TNFRSF13B gene related symptoms and diseases
All the information presented here about the TNFRSF13B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to TNFRSF13B gene
| Symptoms // Phenotype | % Cases |
|---|---|
| IgA deficiency | Very Common - Between 80% and 100% cases |
| Immunodeficiency | Very Common - Between 80% and 100% cases |
| Autoimmunity | Very Common - Between 80% and 100% cases |
| Hepatomegaly | Common - Between 50% and 80% cases |
| IgG deficiency | Common - Between 50% and 80% cases |
Other less frequent symptoms and clinical features
Patients with TNFRSF13B gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Recurrent bronchitis
- IgM deficiency
- Diarrhea
- Conjunctivitis
- Recurrent bacterial infections
- Recurrent pneumonia
- Impaired T cell function
- Recurrent infection of the gastrointestinal tract
And 43 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to TNFRSF13B gene
Here you will find a list of rare diseases related to the TNFRSF13B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
COMMON VARIABLE IMMUNODEFICIENCY
Alternate names
COMMON VARIABLE IMMUNODEFICIENCY Is also known as primary antibody deficiency, cvid, antibody deficiency due to icos defect, idiopathic immunoglobulin deficiency, primary hypogammaglobulinemia
Description
Common variable immunodeficiency (CVID) comprises a heterogeneous group of diseases characterized by a significant hypogammaglobulinemia of unknown cause, failure to produce specific antibodies after immunizations and susceptibility to bacterial infections, predominantly caused by encapsulated bacteria.
Most common symptoms of COMMON VARIABLE IMMUNODEFICIENCY
- Hepatomegaly
- Diarrhea
- Splenomegaly
- Immunodeficiency
- Recurrent infections
More info about COMMON VARIABLE IMMUNODEFICIENCY
IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2
Alternate names
IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2 Is also known as immunoglobulin a, selective deficiency of, taci-related, iga, selective deficiency of, taci-related
Most common symptoms of IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2
- Immunodeficiency
- Autoimmunity
- IgA deficiency
- Recurrent sinopulmonary infections
- Recurrent infection of the gastrointestinal tract
More info about IMMUNOGLOBULIN A DEFICIENCY 2; IGAD2
IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2
Alternate names
IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2 Is also known as antibody deficiency due to taci defect, hypogammaglobulinemia due to taci deficiency
Most common symptoms of IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2
- Neoplasm
- Hepatomegaly
- Diarrhea
- Splenomegaly
- Immunodeficiency
More info about IMMUNODEFICIENCY, COMMON VARIABLE, 2; CVID2
SOURCES: OMIM
Search interest in TNFRSF13B
Potential gene panels for TNFRSF13B gene
Common Variable Immunodeficiency Syndrome (CVID): TNFRSF13B (TACI) (Full Gene Sequencing) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta
This panel specifically test the TNFRSF13B gene.
More info about this panel Canada.
Common Variable Immunodeficiency Syndrome (CVID): TNFRSF13B (TACI) (Known Mutation) Panel
Canada.
By Molecular Diagnostic Laboratory University of Alberta
This panel specifically test the TNFRSF13B gene.
More info about this panel Canada.
TNFRSF13B Sequencing Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the TNFRSF13B gene.
More info about this panel United States.
TNFRSF13B Deletion/duplication analysis Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the TNFRSF13B gene.
More info about this panel United States.
Tier 2: Hereditary Lymphoma and Immunodeficiency Panel Panel
United States.
By Genetic Services Laboratory University of Chicago Tier 2: Hereditary Lymphoma and Immunodeficiency Panel that also includes the following genes: BLM SH2D1A BRCA1 BRCA2 STXBP2 FAS CD27 FASLG WAS IKZF1
More info about this panel United States.
Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication Panel
United States.
By ARUP Laboratories, Molecular Genetics and Genomics Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication that also includes the following genes: SH2D1A BTK CD40 CD40LG UNG VAV1 AICDA BLNK CD19 CD79A
More info about this panel United States.
TACI-Associated Common Variable Immunodeficiency (TNFRSF13B) Sequencing Panel
United States.
By ARUP Laboratories, Molecular Genetics and Genomics
This panel specifically test the TNFRSF13B gene.
More info about this panel United States.
Immunoglobulin A deficiency (sequence analysis of TNFRSF13B gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the TNFRSF13B gene.
More info about this panel Portugal.
Immunodeficiency, common variable, 2 (sequence analysis of TNFRSF13B/TACI gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the TNFRSF13B gene.
More info about this panel Portugal.
Immunodeficiency, common variable, 2 (sequence analysis of TNFRSF13B/TACI gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the TNFRSF13B gene.
More info about this panel Portugal.
Common Variable Immune Deficiency/IgA Deficiency via TNFRSF13B Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the TNFRSF13B gene.
More info about this panel United States.
Hereditary kidney disorders - different panels Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8
More info about this panel Germany.
B cell pathology panel Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht B cell pathology panel that also includes the following genes: BTK CD40 CD40LG UNG AICDA BLNK CD19 CD79A CD79B CD81
More info about this panel Netherlands.
Immunodeficiency common variable type 2 Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the TNFRSF13B gene.
More info about this panel Germany.
CentoICU platinum plus Panel
Germany.
By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
New Born testing (CentoICU) Panel
Germany.
By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC
More info about this panel Germany.
Antibody deficiencies Panel Panel
Germany.
By CeGaT GmbH Antibody deficiencies Panel that also includes the following genes: BTK TCF3 TCF4 CD40 TNFSF12 CD40LG UNG AICDA BLNK RTEL1
More info about this panel Germany.
Common variable Immunodefiency Panel
Denmark.
By Department of Clinical Immunology Odense University Hospital
This panel specifically test the TNFRSF13B gene.
More info about this panel Denmark.
Invitae Common Variable Immunodeficiency Panel Panel
United States.
By Invitae Invitae Common Variable Immunodeficiency Panel that also includes the following genes: STAT3 CD27 TNFSF12 LRBA TNFRSF13C TNFRSF13B CR2 CTLA4 ICOS IL21
More info about this panel United States.
Invitae Monogenic Autoimmunity Panel Panel
United States.
By Invitae Invitae Monogenic Autoimmunity Panel that also includes the following genes: RMRP SH2D1A SLC7A7 BTK STAT1 STAT3 STAT5B STIM1 STX11 STXBP2
More info about this panel United States.
Invitae Primary Immunodeficiency Panel Panel
United States.
By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2
More info about this panel United States.
Common Variable Immunodeficiency: TNFRSF13B gene sequence analysis Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the TNFRSF13B gene.
More info about this panel Spain.
Common variable immunodeficiency Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Common variable immunodeficiency that also includes the following genes: CD19 CD81 TNFRSF13C TNFRSF13B CR2 ICOS IL21 MS4A1 NFKB1
More info about this panel Spain.
TNFRSF13B Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the TNFRSF13B gene.
More info about this panel United States.
Primary Immunodeficiency Panel Panel
Finland.
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panel Finland.
BREAST AND OVARIAN CANCER NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL BREAST AND OVARIAN CANCER NGS PANEL that also includes the following genes: BLM BRCA1 BRCA2 STK11 EPCAM TP53 WRN CDH1 PSMC3IP TNFRSF13B
More info about this panel Spain.
COMMON VARIABLE IMMUNODEFICIENCY DUE TO TNFR DEFICIENCY Panel
Spain.
By Laboratorio de Genetica Clinica SL COMMON VARIABLE IMMUNODEFICIENCY DUE TO TNFR DEFICIENCY that also includes the following genes: TNFRSF13C TNFRSF13B
More info about this panel Spain.
COMMON VARIABLE IMMUNODEFICIENCY NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL COMMON VARIABLE IMMUNODEFICIENCY NGS PANEL that also includes the following genes: IKZF1 CD19 CD81 LRBA TNFRSF13C TNFRSF13B IRF2BP2 CR2 ICOS IL21
More info about this panel Spain.
Common Variable Immune Deficiency Type 2 , Sequencing TNFRSF13B Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the TNFRSF13B gene.
More info about this panel Spain.
Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes Panel
Spain.
By Reference Laboratory Genetics Common Variable Immune Deficiency and Related Disorders, Panel Massive Sequencing (NGS) 41 Genes that also includes the following genes: CXCL12 SH2D1A BTK STAT1 STAT3 TGFB1 TNFRSF4 CD40 CD40LG AICDA
More info about this panel Spain.
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