MEIOB gene related symptoms and diseases

All the information presented here about the MEIOB gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to MEIOB gene

Symptoms // Phenotype % Cases
Azoospermia Very Common - Between 80% and 100% cases
Infertility Uncommon - Between 30% and 50% cases
Decreased testicular size Uncommon - Between 30% and 50% cases
Increased circulating gonadotropin level Uncommon - Between 30% and 50% cases
Abnormal spermatogenesis Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with MEIOB gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Obstructive azoospermia
  • Non-obstructive azoospermia
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Rare diseases associated to MEIOB gene

Here you will find a list of rare diseases related to the MEIOB. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


SPERMATOGENIC FAILURE 22; SPGF22


Most common symptoms of SPERMATOGENIC FAILURE 22; SPGF22

  • Infertility
  • Azoospermia


More info about SPERMATOGENIC FAILURE 22; SPGF22

SOURCES: OMIM

MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION


Description

Male infertility with azoospermia or oligospermia due to single gene mutation is a rare, genetic male infertility due to sperm disorder characterized by the absence of a measurable amount of spermatozoa in the ejaculate (azoospermia), or a number of sperm in the ejaculate inferior to 15 million/mL (oligozoospermia), resulting from a mutation in a single gene known to cause azoo- or oligo-spermia. Sperm morphology may be normal.

Most common symptoms of MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION

  • Decreased testicular size
  • Azoospermia
  • Increased circulating gonadotropin level
  • Abnormal spermatogenesis
  • Obstructive azoospermia


More info about MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION

SOURCES: ORPHANET


Potential gene panels for MEIOB gene

MEIOB Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MEIOB gene.

More info about this panel


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