MEIOB gene related symptoms and diseases
All the information presented here about the MEIOB gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to MEIOB gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Azoospermia | Very Common - Between 80% and 100% cases |
| Infertility | Uncommon - Between 30% and 50% cases |
| Decreased testicular size | Uncommon - Between 30% and 50% cases |
| Increased circulating gonadotropin level | Uncommon - Between 30% and 50% cases |
| Abnormal spermatogenesis | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with MEIOB gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Obstructive azoospermia
- Non-obstructive azoospermia
Rare diseases associated to MEIOB gene
Here you will find a list of rare diseases related to the MEIOB. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
SPERMATOGENIC FAILURE 22; SPGF22
Most common symptoms of SPERMATOGENIC FAILURE 22; SPGF22
- Infertility
- Azoospermia
More info about SPERMATOGENIC FAILURE 22; SPGF22
SOURCES: OMIM
MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
Description
Male infertility with azoospermia or oligospermia due to single gene mutation is a rare, genetic male infertility due to sperm disorder characterized by the absence of a measurable amount of spermatozoa in the ejaculate (azoospermia), or a number of sperm in the ejaculate inferior to 15 million/mL (oligozoospermia), resulting from a mutation in a single gene known to cause azoo- or oligo-spermia. Sperm morphology may be normal.
Most common symptoms of MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
- Decreased testicular size
- Azoospermia
- Increased circulating gonadotropin level
- Abnormal spermatogenesis
- Obstructive azoospermia
More info about MALE INFERTILITY WITH AZOOSPERMIA OR OLIGOZOOSPERMIA DUE TO SINGLE GENE MUTATION
SOURCES: ORPHANET
Search interest in MEIOB
Potential gene panels for MEIOB gene
MEIOB Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the MEIOB gene.
More info about this panel United States.
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