MGMT gene related symptoms and diseases

All the information presented here about the MGMT gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to MGMT gene

Symptoms // Phenotype % Cases
Retinopathy Uncommon - Between 30% and 50% cases
Dry skin Uncommon - Between 30% and 50% cases
Nevus Uncommon - Between 30% and 50% cases
Abnormality of extrapyramidal motor function Uncommon - Between 30% and 50% cases
Abnormality of the hair Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with MGMT gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Melanoma
  • Freckling
  • Neoplasm of the pancreas
  • Abnormality of the lymphatic system
  • Neoplasm of the breast
  • Neoplasm of the stomach
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Rare diseases associated to MGMT gene

Here you will find a list of rare diseases related to the MGMT. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


GIANT CELL GLIOBLASTOMA



More info about GIANT CELL GLIOBLASTOMA

SOURCES: ORPHANET

FAMILIAL MELANOMA


Description

Familial melanoma (FM) is a rare inherited form of melanoma characterized by development of histologically confirmed melanoma in two first degrees relatives or more relatives in an affected family.

Most common symptoms of FAMILIAL MELANOMA

  • Retinopathy
  • Dry skin
  • Nevus
  • Abnormality of extrapyramidal motor function
  • Abnormality of the hair


More info about FAMILIAL MELANOMA

SOURCES: ORPHANET


Potential gene panels for MGMT gene

MGMT Promoter Methylation assay Panel

United States.

By UCSF Molecular Diagnostics Laboratory University of California, San Francisco

This panel specifically test the MGMT gene.

More info about this panel

HopeSeq Glioma Panel

United States.

By Clinical Molecular Diagnostic Laboratory City of Hope National Medical Center

This panel specifically test the MGMT gene.

More info about this panel

Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) Panel

Portugal.

By CGC Genetics Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) that also includes the following genes: IDH1 IDH2 MGMT

More info about this panel

Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) Panel

Portugal.

By CGC Genetics Glioma (methilation analysis of MGMT gene promoter and frequent mutations on IDH1 e IDH2 genes) that also includes the following genes: IDH1 IDH2 MGMT

More info about this panel

MGMT promoter methylation Panel

United States.

By Molecular Diagnostics Laboratory University of Toledo Medical Center

This panel specifically test the MGMT gene.

More info about this panel

MMR genes methylation analysis Panel

Germany.

By Centogene AG - the Rare Disease Company MMR genes methylation analysis that also includes the following genes: MGMT MLH1 MLH3 MSH2 MSH3 MSH6 PMS2

More info about this panel

Hereditary Cancer Syndrome: Sequencing Panel Panel

United States.

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Hereditary Cancer Syndrome: Sequencing Panel that also includes the following genes: BLM SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCA4 SMARCB1 STK11

More info about this panel

MGMT Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MGMT gene.

More info about this panel

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel

Melanoma: Gene Sequencing Panel Panel

Canada.

By CEN4GEN Institute for Genomics and Molecular Diagnostics Melanoma: Gene Sequencing Panel that also includes the following genes: BRCA1 TP53 WRN CDK4 CDKN2A KIT MGMT NRAS BAP1 PTEN

More info about this panel

Hereditary Cancer Syndrome: Gene Sequencing Panel Panel

Canada.

By CEN4GEN Institute for Genomics and Molecular Diagnostics Hereditary Cancer Syndrome: Gene Sequencing Panel that also includes the following genes: BLM SDHB SDHC SDHD BMPR1A BRCA1 BRCA2 SMARCA4 SMARCB1 STK11

More info about this panel


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