Xeroderma Pigmentosum Group C

Description

Xeroderma pigmentosum is a genetically heterogeneous condition characterized by increased sensitivity to ultraviolet (UV) irradiation and increased risk of skin cancer resulting from a defect in DNA repair. XPC is the most common form of XP in the white population, accounting for over a third of all cases in this group (review by Li et al., 1993).For a general discussion of xeroderma pigmentosum, see XPA (OMIM ).

Incidence and onset information

Not enough data available about incidence and published cases.
— Childhood onset

Xeroderma Pigmentosum Group C Common symptoms

Top most frequent phenotypes related to Xeroderma Pigmentosum Group C

  • Defective DNA repair after ultraviolet radiation damage
  • Cutaneous melanoma
  • Entropion
  • Squamous cell carcinoma of the skin
  • Poikiloderma
  • Keratitis
  • Basal cell carcinoma
  • Telangiectasia
  • Ectropion
  • Hypopigmentation of the skin
And 5 less frequent phethotypes (you can get a complete list using our application).

Genes related to Xeroderma Pigmentosum Group C

  • XPC

Xeroderma Pigmentosum Group C Recommended genes panels

Panel Name & Genes Tested specificity Genes covered
XPC. Complete sequencing

XPC

More info about this panel
100 % 100 %
Xeroderma pigmentosum disease (sequence analysis of XPC gene)

XPC

More info about this panel
100 % 100 %
OncoRisk Plus (NGS panel for 89 genes)

PMS2, SMARCB1, SUFU, KIT, GATA2, ALK, AIP, BAP1, DDB2, DIS3L2, ERCC3, FANCF, FANCD2, FANCC, FANCL, FANCI, XPC, TSC1, TSC2, TMEM127 , (...)

View the complete list with 69 more genes

More info about this panel
2 % 100 %
Xeroderma Pigmentosum via the XPC Gene

XPC

More info about this panel
100 % 100 %
Xeroderma Pigmentosum Sequencing Panel

XPA, ERCC3, POLH, DDB2, XPC, ERCC4, ERCC2, ERCC5

More info about this panel
13 % 100 %
Hereditary Cancer Syndromes - panels

AIP, ALK, ATM, BRCA2, BMPR1A, BAP1, BRIP1, BRCA1, CDH1, CDK4, CDKN2A, CHEK2, DDB2, GREM1, EPCAM, ERCC3, FANCB, GATA2, MSH6, NBN , (...)

View the complete list with 80 more genes

More info about this panel
1 % 100 %
Xeroderma pigmentosum, group C

XPC

More info about this panel
100 % 100 %
Disorders associated with malignancy Panel

TSC1, PMS2, RTEL1, ATM, ERCC8, NF1, DKC1, SDHB, PTEN, MSH2, ERCC3, POLH, RECQL4, TSC2, SDHD, MSH6, ERCC6, FERMT1, STK11, XPC , (...)

View the complete list with 25 more genes

More info about this panel
3 % 100 %
Xeroderma pigmentosum Panel

XPC, ERCC3, DDB2, XPA, POLH, ERCC2, ERCC5, ERCC4

More info about this panel
13 % 100 %
Ataxia and differential diagnoses Panel

CYP27A1, GRID2, CACNA1A, COX20, EIF2B3, KIF1C, SLC19A3, ATP7B, CLN6, NEU1, CSTB, PDP1, ATCAY, SNAP25, NPC1, EIF2B1, ERCC3, TTC19, ERCC6, TDP1 , (...)

View the complete list with 184 more genes

More info about this panel
1 % 100 %
Cancer Predisposition

HRAS, PTEN, WT1, TP53, SMARCB1, SMAD4, SDHB, PALB2, NF1, MUTYH, MEN1, KIT, CHEK2, AIP, SUFU, RET, ALK, MET, STK11, VHL , (...)

View the complete list with 69 more genes

More info about this panel
2 % 100 %
ONCOLOGY, PANEL

BRCA1, ATM, BRCA2, BMPR1A, BRIP1, CDH1, CDKN1B, DKC1, CDK4, CDKN2A, CHEK2, ELANE, GREM1, ERCC3, FANCB, MSH6, NBN, HOXB13, SMAD4, MEN1 , (...)

View the complete list with 60 more genes

More info about this panel
2 % 100 %
Inheritest NGS, Comprehensive

IDUA, ADAMTS2, ALPL, AGXT, HSD17B4, DHCR7, ACAT1, ATM, ATP7B, ARSB, CPS1, BBS10, BCKDHA, COL4A3, CFTR, GAA, GLDC, HGSNAT, MEFV, LAMB3 , (...)

View the complete list with 120 more genes

More info about this panel
1 % 100 %
XPC-related xeroderma pigmentosum

XPC

More info about this panel
100 % 100 %
Hereditary Cancer NGS Panel

HRAS, WT1, PTPN11, PTEN, RBBP8, BRCA2, AIP, XRCC2, RB1, SDHD, SMARCB1, RET, EXT1, APC, HOXB13, MSH6, PMS2, SDHAF2, PICALM, SDHC , (...)

View the complete list with 92 more genes

More info about this panel
1 % 100 %
Xeroderma Pigmentosum NGS Panel

XPA, ERCC3, XPC, DDB2, ERCC2, ERCC5, ERCC4

More info about this panel
15 % 100 %
Xeroderma Pigmentosum NGS Panel

XPA, ERCC3, POLH, XPC, DDB2, ERCC1, ERCC2, ERCC4, ERCC5

More info about this panel
12 % 100 %
XPC

XPC

More info about this panel
100 % 100 %
Comprehensive Cancer Panel

TMEM127, RET, RAD51, CDH1, FANCD2, DDB2, CDKN1B, MPL, XPA, KIT, POLE, PMS1, EGLN1, XPC, TSC2, RECQL4, BRIP1, GALNT12, FANCB, AIP , (...)

View the complete list with 104 more genes

More info about this panel
1 % 100 %
Hereditary Melanoma and Skin Cancer Panel

BAP1, BRCA2, BRCA1, CDK4, CDKN2A, DDB2, ERCC3, TP53, WRN, RB1, PTEN, SUFU, XPC, XPA, ERCC2, PTCH1, ERCC4, ERCC5, MITF

More info about this panel
6 % 100 %
Xeroderma Pigmentosum Panel

DDB2, ERCC3, XPC, XPA, ERCC2, ERCC4, ERCC5

More info about this panel
15 % 100 %
Comprehensive Hereditary Cancer Panel

ALK, ATM, BRCA2, BMPR1A, BAP1, BRIP1, BRCA1, CDH1, CDKN1B, DKC1, CDK4, CDKN2A, CHEK2, DDB2, ELANE, GREM1, EPCAM, ERCC3, FANCB, GATA2 , (...)

View the complete list with 96 more genes

More info about this panel
1 % 100 %
Xeroderma pigmentosum complementation group C

XPC

More info about this panel
100 % 100 %
CarrierMap

MYO15A, GJB2, MTHFR, ADAMTS2, ALG6, ALPL, AR, AGXT, ABCD1, IDUA, AMH, ARG1, BTD, HSD17B4, DHCR7, ACAT1, ATM, ATP7B, ARSB, AIRE , (...)

View the complete list with 278 more genes

More info about this panel
1 % 100 %
XERODERMA PIGMENTOSUM

DDB2, XPA, POLH, XPC, ERCC3, ERCC2, ERCC1, ERCC5, ERCC4

More info about this panel
12 % 100 %
Xeroderma Pigmentosum Group C , Sequencing XPC Gene

XPC

More info about this panel
100 % 100 %
152 Integrated Advantage NGS Solid Tumor Panel

MAP2K4, XPA, TOP2A, XPC, PIK3CA, NRAS, KRAS, EP300, EMSY, ABCB1, CDKN1B, MYCN, TSC1, KDR, AR, MAP2K1, AKT3, IDH2, TOP2B, SMAD4 , (...)

View the complete list with 132 more genes

More info about this panel
1 % 100 %

Alternate names

Xeroderma Pigmentosum Group C Is also known as xpcc, xp, group c, xeroderma pigmentosum iii;xp3.

Sources

OMIM

Other rare diseases that you may find interesting

XERODERMA PIGMENTOSUM GROUP D