Xeroderma Pigmentosum Group G

Description

For a general description of xeroderma pigmentosum, see XPA (OMIM ), and of Cockayne syndrome, see CSA (OMIM ). Complementation group G has one of the smallest series of cases (Arlett et al., 1980).

Incidence and onset information

Not enough data available about incidence and published cases.
— Variable expressivity

Xeroderma Pigmentosum Group G Common symptoms

Phenotypes related to Xeroderma Pigmentosum Group G

  • Defective DNA repair after ultraviolet radiation damage
  • Cutaneous photosensitivity
  • Pes cavus
  • Tremor
  • Microphthalmia
  • Growth delay
  • Spasticity
  • Cataract
  • Ataxia
  • Microcephaly
  • Autosomal recessive inheritance

Genes related to Xeroderma Pigmentosum Group G

  • ERCC5

Xeroderma Pigmentosum Group G Recommended genes panels

Panel Name & Genes Tested specificity Genes covered
Ataxia Exome Panel

AAAS, AHI1, NT5C2, PTS, AP4M1, AP4B1, AP4E1, AP4S1, ARL6IP1, NAXE, APTX, RARS2, ABCD1, RARS, BTD, HSD17B4, ACO2, ATM, ATP7B, ATP1A3 , (...)

View the complete list with 460 more genes

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1 % 100 %
CHOP Comprehensive Hereditary Cancer Panel

XPA, GBA, SMARCA4, SDHC, RUNX1, SMAD4, RAD51C, GJB2, PTPN11, RAD51D, PTCH1, SDHB, PRKAR1A, ARID5B, CHEK2, RHBDF2, PTEN, IKZF1, PAX5, NBN , (...)

View the complete list with 86 more genes

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1 % 100 %
OncoRisk Plus (NGS panel for 89 genes)

PMS2, SLX4, BLM, DICER1, ERCC2, ERCC4, FANCG, EZH2, FANCL, TSC1, TMEM127, XPA, WRN, CEP57, CYLD, RAD51D, PRF1, PTCH1, RUNX1, BRCA1 , (...)

View the complete list with 69 more genes

More info about this panel
2 % 100 %
Xeroderma Pigmentosum Sequencing Panel

ERCC4, ERCC2, XPA, ERCC5, DDB2, POLH, XPC, ERCC3

More info about this panel
13 % 100 %
Xeroderma Pigmentosum via the ERCC5 Gene

ERCC5

More info about this panel
100 % 100 %
Mental retardation - different panels

UBR1, UPB1, GATM, MOGS, KIF11, BCS1L, ANKH, RAB3GAP1, COG5, TUBGCP6, RMND1, SPATA5, TUBA8, GBA2, ZNF711, ACOX1, ISPD, ATP6V0A2, SETD5, SURF1 , (...)

View the complete list with 847 more genes

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1 % 100 %
Cataract

CHMP4B, ABCB6, COL4A1, COL2A1, COL11A1, CRYGB, FOXC1, SLC16A12, SIX6, PITX2, PAX6, HSF4, EPG5, CRYGD, EPHA2, BFSP1, ERCC1, LTBP2, RAB3GAP1, SIL1 , (...)

View the complete list with 45 more genes

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2 % 100 %
Eye Diseases - panels

ABCB6, ADAMTS2, BCOR, BMP7, VSX2, BFSP1, COL3A1, CRYBA4, CHD7, CHMP4B, EYA1, FAM126A, FBN1, GLA, GJA8, EPHA2, GRIP1, ERCC1, ERCC2, JAM3 , (...)

View the complete list with 147 more genes

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1 % 100 %
Hereditary Cancer Syndromes - panels

ATM, BRCA2, BRIP1, BRCA1, CDH1, CDKN1C, CDKN2A, CHEK2, DICER1, GREM1, HNF1A, EGFR, EPCAM, ERCC2, FANCB, FH, MSH6, NBN, PTCH1, SMAD4 , (...)

View the complete list with 80 more genes

More info about this panel
1 % 100 %
Microphthalmia-Anophthalmia-Coloboma Complex (MAC)

SALL2, BMP4, BCOR, ABCB6, CYP1B1, CRYBA4, CHD7, ERCC2, ERCC1, GDF6, GDF3, GJA1, RAX, HCCS, GRIP1, SOX2, MAB21L2, VSX2, TGIF1, RAB3GAP1 , (...)

View the complete list with 28 more genes

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3 % 100 %
AllNeuro panel

MTOR, JRK, CAV3, NXF5, AMPD2, SCN3A, ZCCHC12, ARSI, USP8, TTN, TBL1XR1, TFG, DHTKD1, ERLIN1, LIMS2, MAG, DAG1, HMGCS2, MTR, PTS , (...)

View the complete list with 1185 more genes

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1 % 100 %
Disorders associated with malignancy Panel

TSC1, TINF2, NOP10, PMS2, RTEL1, ATM, ERCC2, ERCC8, PTCH1, NF1, WRAP53, DKC1, TERT, SDHB, PTEN, MSH2, PRKAR1A, PDGFRB, RHBDF2, MSH6 , (...)

View the complete list with 25 more genes

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3 % 100 %
Xeroderma pigmentosum Panel

ERCC2, XPA, ERCC4, XPC, ERCC3, DDB2, POLH, ERCC5

More info about this panel
13 % 100 %
Ataxia and differential diagnoses Panel

CYP27A1, POLR3A, CACNA1A, COX20, GMPPB, RARS, APTX, NHLRC1, KIF1C, CLCN2, ATP7B, NEU1, PDP1, SNAP25, NPC1, CA8, RPGRIP1L, SLC17A5, CWF19L1, TDP1 , (...)

View the complete list with 184 more genes

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1 % 100 %
Single gene testing ERCC5

ERCC5

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100 % 100 %
Progeria syndromes Panel

B4GALT7, BLM, ERCC4, ERCC2, ERCC8, LMNA, GTF2H5, PYCR1, WRN, BANF1, ALDH18A1, ERCC5, ERCC3, ERCC6, PTDSS1, POLD1, RECQL4, ZMPSTE24

More info about this panel
6 % 100 %
Cancer Predisposition

HRAS, PTEN, WT1, TP53, SMAD4, SDHB, PRKAR1A, PALB2, NF1, MUTYH, EGFR, CHEK2, DICER1, RAD51C, RET, PTCH1, MET, STK11, VHL, NBN , (...)

View the complete list with 69 more genes

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2 % 100 %
Neuromuscular Comprehensive Panel

KIF21A, COA3, NDUFB3, DYSF, NDUFS1, PIEZO2, BIN1, RAPSN, APOPT1, SYT2, SGCE, NEK9, SCO1, NDUFA1, TRPV4, ITGA7, ACTA1, PTEN, MYPN, CAV3 , (...)

View the complete list with 285 more genes

More info about this panel
1 % 100 %
ONCOLOGY, PANEL

BRCA1, ATM, BRCA2, BRIP1, CDH1, CDKN1B, DKC1, CDKN2A, CHEK2, GREM1, ERCC2, FANCB, FH, MSH6, NBN, PTCH1, SMAD4, MLH1, MSH2, PRKAR1A , (...)

View the complete list with 60 more genes

More info about this panel
2 % 100 %
ERCC5-related xeroderma pigmentosum

ERCC5

More info about this panel
100 % 100 %
Inheritest NGS, Comprehensive

ADA, ADAMTS2, ALPL, AGL, HSD17B4, ATM, ATP7B, BCS1L, BCKDHB, BBS10, BCKDHA, CLN8, CLRN1, CFTR, GAA, GLDC, HADHA, LAMB3, FKTN, GBA , (...)

View the complete list with 120 more genes

More info about this panel
1 % 100 %
Hereditary Cancer NGS Panel

HRAS, WT1, PTPN11, PTEN, RBBP8, BRCA2, PRKAR1A, ERCC4, XRCC3, MSH3, ERCC2, RET, EXO1, APC, CTNNB1, MSH6, PMS2, SDHC, MPL, TP53 , (...)

View the complete list with 92 more genes

More info about this panel
1 % 100 %
Intellectual Disability NGS Panel

SATB2, POMT1, FKTN, FKRP, POMT2, KRAS, PTPN11, GBA, PTEN, RBBP8, ATP1A2, FGFR2, BRCA2, PRKAR1A, PAX6, HAX1, USP9X, RAB40AL, GAMT, SLC2A1 , (...)

View the complete list with 372 more genes

More info about this panel
1 % 100 %
Xeroderma Pigmentosum NGS Panel

XPA, ERCC2, ERCC4, ERCC5, DDB2, ERCC3, XPC

More info about this panel
15 % 100 %
Xeroderma Pigmentosum NGS Panel

XPA, ERCC1, ERCC4, ERCC2, XPC, ERCC5, DDB2, ERCC3, POLH

More info about this panel
12 % 100 %
ERCC5

ERCC5

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100 % 100 %
Comprehensive Cancer Panel

TMEM127, RET, CDH1, CDKN1B, MPL, XPA, EXO1, MAX, EGLN1, BRIP1, FANCB, KIF1B, CYLD, RBBP8, MUTYH, ERCC4, FANCL, ROBO2, ERCC2, MSH3 , (...)

View the complete list with 104 more genes

More info about this panel
1 % 100 %
Progeria and Progeroid Syndromes Panel

AGPAT2, COL3A1, ERCC2, ERCC4, B4GALT7, LMNA, WRN, BLM, ERCC8, PYCR1, ALDH18A1, BSCL2, ERCC6, ERCC5, RECQL4, ZMPSTE24

More info about this panel
7 % 100 %
Microphthalmia, Anophthalmia and Anterior Segment Dysgenesis Panel

ABCB6, BCOR, CHD7, ERCC2, HCCS, COL4A1, CYP1B1, OCRL, PAX6, RAB3GAP1, FOXC1, GJA1, PITX2, BMP4, SOX2, VPS13B, ERCC6, FOXE3, FOXL2, NDP , (...)

View the complete list with 12 more genes

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4 % 100 %
Hereditary Melanoma and Skin Cancer Panel

BRCA2, BRCA1, CDKN2A, ERCC2, PTCH1, ERCC4, TP53, WRN, PTEN, XPA, BAP1, CDK4, DDB2, ERCC3, ERCC5, MITF, RB1, SUFU, XPC

More info about this panel
6 % 100 %
Xeroderma Pigmentosum Panel

ERCC2, ERCC4, XPA, DDB2, ERCC3, ERCC5, XPC

More info about this panel
15 % 100 %
Cataract Panel

ABCB6, BCOR, EYA1, FAM126A, GJA8, ERCC2, LIM2, HSF4, NHS, COL2A1, COL4A1, COL11A1, OCRL, PAX6, OPA3, PITX3, RAB3GAP1, SIL1, GJA1, AGK , (...)

View the complete list with 34 more genes

More info about this panel
2 % 100 %
Comprehensive Skeletal / Malformation Syndrome Panel

ABCC6, DHCR24, ADAMTS2, ACTA1, ADAMTSL2, ALPL, ARFGEF2, ANKH, RARS2, BMP2, ARX, ALX3, ATP6V0A2, BIN1, CRTAP, CENPF, CENPJ, BRWD3, CLCN5, CHRNB1 , (...)

View the complete list with 409 more genes

More info about this panel
1 % 100 %
Comprehensive Hereditary Cancer Panel

ATM, BRCA2, BRIP1, BRCA1, CDH1, CDKN1B, DKC1, CDKN1C, CDKN2A, CHEK2, DICER1, GREM1, HNF1A, EGFR, EPCAM, ERCC2, EXO1, FANCB, FH, MSH6 , (...)

View the complete list with 96 more genes

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1 % 100 %
Arthrogryposes Panel

ACTA1, DHCR24, RARS2, BIN1, CHRNB1, CHRNE, COL6A2, GLE1, CHRNG, CFL2, FKTN, GBA, NEB, PMM2, NALCN, VPS33B, AGRN, KAT6B, MYH2, SCO2 , (...)

View the complete list with 38 more genes

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2 % 100 %
XERODERMA PIGMENTOSUM

ERCC1, XPA, ERCC4, ERCC2, ERCC5, DDB2, POLH, XPC, ERCC3

More info about this panel
12 % 100 %
152 Integrated Advantage NGS Solid Tumor Panel

CTNNB1, MAP2K4, XPA, TOP2A, NRAS, PLK1, RAD51C, KRAS, GSTP1, ERCC1, CYP2D6, ABCB1, CDKN1B, MYD88, TSC1, JAK3, AR, ATRX, PDGFRB, MAP2K1 , (...)

View the complete list with 132 more genes

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1 % 100 %
Tempus xT assay

ING1, PRKAR1A, WRN, DDR2, TSC1, IFNAR2, KDM5A, HLA-A, U2AF1, BRIP1, FANCL, PTPN13, STAT5A, TRAF3, CSF1R, HNF1B, MAPK1, SMARCA4, INPP4B, NTRK1 , (...)

View the complete list with 571 more genes

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1 % 100 %
Tempus xO assay

CSK, TWIST1, NUMBL, FBXW11, MSH3, EZH1, PIM1, KLF12, CDX2, ESPL1, SETD1A, HOXC11, INTS12, EIF1AX, NAB1, NRG3, SKI, SF1, PBX3, PAK5 , (...)

View the complete list with 1693 more genes

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1 % 100 %

Alternate names

Xeroderma Pigmentosum Group G Is also known as xp, group g;xpgc, xeroderma pigmentosum vii;xp7.

Sources

OMIM ORPHANET

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XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP F; XPF