KRT6C gene related symptoms and diseases
All the information presented here about the KRT6C gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to KRT6C gene
Symptoms // Phenotype | % Cases |
---|---|
Hyperkeratosis | Very Common - Between 80% and 100% cases |
Palmoplantar keratoderma | Very Common - Between 80% and 100% cases |
Oral leukoplakia | Very Common - Between 80% and 100% cases |
Pain | Uncommon - Between 30% and 50% cases |
Hyperhidrosis | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with KRT6C gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Epidermal acanthosis
- Thickened skin
- Skin vesicle
Rare diseases associated to KRT6C gene
Here you will find a list of rare diseases related to the KRT6C. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
PALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC, FOCAL 1; FNEPPK1
Alternate names
PALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC, FOCAL 1; FNEPPK1 Is also known as focal nonepidermolytic palmoplantar keratoderma, ppkfne, keratoderma, focal nonepidermolytic palmoplantar
Most common symptoms of PALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC, FOCAL 1; FNEPPK1
- Hyperkeratosis
- Palmoplantar keratoderma
- Oral leukoplakia
More info about PALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC, FOCAL 1; FNEPPK1
SOURCES: OMIM
AUTOSOMAL DOMINANT FOCAL NON-EPIDERMOLYTIC PALMOPLANTAR KERATODERMA WITH PLANTAR BLISTERING
Description
A rare, genetic, isolated, focal palmoplantar keratoderma disease characterized by focal thickening of the skin of the soles, and often of the palms, associated with minimal or no nail involvement. Patients frequently present non-epidermolytic painful plantar blistering and, occasionally, subtle oral leukokeratosis or plantar hyperhidrosis.
Most common symptoms of AUTOSOMAL DOMINANT FOCAL NON-EPIDERMOLYTIC PALMOPLANTAR KERATODERMA WITH PLANTAR BLISTERING
- Pain
- Hyperhidrosis
- Hyperkeratosis
- Palmoplantar keratoderma
- Epidermal acanthosis
More info about AUTOSOMAL DOMINANT FOCAL NON-EPIDERMOLYTIC PALMOPLANTAR KERATODERMA WITH PLANTAR BLISTERING
Search interest in KRT6C
Potential gene panels for KRT6C gene
KRT6C Panel
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the KRT6C gene.
More info about this panelIchthyoses and related disorders of cornification Panel Panel
By CeGaT GmbH Ichthyoses and related disorders of cornification Panel that also includes the following genes: SLC27A4 SNAP29 ST14 STS TAT TGM1 TGM5 VPS33B ATP2C1 NSDHL
More info about this panelSingle gene testing KRT6C Panel
By CeGaT GmbH
This panel specifically test the KRT6C gene.
More info about this panelKRT6C Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the KRT6C gene.
More info about this panelPachyonychia Congenita Panel Panel
By Blueprint Genetics Pachyonychia Congenita Panel that also includes the following genes: TRPV3 KRT6C AAGAB KRT16 KRT17 KRT6A KRT6B
More info about this panelPalmoplantar Keratoderma Panel Panel
By Blueprint Genetics Palmoplantar Keratoderma Panel that also includes the following genes: WNT10A SERPINB7 MBTPS2 TRPV3 SLURP1 KRT6C CTSC AAGAB DSG1 DSP
More info about this panelPACHYONYCHIA CONGENITA Panel
By Laboratorio de Genetica Clinica SL PACHYONYCHIA CONGENITA that also includes the following genes: KRT6C KRT16 KRT17 KRT6A KRT6B
More info about this panelPALMOPLANTAR KERATODERMA, NON-EPIDERMOLYTIC Panel
By Laboratorio de Genetica Clinica SL PALMOPLANTAR KERATODERMA, NON-EPIDERMOLYTIC that also includes the following genes: KRT6C KRT16
More info about this panelPACHYONYCHIA CONGENITA SANGER PANEL Panel
By Laboratorio de Genetica Clinica SL PACHYONYCHIA CONGENITA SANGER PANEL that also includes the following genes: KRT6C KRT16 KRT17 KRT6A KRT6B
More info about this panelPachyonychia Congenita: gene sequencing panel Panel
By CEN4GEN Institute for Genomics and Molecular Diagnostics Pachyonychia Congenita: gene sequencing panel that also includes the following genes: KRT6C KRT16 KRT17 KRT6A KRT6B
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