Pituitary Gigantism

Description

WHAT: Acromegaly: Hypersecretion of growth hormone from a pituitary tumor resulting in insidious increase in the skeleton, soft tissues and organs. WHY: Acromegaly can result in an arthropathy with initial cartilage hypertrophy resulting in widening of the cartilage space on radiographs. The cartilage then undergoes premature osteoarthritis change with productive bony change characterized by broad distal tufts in the phalanges.

Clinical Features

Top most frequent phenotypes and symptoms related to Pituitary Gigantism

  • Frontal bossing
  • Hyperhidrosis
  • Mandibular prognathia
  • Coarse facial features
  • Hypertrophic cardiomyopathy
  • Amenorrhea
  • Type II diabetes mellitus
  • Left ventricular hypertrophy
  • Tall stature
  • Accelerated skeletal maturation

And another 10 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
No data available about the known clinical features onset.

Alternative names

Pituitary Gigantism Is also known as infantile and juvenile forms of acromegaly, hypophyseal gigantism.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Sources and references

You can check the following sources for additional information.

ORPHANET Rare Disease Symptoms Checker

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