ZNF141 gene related symptoms and diseases
All the information presented here about the ZNF141 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to ZNF141 gene
Symptoms // Phenotype | % Cases |
---|---|
Postaxial hand polydactyly | Very Common - Between 80% and 100% cases |
Syndactyly | Uncommon - Between 30% and 50% cases |
Polydactyly | Uncommon - Between 30% and 50% cases |
Abnormality of the foot | Uncommon - Between 30% and 50% cases |
Postaxial polydactyly | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with ZNF141 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Broad thumb
- Preaxial polydactyly
- Triphalangeal thumb
- Abnormal facial shape
- Hyperhidrosis
- Broad phalanges of the 5th finger
Rare diseases associated to ZNF141 gene
Here you will find a list of rare diseases related to the ZNF141. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
POSTAXIAL POLYDACTYLY TYPE A
Alternate names
POSTAXIAL POLYDACTYLY TYPE A Is also known as postaxial polydactyly, type a, papa, polydactyly, postaxial
Description
Polydactyly refers to the occurrence of supernumerary digits and is the most frequent of congenital hand and foot deformities. Based on the location of the extra digits, polydactyly can be classified into preaxial, involving the thumb or great toe; postaxial, affecting the fifth digit; and central, involving the 3 central digits. Postaxial polydactyly (PAP) is further subclassified into 2 types: in type A, a well-formed extra digit articulates with the fifth or a sixth metacarpal, whereas in type B, a rudimentary, poorly developed extra digit is present (summary by Umm-e-Kalsoom et al., 2012).
Most common symptoms of POSTAXIAL POLYDACTYLY TYPE A
- Syndactyly
- Polydactyly
- Abnormality of the foot
- Postaxial polydactyly
- Postaxial hand polydactyly
More info about POSTAXIAL POLYDACTYLY TYPE A
POLYDACTYLY, POSTAXIAL, TYPE A6; PAPA6
Most common symptoms of POLYDACTYLY, POSTAXIAL, TYPE A6; PAPA6
- Abnormal facial shape
- Hyperhidrosis
- Postaxial hand polydactyly
- Broad phalanges of the 5th finger
More info about POLYDACTYLY, POSTAXIAL, TYPE A6; PAPA6
SOURCES: OMIM
Search interest in ZNF141
Potential gene panels for ZNF141 gene
ZNF141 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the ZNF141 gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like ADAMTS17 VAMP1 FBLN5 MMACHC EBP CTPS1 ADAM10