Lipoprotein Glomerulopathy

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

Lipoprotein glomerulopathy is an uncommon kidney disease characterized by proteinuria, progressive kidney failure, and distinctive lipoprotein thrombi in glomerular capillaries (Saito et al., 2006). It mainly affects people of Japanese and Chinese origin; in these populations, it is associated with mutations in the gene that encodes apolipoprotein E (APOE ). The disorder had rarely been described in Caucasians.

Genes related to Lipoprotein Glomerulopathy

APOE

View recommended genes panels

Clinical Features

Phenotypes and symptoms related to Lipoprotein Glomerulopathy

Edema
Renal insufficiency
Carcinoma
Proteinuria
Abnormality of the kidney
Nephropathy
Glomerulopathy
Renal cell carcinoma
Hyperlipoproteinemia
Mesangial hypercellularity

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Lipoprotein Glomerulopathy Recommended genes panels

Panel Name, Specifity and genes Tested/covered
ADmark® ApoE Genotype Analysis and Interpretation (Symptomatic). By Athena Diagnostics Inc (United States). APOE Specificity 100 % Genes 100 %
Dementia. By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States). SORL1, TARDBP, VCP, FIG4, OPTN, TREM2, CSF1R, CHMP2B, DCTN1, C9orf72, FUS, ALS2, SETX, GRN, ANG, APOE, APP, MAPT, PRNP, PSEN1 , (...) View the complete list with 1 more genes Panel complete gene list SORL1, TARDBP, VCP, FIG4, OPTN, TREM2, CSF1R, CHMP2B, DCTN1, C9orf72, FUS, ALS2, SETX, GRN, ANG, APOE, APP, MAPT, PRNP, PSEN1, PSEN2 Specificity 5 % Genes 100 %
Apolipoprotein E (APOE) Genotype. By Molecular Diagnostics Laboratory University of Toledo Medical Center (United States). APOE Specificity 100 % Genes 100 %
APOE. By Institute for Human Genetics University Clinic Freiburg (Germany). APOE Specificity 100 % Genes 100 %
Alzheimer Disease Risk Factor (APOE). By GENE Núcleo de Genética Médica de Minas Gerais (Brazil). APOE Specificity 100 % Genes 100 %
Cardiovascular Disease Risk Factor (Apolipoprotein E). By Sheffield Diagnostic Genetics Service Sheffield Children's NHS Foundation Trust (United Kingdom). APOE Specificity 100 % Genes 100 %
Dyslipidemia NGS panel (29 genes), Sequence & CNV analysis. By Laboratory of genome diagnostics Academic Medical Center, University of Amsterdam (Netherlands). SAR1B, SLCO1B1, ABCG5, ABCG8, LMF1, SCARB1, APOA5, LDLRAP1, CETP, PCSK9, MYLIP, STAP1, GPIHBP1, CYP27A1, CYP7A1, ANGPTL3, APOC2, APOC3, APOE, LCAT , (...) View the complete list with 5 more genes Panel complete gene list SAR1B, SLCO1B1, ABCG5, ABCG8, LMF1, SCARB1, APOA5, LDLRAP1, CETP, PCSK9, MYLIP, STAP1, GPIHBP1, CYP27A1, CYP7A1, ANGPTL3, APOC2, APOC3, APOE, LCAT, LDLR, LIPA, LIPC, LIPG, MTTP Specificity 4 % Genes 100 %
APOE. Genotyping of the alleles E2, E3 and E4. By Instituto de Medicina Genomica Instituto de Medicina Genomica (Spain). APOE Specificity 100 % Genes 100 %

You can get up to 61 more panels with our dedicated tool

Learn more

Sources and references

You can check the following sources for additional information.

ORPHANET OMIM MESH Rare Disease Symptoms Checker

If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like ELLIPTOCYTOSIS 1; EL1 HYPERTRYPTOPHANEMIA; HYPTRP CHARCOT-MARIE-TOOTH DISEASE, RECESSIVE INTERMEDIATE B; CMTRIB MULTIPLE CONGENITAL ANOMALIES-HYPOTONIA-SEIZURES SYNDROME 3; MCAHS3 MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 1; MC5DN1 FANCONI ANEMIA, COMPLEMENTATION GROUP I; FANCI PEROXISOME BIOGENESIS DISORDER 13A (ZELLWEGER); PBD13A