NUMA1 gene related symptoms and diseases

All the information presented here about the NUMA1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to NUMA1 gene

Symptoms // Phenotype % Cases
Leukemia Very Common - Between 80% and 100% cases
Acute promyelocytic leukemia Very Common - Between 80% and 100% cases
Abnormal granulocytopoietic cell morphology Very Common - Between 80% and 100% cases

Rare diseases associated to NUMA1 gene

Here you will find a list of rare diseases related to the NUMA1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


ACUTE PROMYELOCYTIC LEUKEMIA


Alternate names

ACUTE PROMYELOCYTIC LEUKEMIA Is also known as acute myeloid leukemia with t(15;17)(q22;q12);(pml/raralpha) and variants, acute myeloblastic leukemia 3, apml, aml m3, aml with t(15;17)(q22;q12);(pml/raralpha) and variants, leukemia, acute promyelocytic

Description

Acute promyelocytic leukemia (APL) is an aggressive form of acute myeloid leukemia (AML; see this term), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells. APL manifests with easy bruising, hemorrhagic diathesis and fatigue.

Most common symptoms of ACUTE PROMYELOCYTIC LEUKEMIA

  • Leukemia
  • Acute promyelocytic leukemia
  • Abnormal granulocytopoietic cell morphology


More info about ACUTE PROMYELOCYTIC LEUKEMIA

SOURCES: OMIM ORPHANET MESH


Potential gene panels for NUMA1 gene

Leukemia, acute promyelocytic, NUMA/RARA type (sequence analysis of NUMA1 gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the NUMA1 gene.

More info about this panel

Leukemia, promyelocytic acute form Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the NUMA1 gene.

More info about this panel

NUMA1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the NUMA1 gene.

More info about this panel

Caris MI TumorSeek 592-Gene NGS Panel Panel

United States.

By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1

More info about this panel


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