Lymphoma, and Dental crowding

Diseases related with Lymphoma and Dental crowding

In the following list you will find some of the most common rare diseases related to Lymphoma and Dental crowding that can help you solving undiagnosed cases.


Top matches:

Medium match SECKEL SYNDROME 1; SCKL1


Seckel syndrome is a rare autosomal recessive disorder characterized by intrauterine growth retardation, dwarfism, microcephaly with mental retardation, and a characteristic 'bird-headed' facial appearance (Shanske et al., 1997). Genetic Heterogeneity of Seckel SyndromeOther forms of Seckel syndrome include SCKL2 (OMIM ), caused by mutation in the RBBP8 gene (OMIM ) on chromosome 18q11; SCKL4 (OMIM ), caused by mutation in the CENPJ gene (OMIM ) on chromosome 13q12; SCKL5 (OMIM ), caused by mutation in the CEP152 gene (OMIM ) on chromosome 15q21; SCKL6 (OMIM ), caused by mutation in the CEP63 gene (OMIM ) on chromosome 3q22; SCKL7 (OMIM ), caused by mutation in the NIN gene (OMIM ) on chromosome 14q22; SCKL8 (OMIM ), caused by mutation in the DNA2 gene (OMIM ) on chromosome 10q21; SCKL9 (OMIM ), caused by mutation in the TRAIP gene (OMIM ) on chromosome 3p21; and SCKL10 (OMIM ), caused by mutation in the NSMCE2 gene (OMIM ) on chromosome 8q24.The report of a Seckel syndrome locus on chromosome 14q, designated SCKL3, by Kilinc et al. (2003) was found to be in error; see HISTORY.

SECKEL SYNDROME 1; SCKL1 Is also known as bird-headed dwarfism|nanocephalic dwarfism|sckl|microcephalic primordial dwarfism i|seckel-type dwarfism

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Microcephaly
  • Scoliosis


SOURCES: OMIM MENDELIAN

More info about SECKEL SYNDROME 1; SCKL1

Low match RUBINSTEIN-TAYBI SYNDROME 1; RSTS1


Rubinstein-Taybi syndrome is a multiple congenital anomaly syndrome characterized by mental retardation, postnatal growth deficiency, microcephaly, broad thumbs and halluces, and dysmorphic facial features. The facial appearance is striking, with highly arched eyebrows, long eyelashes, downslanting palpebral fissures, broad nasal bridge, beaked nose with the nasal septum, highly arched palate, mild micrognathia, and characteristic grimacing or abnormal smile. Affected individuals also have an increased risk of tumor formation (Rubinstein and Taybi, 1963; review by Hennekam, 2006).Floating-Harbor syndrome (OMIM ), which shows phenotypic overlap with Rubinstein-Taybi syndrome, is caused by mutation in the SRCAP gene (OMIM ), a coactivator for CREBBP. Genetic Heterogeneity of Rubinstein-Taybi SyndromeRubinstein-Taybi syndrome-1 (RSTS1) constitutes about 50 to 70% of patients with the disorder. Rubinstein-Taybi syndrome-2 (RSTS2 ) comprises about 3% of patients and is primarily due to de novo heterozygous mutation in the EP300 gene (OMIM ) on chromosome 22q13 (Bartsch et al., 2010).See also chromosome 16p13.3 deletion syndrome (OMIM ), a severe form of Rubinstein-Taybi syndrome resulting from a contiguous gene deletion involving the CREBBP gene as well as other neighboring genes.

RUBINSTEIN-TAYBI SYNDROME 1; RSTS1 Is also known as broad thumbs and great toes, characteristic facies, and mental retardation|rubinstein syndrome|rsts|broad thumb-hallux syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Generalized hypotonia
  • Hearing impairment


SOURCES: OMIM MENDELIAN

More info about RUBINSTEIN-TAYBI SYNDROME 1; RSTS1

Low match PITT-HOPKINS SYNDROME


Pitt-Hopkins syndrome (PHS) is characterized by the association of intellectual deficit, characteristic facial dysmorphism and problems of abnormal and irregular breathing.

PITT-HOPKINS SYNDROME Is also known as encephalopathy, severe epileptic, with autonomic dysfunction|mental retardation, syndromal, with intermittent hyperventilation

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Hearing impairment


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about PITT-HOPKINS SYNDROME

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Other less relevant matches:

Low match MENTAL RETARDATION, X-LINKED 41; MRX41


Nonsyndromic mental retardation.

MENTAL RETARDATION, X-LINKED 41; MRX41 Is also known as mental retardation, x-linked 48|mrx48

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Cognitive impairment


SOURCES: OMIM MENDELIAN

More info about MENTAL RETARDATION, X-LINKED 41; MRX41

Low match HEIMLER SYNDROME 2; HMLR2


Heimler syndrome, which represents the mildest end of the peroxisomal biogenesis disorder spectrum (see PBD1A, {214100}), is a rare autosomal recessive disorder characterized by sensorineural hearing loss, enamel hypoplasia of the secondary dentition, and nail abnormalities (Ratbi et al., 2015).For a discussion of genetic heterogeneity of Heimler syndrome, see HMLR1 (OMIM ).

HEIMLER SYNDROME 2; HMLR2 Is also known as peroxisome biogenesis disorder 4c|pbd4c

Related symptoms:

  • Hearing impairment
  • Sensorineural hearing impairment
  • Talipes equinovarus
  • Pes planus
  • Bilateral sensorineural hearing impairment


SOURCES: OMIM MENDELIAN

More info about HEIMLER SYNDROME 2; HMLR2

Low match MENTAL RETARDATION, X-LINKED 19; MRX19


X-linked mental retardation-19 (MRX19) is a nonsyndromic form of mild to moderate mental retardation. Carrier females may be mildly affected. Mutation in the RPS6KA3 gene also causes Coffin-Lowry syndrome (CLS ), a mental retardation syndrome with dysmorphic facial features and skeletal anomalies. Some patients with RPS6KA3 mutations have an intermediate phenotype with mental retardation and only mild anomalies reminiscent of CLS. These individuals have mutations resulting in some residual protein function, which likely explains the milder phenotype (summary by Field et al., 2006).

Related symptoms:

  • Intellectual disability
  • Short stature
  • Generalized hypotonia
  • Scoliosis
  • Hypertelorism


SOURCES: OMIM MESH MENDELIAN

More info about MENTAL RETARDATION, X-LINKED 19; MRX19

Low match MENTAL RETARDATION, ANTERIOR MAXILLARY PROTRUSION, AND STRABISMUS; MRAMS


Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Hearing impairment
  • Strabismus


SOURCES: OMIM MENDELIAN

More info about MENTAL RETARDATION, ANTERIOR MAXILLARY PROTRUSION, AND STRABISMUS; MRAMS

Low match AURICULOCONDYLAR SYNDROME


Auriculo-condylar syndrome (ACS) presents with bilateral external ear malformations ('question mark' ears), mandibular condyle hypoplasia, microstomia, micrognathia, microglossia and facial asymmetry. Additional manifestations include hypotonia, ptosis, cleft palate, puffy cheeks, developmental delay, impaired hearing and respiratory distress.

AURICULOCONDYLAR SYNDROME Is also known as question mark ear syndrome|question mark ears syndrome

Related symptoms:

  • Global developmental delay
  • Generalized hypotonia
  • Hearing impairment
  • Micrognathia
  • Sensorineural hearing impairment


SOURCES: ORPHANET OMIM MENDELIAN

More info about AURICULOCONDYLAR SYNDROME

Low match MENTAL RETARDATION, AUTOSOMAL DOMINANT 58; MRD58


Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Microcephaly


SOURCES: OMIM MENDELIAN

More info about MENTAL RETARDATION, AUTOSOMAL DOMINANT 58; MRD58

Low match EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE, 2; EDSMC2


The musculocontractural type of Ehlers-Danlos syndrome is characterized by progressive multisystem fragility-related manifestations, including joint dislocations and deformities; skin hyperextensibility, bruisability, and fragility, with recurrent large subcutaneous hematomas; cardiac valvular, respiratory, gastrointestinal, and ophthalmologic complications; and myopathy, featuring muscle hypoplasia, muscle weakness, and an abnormal muscle fiber pattern in histology in adulthood, resulting in gross motor developmental delay (summary by Muller et al., 2013).For a discussion of genetic heterogeneity of the musculocontractural type of Ehlers-Danlos syndrome, see EDSMC1 (OMIM ).

Related symptoms:

  • Global developmental delay
  • Hypertelorism
  • Muscle weakness
  • Abnormal facial shape
  • Pain


SOURCES: OMIM MENDELIAN

More info about EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE, 2; EDSMC2

Top 5 symptoms//phenotypes associated to Lymphoma and Dental crowding

Symptoms // Phenotype % cases
Intellectual disability Common - Between 50% and 80% cases
Global developmental delay Common - Between 50% and 80% cases
Seizures Common - Between 50% and 80% cases
Generalized hypotonia Common - Between 50% and 80% cases
Hearing impairment Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Lymphoma and Dental crowding. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Intellectual disability, moderate Downslanted palpebral fissures Hypertelorism Motor delay Abnormal facial shape Delayed speech and language development Abnormality of the pinna Pes planus High palate Microcephaly Scoliosis Strabismus Cryptorchidism Thick eyebrow Talipes equinovarus Low-set ears Abnormality of the skeletal system Wide nasal bridge Single transverse palmar crease Postnatal growth retardation Intellectual disability, severe Prominent nose Dental malocclusion Facial asymmetry Convex nasal ridge Micrognathia Narrow mouth Growth delay Hypoplasia of dental enamel Protruding ear Short stature

Rare Symptoms - Less than 30% cases


Aganglionic megacolon Failure to thrive Full cheeks Poor speech Incoordination Muscular hypotonia Coarse facial features Joint hypermobility Obstructive sleep apnea Deeply set eye Gastroesophageal reflux Short attention span Autism Constipation Ptosis Cupped ear Abnormality of the dentition Respiratory distress Patent foramen ovale Mitral regurgitation Frontal bossing Dislocated radial head Thick lower lip vermilion Thick vermilion border Posteriorly rotated ears Talipes Pulmonic stenosis Leukemia Small for gestational age Wide mouth Retrognathia Hyperactivity Pes cavus Neurological speech impairment Clinodactyly of the 5th finger Delayed skeletal maturation Clinodactyly Hypospadias Hypoplasia of the corpus callosum Ventricular septal defect Apnea Cleft palate Tapered finger Upslanted palpebral fissure Sensorineural hearing impairment Feeding difficulties Narrow palate Pes valgus Specific learning disability Wide intermamillary distance Misalignment of teeth Echolalia Astigmatism Clubbing of fingers Abnormality of the helix Breathing dysregulation Thickened helices Abnormal pattern of respiration Abdominal distention Happy demeanor Cyanosis Hypopigmentation of the skin Large beaked nose Square face Small cerebral cortex Failure of eruption of permanent teeth Narrow foot Aggressive behavior Sleep disturbance Intermittent hyperventilation Broad fingertip Triangular nasal tip Overhanging nasal tip Esophagitis Aplasia/Hypoplasia of the corpus callosum Narrow forehead Truncal ataxia Widely spaced teeth Sleep apnea Abnormal palate morphology Intellectual disability, progressive Mutism Prominent nasal bridge Hypopigmented skin patches Finger clinodactyly Coarse hair Abnormal autonomic nervous system physiology Short metatarsal Short philtrum Self-injurious behavior Severe global developmental delay Postnatal microcephaly Clubbing Open mouth Small hand Overlapping toe Supernumerary nipple Aphasia Dysphasia Hodgkin lymphoma Hyperventilation Cognitive impairment Hiatus hernia Autistic behavior Acrocyanosis External ear malformation Pointed chin Delayed ability to walk Midface retrusion Cerebral atrophy Long philtrum Myopathy Pain Muscle weakness Plagiocephaly Inguinal hernia Macrotia Postauricular skin tag Abnormality of the crus of the helix Cleft helix Cleft at the superior portion of the pinna Vein of Galen aneurysmal malformation Aplasia/Hypoplasia of the external ear Hernia Brachycephaly Mandibular condyle aplasia Blue sclerae Facial hypotonia Fragile skin Bilateral talipes equinovarus Hyperextensible skin Adducted thumb Delayed gross motor development Joint dislocation Mitral valve prolapse Arthralgia Generalized muscle weakness Bruising susceptibility Arachnodactyly Scarring Camptodactyly Telecanthus Myalgia Periauricular skin pits Hypoplasia of first ribs Absence seizures Hypermetropia Low-set, posteriorly rotated ears Macrocephaly Hyperplasia of the maxilla Open bite Amblyopia Psychosis Esotropia Long foot Round face Broad nasal tip Kyphoscoliosis Prominent forehead Intellectual disability, mild Leukonychia Taurodontia Bilateral sensorineural hearing impairment Bifid uvula Preauricular skin tag Abnormality of the temporomandibular joint Snoring Mandibular condyle hypoplasia Question mark ear Hypoplastic superior helix Anterior open-bite malocclusion Overfolding of the superior helices Speech articulation difficulties Difficulty in tongue movements Hamartoma of tongue Abnormality of the outer ear Impaired mastication Stenosis of the external auditory canal Microglossia Ankylosis Glossoptosis Facial cleft Atresia of the external auditory canal Anxiety Keloids Mandibular prognathia Behavioral abnormality Abnormal heart morphology Arrhythmia Patent ductus arteriosus Pectus excavatum Immunodeficiency Syndactyly Atrial septal defect Glaucoma Dysphagia Hyperreflexia Epicanthus Hypertension Flexion contracture Cataract Agenesis of corpus callosum Polydactyly Hypoplasia of proximal fibula Unsteady gait Otitis media Hypoplasia of the maxilla Recurrent fractures Highly arched eyebrow Iris coloboma Hirsutism Coloboma Proptosis Respiratory tract infection Feeding difficulties in infancy Abnormality of the kidney Joint laxity EEG abnormality Thin upper lip vermilion Polyhydramnios Neoplasm Large basal ganglia Low posterior hairline Synophrys Narrow face Pachygyria Cerebellar vermis hypoplasia Pancytopenia Sloping forehead Triangular face Hip dislocation Sandal gap Microtia Blepharophimosis Hyperlordosis Severe short stature Kyphosis Intrauterine growth retardation Anemia Elbow flexion contracture Myelodysplasia Hypoplasia of proximal radius 11 pairs of ribs Abnormal finger flexion creases Ivory epiphyses Small anterior fontanelle Lumbar scoliosis Selective tooth agenesis Acute monocytic leukemia Abnormal cortical gyration Clitoral hypertrophy Abnormally large globe Chromosome breakage Cone-shaped epiphyses of the phalanges of the hand Severe intrauterine growth retardation Proportionate short stature Acute myeloid leukemia Myeloid leukemia Coarctation of aorta Broad thumb Gait ataxia Dyscalculia Narrow maxilla Large foramen magnum Agoraphobia Bifid uterus Vascular ring Duplication of phalanx of hallux Chorioretinal dystrophy Deviated nasal septum Duane anomaly Prominent fingertip pads Frontal upsweep of hair Bimanual synkinesia Short upper lip Parietal foramina Abnormality of the cervical spine Premature thelarche Talon cusp Tethered cord Fatigue Micropenis Pneumonia Encephalopathy Absent speech Short neck Anteverted nares Myopia Enlarged tonsils Depressed nasal bridge Ataxia Plantar crease between first and second toes Radial deviation of thumb terminal phalanx Abnormal number of teeth High axial triradius Papillary cystadenoma of the epididymis Facial grimacing Phonophobia Long eyelashes Laryngomalacia Neurofibromas Congenital glaucoma Truncal obesity Delayed cranial suture closure Broad hallux Impulsivity Recurrent upper respiratory tract infections Shawl scrotum Bicuspid aortic valve Spina bifida occulta Low anterior hairline Wide anterior fontanel Cafe-au-lait spot Exotropia Stereotypy Neuroblastoma Overweight Broad distal phalanx of finger Abnormality of refraction Rhabdomyosarcoma Nasolacrimal duct obstruction Abnormal cornea morphology Medulloblastoma Pheochromocytoma Avascular necrosis of the capital femoral epiphysis Flared iliac wings Poor coordination Dyslexia Meningioma Hypoplastic iliac wing Low hanging columella Capillary hemangioma Self-mutilation Patellar dislocation Hypoplasia of the musculature



If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like Myopia and Encephalocele, related diseases and genetic alterations Dysarthria and Dyskinesia, related diseases and genetic alterations Myopathy and Fatigue, related diseases and genetic alterations High palate and Encephalocele, related diseases and genetic alterations Pain and Psychosis, related diseases and genetic alterations Flexion contracture and Rhizomelia, related diseases and genetic alterations Strabismus and Tall stature, related diseases and genetic alterations

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