MAPK10 gene related symptoms and diseases
All the information presented here about the MAPK10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to MAPK10 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Intellectual disability | Very Common - Between 80% and 100% cases |
| Relative macrocephaly | Very Common - Between 80% and 100% cases |
| Generalized tonic-clonic seizures | Very Common - Between 80% and 100% cases |
| Falls | Very Common - Between 80% and 100% cases |
| Generalized myoclonic seizures | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with MAPK10 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Focal-onset seizure
- Epileptic encephalopathy
- Gingival overgrowth
- Intellectual disability, progressive
- Tented upper lip vermilion
- Atonic seizures
- Mental deterioration
- Abnormality of the periventricular white matter
And 31 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to MAPK10 gene
Here you will find a list of rare diseases related to the MAPK10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
LENNOX-GASTAUT SYNDROME
Description
Lennox-Gastaut syndrome (LGS) belongs to the group of severe childhood epileptic encephalopathies.
Most common symptoms of LENNOX-GASTAUT SYNDROME
- Intellectual disability
- Seizures
- Global developmental delay
- Ptosis
- Low-set ears
More info about LENNOX-GASTAUT SYNDROME
Search interest in MAPK10
Potential gene panels for MAPK10 gene
Ataxia Exome Panel Panel
United States.
By Genetic Services Laboratory University of Chicago Ataxia Exome Panel that also includes the following genes: BCS1L RTN2 SACS SCN1A SCN2A SCN8A SCO1 SDHA SDHD SLC16A2
More info about this panel United States.
MAPK10. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the MAPK10 gene.
More info about this panel Spain.
Epileptic encephalopathy, Lennox-Gastaut type (sequence analysis MAPK10 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the MAPK10 gene.
More info about this panel Portugal.
Epileptic encephalopathy (NGS panel for 67 genes) Panel
Portugal.
By CGC Genetics Epileptic encephalopathy (NGS panel for 67 genes) that also includes the following genes: SCN1A SCN1B SCN2A SCN8A SCN9A ST3GAL3 SLC2A1 SLC9A6 SPTAN1 CDKL5
More info about this panel Portugal.
Epileptic encephalopathy panel Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht Epileptic encephalopathy panel that also includes the following genes: SCN1A SCN1B SCN2A SCN8A SCN9A SLC2A1 SPTAN1 CDKL5 STXBP1 SYNGAP1
More info about this panel Netherlands.
Epileptic encephalopathy, Lennox-Gastaut type Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the MAPK10 gene.
More info about this panel Germany.
AllNeuro panel Panel
Germany.
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panel Germany.
Epileptic encephalopathy, Lennox Gastaut type Panel
Austria.
By Praxis fuer Humangenetik Wien
This panel specifically test the MAPK10 gene.
More info about this panel Austria.
Epileptic encephalopathy, Lennox Gastaut type Panel
Slovakia.
By MedGene
This panel specifically test the MAPK10 gene.
More info about this panel Slovakia.
Epileptic encephalopathies Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases Epileptic encephalopathies that also includes the following genes: SCN1A SCN2A SCN8A ST3GAL3 SLC2A1 SPTAN1 CDKL5 STXBP1 TREX1 WWOX
More info about this panel Spain.
Neurology: Sequencing Panel Panel
United States.
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Neurology: Sequencing Panel that also includes the following genes: SCN1A SCN1B SCN2A SCN8A SCN9A SHH ST3GAL3 ST3GAL5 STIL SIX3
More info about this panel United States.
Epilepsy NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Epilepsy NGS Panel that also includes the following genes: BCS1L SCN10A SCN1A SCN1B SCN2A SCN2B SCN3A SCN4A SCN4B SCN5A
More info about this panel United States.
Essential Epilepsy NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Essential Epilepsy NGS Panel that also includes the following genes: SCN1A SCN1B SCN2A SCN8A SCN9A ST3GAL3 ST3GAL5 SLC2A1 SLC35A2 SLC9A6
More info about this panel United States.
Comprehensive Epilepsy NGS Panel Panel
United States.
By Fulgent Genetics Fulgent Genetics Comprehensive Epilepsy NGS Panel that also includes the following genes: BCS1L RYR3 SCN10A SCN1A SCN1B SCN2A SCN2B SCN3A SCN4A SCN4B
More info about this panel United States.
MAPK10 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the MAPK10 gene.
More info about this panel United States.
Lennox-Gastaut syndrome Panel
Spain.
By Bioarray
This panel specifically test the MAPK10 gene.
More info about this panel Spain.
Lennox-Gastaut Syndrome, Sequencing MAPK10 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the MAPK10 gene.
More info about this panel Spain.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
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