TNFRSF13B gene related symptoms and diseases

All the information presented here about the TNFRSF13B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to TNFRSF13B gene

Symptoms // Phenotype % Cases
IgA deficiency Very Common - Between 80% and 100% cases
Immunodeficiency Very Common - Between 80% and 100% cases
Autoimmunity Very Common - Between 80% and 100% cases
Hepatomegaly Common - Between 50% and 80% cases
IgG deficiency Common - Between 50% and 80% cases

Other less frequent symptoms and clinical features

Patients with TNFRSF13B gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Recurrent bronchitis
  • IgM deficiency
  • Diarrhea
  • Conjunctivitis
  • Recurrent bacterial infections
  • Recurrent pneumonia
  • Impaired T cell function
  • Recurrent infection of the gastrointestinal tract

And 43 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to TNFRSF13B gene

Here you will find a list of rare diseases related to the TNFRSF13B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


COMMON VARIABLE IMMUNODEFICIENCY


Alternate names

COMMON VARIABLE IMMUNODEFICIENCY Is also known as primary antibody deficiency, cvid, antibody deficiency due to icos defect, idiopathic immunoglobulin deficiency, primary hypogammaglobulinemia

Description

Common variable immunodeficiency (CVID) comprises a heterogeneous group of diseases characterized by a significant hypogammaglobulinemia of unknown cause, failure to produce specific antibodies after immunizations and susceptibility to bacterial infections, predominantly caused by encapsulated bacteria.

Most common symptoms of COMMON VARIABLE IMMUNODEFICIENCY

  • Hepatomegaly
  • Diarrhea
  • Splenomegaly
  • Immunodeficiency
  • Recurrent infections


More info about COMMON VARIABLE IMMUNODEFICIENCY

SOURCES: ORPHANET OMIM

IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2


Alternate names

IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2 Is also known as immunoglobulin a, selective deficiency of, taci-related, iga, selective deficiency of, taci-related

Most common symptoms of IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2

  • Immunodeficiency
  • Autoimmunity
  • IgA deficiency
  • Recurrent sinopulmonary infections
  • Recurrent infection of the gastrointestinal tract


More info about IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2

SOURCES: MESH OMIM

IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2


Alternate names

IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2 Is also known as antibody deficiency due to taci defect, hypogammaglobulinemia due to taci deficiency

Most common symptoms of IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2

  • Neoplasm
  • Hepatomegaly
  • Diarrhea
  • Splenomegaly
  • Immunodeficiency


More info about IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2

SOURCES: OMIM


Potential gene panels for TNFRSF13B gene

Common Variable Immunodeficiency Syndrome (CVID): TNFRSF13B (TACI) (Full Gene Sequencing) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta

This panel specifically test the TNFRSF13B gene.

More info about this panel

Common Variable Immunodeficiency Syndrome (CVID): TNFRSF13B (TACI) (Known Mutation) Panel

Canada.

By Molecular Diagnostic Laboratory University of Alberta

This panel specifically test the TNFRSF13B gene.

More info about this panel

TNFRSF13B Sequencing Panel

United States.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center

This panel specifically test the TNFRSF13B gene.

More info about this panel

TNFRSF13B Deletion/duplication analysis Panel

United States.

By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center

This panel specifically test the TNFRSF13B gene.

More info about this panel

Tier 2: Hereditary Lymphoma and Immunodeficiency Panel Panel

United States.

By Genetic Services Laboratory University of Chicago Tier 2: Hereditary Lymphoma and Immunodeficiency Panel that also includes the following genes: BLM SH2D1A BRCA1 BRCA2 STXBP2 FAS CD27 FASLG WAS IKZF1

More info about this panel

Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication Panel

United States.

By ARUP Laboratories, Molecular Genetics and Genomics Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication that also includes the following genes: SH2D1A BTK CD40 CD40LG UNG VAV1 AICDA BLNK CD19 CD79A

More info about this panel

TACI-Associated Common Variable Immunodeficiency (TNFRSF13B) Sequencing Panel

United States.

By ARUP Laboratories, Molecular Genetics and Genomics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Immunoglobulin A deficiency (sequence analysis of TNFRSF13B gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Immunodeficiency, common variable, 2 (sequence analysis of TNFRSF13B/TACI gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Immunodeficiency, common variable, 2 (sequence analysis of TNFRSF13B/TACI gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Common Variable Immune Deficiency/IgA Deficiency via TNFRSF13B Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Hereditary kidney disorders - different panels Panel

Germany.

By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8

More info about this panel

B cell pathology panel Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht B cell pathology panel that also includes the following genes: BTK CD40 CD40LG UNG AICDA BLNK CD19 CD79A CD79B CD81

More info about this panel

Immunodeficiency common variable type 2 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the TNFRSF13B gene.

More info about this panel

CentoICU platinum plus Panel

Germany.

By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC

More info about this panel

New Born testing (CentoICU) Panel

Germany.

By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC

More info about this panel

Antibody deficiencies Panel Panel

Germany.

By CeGaT GmbH Antibody deficiencies Panel that also includes the following genes: BTK TCF3 TCF4 CD40 TNFSF12 CD40LG UNG AICDA BLNK RTEL1

More info about this panel

Common variable Immunodefiency Panel

Denmark.

By Department of Clinical Immunology Odense University Hospital

This panel specifically test the TNFRSF13B gene.

More info about this panel

Invitae Common Variable Immunodeficiency Panel Panel

United States.

By Invitae Invitae Common Variable Immunodeficiency Panel that also includes the following genes: STAT3 CD27 TNFSF12 LRBA TNFRSF13C TNFRSF13B CR2 CTLA4 ICOS IL21

More info about this panel

Invitae Monogenic Autoimmunity Panel Panel

United States.

By Invitae Invitae Monogenic Autoimmunity Panel that also includes the following genes: RMRP SH2D1A SLC7A7 BTK STAT1 STAT3 STAT5B STIM1 STX11 STXBP2

More info about this panel

Invitae Primary Immunodeficiency Panel Panel

United States.

By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2

More info about this panel

Common Variable Immunodeficiency: TNFRSF13B gene sequence analysis Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases

This panel specifically test the TNFRSF13B gene.

More info about this panel

Common variable immunodeficiency Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Common variable immunodeficiency that also includes the following genes: CD19 CD81 TNFRSF13C TNFRSF13B CR2 ICOS IL21 MS4A1 NFKB1

More info about this panel

TNFRSF13B Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Primary Immunodeficiency Panel Panel

Finland.

By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK

More info about this panel

BREAST AND OVARIAN CANCER NGS PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL BREAST AND OVARIAN CANCER NGS PANEL that also includes the following genes: BLM BRCA1 BRCA2 STK11 EPCAM TP53 WRN CDH1 PSMC3IP TNFRSF13B

More info about this panel

COMMON VARIABLE IMMUNODEFICIENCY DUE TO TNFR DEFICIENCY Panel

Spain.

By Laboratorio de Genetica Clinica SL COMMON VARIABLE IMMUNODEFICIENCY DUE TO TNFR DEFICIENCY that also includes the following genes: TNFRSF13C TNFRSF13B

More info about this panel

COMMON VARIABLE IMMUNODEFICIENCY NGS PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL COMMON VARIABLE IMMUNODEFICIENCY NGS PANEL that also includes the following genes: IKZF1 CD19 CD81 LRBA TNFRSF13C TNFRSF13B IRF2BP2 CR2 ICOS IL21

More info about this panel

Common Variable Immune Deficiency Type 2 , Sequencing TNFRSF13B Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the TNFRSF13B gene.

More info about this panel

Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes Panel

Spain.

By Reference Laboratory Genetics Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes that also includes the following genes: CXCL12 SH2D1A BTK STAT1 STAT3 TGFB1 TNFRSF4 CD40 CD40LG AICDA

More info about this panel


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