1. Mendelian
  2. Rare Diseases
  3. PARKINSON-DEMENTIA SYNDROME

Parkinson-dementia Syndrome

Table of contents:

Genes related to Parkinson-dementia Syndrome

  • MAPT

View recommended genes panels

Clinical Features

Top most frequent phenotypes and symptoms related to Parkinson-dementia Syndrome

  • Hyperreflexia
  • Dysarthria
  • Tremor
  • Dementia
  • Kyphoscoliosis
  • Rigidity
  • Mental deterioration
  • Abnormal pyramidal sign
  • Abnormality of eye movement
  • Falls

And another 10 symptoms. If you need more information about this disease we can help you.

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Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Parkinson-dementia Syndrome Recommended genes panels

Panel Name, Specifity and genes Tested/covered
MAPT DNA Sequencing Test.

By Athena Diagnostics Inc (United States).

MAPT
Specificity
100 %
Genes
100 %
Frontotemporal Dementia (FTD) Evaluation.

By Athena Diagnostics Inc (United States).

C9orf72, GRN, MAPT
Specificity
34 %
Genes
100 %
Frontotemporal Dementia (FTDP) - MAPT Gene, Exon 10 Only.

By Center for Genetics at Saint Francis Saint Francis Hospital (United States).

MAPT
Specificity
100 %
Genes
100 %
Frontotemporal Dementia w/ Parkinsonism (FTDP) - MAPT Gene.

By Center for Genetics at Saint Francis Saint Francis Hospital (United States).

MAPT
Specificity
100 %
Genes
100 %
Dementia.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

SORL1, TARDBP, VCP, FIG4, OPTN, TREM2, CSF1R, CHMP2B, DCTN1, C9orf72, FUS, ALS2, SETX, GRN, ANG, APOE, APP, MAPT, PRNP, PSEN1 , (...)

View the complete list with 1 more genes
Specificity
5 %
Genes
100 %
Movement Disorders Panel.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

SCP2, SGCE, SLC20A2, SLC2A1, SLC6A3, SNCA, SPR, SQSTM1, SUCLA2, SUOX, TAF1, TH, TIMM8A, TREX1, MCOLN1, VPS35, FBXO7, CACNA1A, NPC2, PINK1 , (...)

View the complete list with 72 more genes
Specificity
2 %
Genes
100 %
Parkinson's Disease.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).

SLC6A3, SNCA, TAF1, TH, VPS35, FBXO7, PINK1, PARK7, LRRK2, CSF1R, DCTN1, ATP13A2, GBA, GCH1, MAPT, ATP1A3, PRKN, PLA2G6, POLG
Specificity
6 %
Genes
100 %
MAPT. Complete sequencing.

By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain).

MAPT
Specificity
100 %
Genes
100 %

You can get up to 68 more panels with our dedicated tool

Learn more

Sources and references

You can check the following sources for additional information.

OMIM ORPHANET MESH Rare Disease Symptoms Checker

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