ATM, ERCC8, NF1, DKC1, SDHB, PTEN, MSH2, ERCC3, POLH, RECQL4, TSC2, SDHD, MSH6, ERCC6, FERMT1, STK11, XPC , (...)

View the complete list with 25 more genes

More info about this panel
3 % 100 %
Xeroderma pigmentosum Panel

XPC, ERCC3, DDB2, XPA, POLH, ERCC2, ERCC5, ERCC4

More info about this panel
13 % 100 %
Ataxia and differential diagnoses Panel

CYP27A1, GRID2, CACNA1A, COX20, EIF2B3, KIF1C, SLC19A3, ATP7B, CLN6, NEU1, CSTB, PDP1, ATCAY, SNAP25, NPC1, EIF2B1, ERCC3, TTC19, ERCC6, TDP1 , (...)

View the complete list with 184 more genes

More info about this panel
1 % 100 %
Single gene testing ERCC5

ERCC5

More info about this panel
100 % 100 %
Progeria syndromes Panel

ERCC3, ERCC8, ERCC6, LMNA, GTF2H5, PTDSS1, POLD1, RECQL4, PYCR1, WRN, B4GALT7, BLM, BANF1, ALDH18A1, ERCC5, ERCC4, ERCC2, ZMPSTE24

More info about this panel
6 % 100 %
Cancer Predisposition

HRAS, PTEN, WT1, TP53, SMARCB1, SMAD4, SDHB, PALB2, NF1, MUTYH, MEN1, KIT, CHEK2, AIP, SUFU, RET, ALK, MET, STK11, VHL , (...)

View the complete list with 69 more genes

More info about this panel
2 % 100 %
Neuromuscular Comprehensive Panel

KIF21A, COA3, NDUFB3, DYSF, PIEZO2, MYH3, ERCC6, RAPSN, NDUFAF4, APOPT1, FOXRED1, SYT2, SGCE, NDUFAF1, SCO1, NDUFA1, TRPV4, FARS2, OPA1, ITGA7 , (...)

View the complete list with 285 more genes

More info about this panel
1 % 100 %
ONCOLOGY, PANEL

BRCA1, ATM, BRCA2, BMPR1A, BRIP1, CDH1, CDKN1B, DKC1, CDK4, CDKN2A, CHEK2, ELANE, GREM1, ERCC3, FANCB, MSH6, NBN, HOXB13, SMAD4, MEN1 , (...)

View the complete list with 60 more genes

More info about this panel
2 % 100 %
ERCC5-related xeroderma pigmentosum

ERCC5

More info about this panel
100 % 100 %
Inheritest NGS, Comprehensive

IDUA, ADAMTS2, ALPL, AGXT, HSD17B4, DHCR7, ACAT1, ATM, ATP7B, ARSB, CPS1, BBS10, BCKDHA, COL4A3, CFTR, GAA, GLDC, HGSNAT, MEFV, LAMB3 , (...)

View the complete list with 120 more genes

More info about this panel
1 % 100 %
Hereditary Cancer NGS Panel

HRAS, WT1, PTPN11, PTEN, RBBP8, BRCA2, AIP, XRCC2, RB1, SDHD, SMARCB1, RET, EXT1, APC, HOXB13, MSH6, PMS2, SDHAF2, PICALM, SDHC , (...)

View the complete list with 92 more genes

More info about this panel
1 % 100 %
Intellectual Disability NGS Panel

POMT1, FKTN, FKRP, MAPT, KRAS, PTPN11, GBA, PTEN, RBBP8, ATP1A2, FGFR2, BRCA2, PCNT, HAX1, USP9X, GAMT, SLC2A1, STXBP1, FOXG1, MECP2 , (...)

View the complete list with 372 more genes

More info about this panel
1 % 100 %
Xeroderma Pigmentosum NGS Panel

XPA, ERCC3, XPC, DDB2, ERCC2, ERCC5, ERCC4

More info about this panel
15 % 100 %
Xeroderma Pigmentosum NGS Panel

XPA, ERCC3, POLH, XPC, DDB2, ERCC1, ERCC2, ERCC4, ERCC5

More info about this panel
12 % 100 %
ERCC5

ERCC5

More info about this panel
100 % 100 %
Comprehensive Cancer Panel

TMEM127, RET, RAD51, CDH1, FANCD2, DDB2, CDKN1B, MPL, XPA, KIT, POLE, PMS1, EGLN1, XPC, TSC2, RECQL4, BRIP1, GALNT12, FANCB, AIP , (...)

View the complete list with 104 more genes

More info about this panel
1 % 100 %
Progeria and Progeroid Syndromes Panel

AGPAT2, BSCL2, COL3A1, ERCC6, LMNA, WRN, ERCC8, PYCR1, RECQL4, ALDH18A1, ERCC2, ERCC4, ERCC5, B4GALT7, BLM, ZMPSTE24

More info about this panel
7 % 100 %
Microphthalmia, Anophthalmia and Anterior Segment Dysgenesis Panel

BCOR, CHD7, ERCC6, FOXE3, HCCS, COL4A1, OCRL, PAX2, PQBP1, RAB3GAP1, SIX3, GJA1, PITX2, ZIC2, STRA6, TFAP2A, ABCB6, VPS13B, FOXL2, ERCC2 , (...)

View the complete list with 12 more genes

More info about this panel
4 % 100 %
Hereditary Melanoma and Skin Cancer Panel

BAP1, BRCA2, BRCA1, CDK4, CDKN2A, DDB2, ERCC3, TP53, WRN, RB1, PTEN, SUFU, XPC, XPA, ERCC2, PTCH1, ERCC4, ERCC5, MITF

More info about this panel
6 % 100 %
Xeroderma Pigmentosum Panel

DDB2, ERCC3, XPC, XPA, ERCC2, ERCC4, ERCC5

More info about this panel
15 % 100 %
Cataract Panel

BCOR, ERCC6, CRYBB1, FOXE3, GALK1, LIM2, GALT, HSF4, COL2A1, COL4A1, OCRL, OPA3, RAB3GAP1, SLC33A1, TMEM70, GJA1, AGK, WRN, TDRD7, MAF , (...)

View the complete list with 34 more genes

More info about this panel
2 % 100 %
Comprehensive Skeletal / Malformation Syndrome Panel

ABCC6, DHCR24, ADAMTS10, ADAMTS2, ACTA1, ACTG1, ALPL, AGPS, ANKH, PAPSS2, DHCR7, ARX, ARID1A, ALX3, BMPR1A, CENPJ, OFD1, COL1A2, COL3A1, CUL4B , (...)

View the complete list with 409 more genes

More info about this panel
1 % 100 %
Comprehensive Hereditary Cancer Panel

ALK, ATM, BRCA2, BMPR1A, BAP1, BRIP1, BRCA1, CDH1, CDKN1B, DKC1, CDK4, CDKN2A, CHEK2, DDB2, ELANE, GREM1, EPCAM, ERCC3, FANCB, GATA2 , (...)

View the complete list with 96 more genes

More info about this panel
1 % 100 %
Arthrogryposes Panel

DHCR24, DPAGT1, ERCC6, CHAT, CFL2, FKTN, GBA, MYH3, NEB, MTM1, ECEL1, TGFB3, TPM2, TK2, TSEN54, MYH2, SCO2, TRPV4, CHST14, CHRNA1 , (...)

View the complete list with 38 more genes

More info about this panel
2 % 100 %
XERODERMA PIGMENTOSUM

DDB2, XPA, POLH, XPC, ERCC3, ERCC2, ERCC1, ERCC5, ERCC4

More info about this panel
12 % 100 %
152 Integrated Advantage NGS Solid Tumor Panel

MAP2K4, XPA, TOP2A, XPC, PIK3CA, NRAS, KRAS, EP300, EMSY, ABCB1, CDKN1B, MYCN, TSC1, KDR, AR, MAP2K1, AKT3, IDH2, TOP2B, SMAD4 , (...)

View the complete list with 132 more genes

More info about this panel
1 % 100 %

Alternate names

Xeroderma Pigmentosum Group G Is also known as xp, group g;xpgc, xeroderma pigmentosum vii;xp7.

Sources

OMIM

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