LYZ gene related symptoms and diseases
All the information presented here about the LYZ gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LYZ gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Hearing impairment | Uncommon - Between 30% and 50% cases |
| Paresthesia | Uncommon - Between 30% and 50% cases |
| Renal amyloidosis | Uncommon - Between 30% and 50% cases |
| Albuminuria | Uncommon - Between 30% and 50% cases |
| Restrictive cardiomyopathy | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with LYZ gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Drusen
- Papilledema
- Optic neuropathy
- Amyloidosis
- Urticaria
- Cholestasis
- Nephrotic syndrome
- Polyneuropathy
And 18 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to LYZ gene
Here you will find a list of rare diseases related to the LYZ. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
AMYLOIDOSIS, FAMILIAL VISCERAL
Alternate names
AMYLOIDOSIS, FAMILIAL VISCERAL Is also known as german type amyloidosis, amyloidosis, systemic nonneuropathic, amyloidosis viii, amyloidosis, familial renal, ostertag type amyloidosis
Most common symptoms of AMYLOIDOSIS, FAMILIAL VISCERAL
- Hearing impairment
- Neoplasm
- Pain
- Hypertension
- Peripheral neuropathy
More info about AMYLOIDOSIS, FAMILIAL VISCERAL
ALYS AMYLOIDOSIS
Alternate names
ALYS AMYLOIDOSIS Is also known as familial amyloid nephropathy due to lysozyme variant, hereditary amyloid nephropathy due to lysozyme variant, lysozyme amyloidosis, familial renal amyloidosis due to lysozyme variant, hereditary renal amyloidosis due to lysozyme variant
Description
ALys amyloidosis is a rare, hereditary amyloidosis with primary renal involvement characterized by amyloid deposition in the kidney glomeruli and medulla, gastrointestinal tract, liver, spleen and slow disease progression. Symptoms and signs include nausea, vomiting, dyspepsia, gastritis, gastrointestinal hemorrhage, abdominal pain, hepatic rupture, sicca syndrome, purpura and petechiae, lymphadenopathy and renal dysfunction.
More info about ALYS AMYLOIDOSIS
SOURCES: ORPHANET
Search interest in LYZ
Potential gene panels for LYZ gene
LYZ-Related Familial Visceral Amyloidosis (sequence analysis of LYZ gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the LYZ gene.
More info about this panel Portugal.
Lysozyme amyloidosis (sequence analysis of LYZ) Panel
Portugal.
By CGC Genetics
This panel specifically test the LYZ gene.
More info about this panel Portugal.
Hereditary amyloidosis (NGS panel of 19 genes) Panel
Portugal.
By CGC Genetics Hereditary amyloidosis (NGS panel of 19 genes) that also includes the following genes: TACSTD2 TGFBI TNFRSF1A TTR NLRP3 IL31RA CST3 F10 FGA GSN
More info about this panel Portugal.
Hereditary amyloidosis (NGS panel of 19 genes) Panel
Portugal.
By CGC Genetics Hereditary amyloidosis (NGS panel of 19 genes) that also includes the following genes: TACSTD2 TGFBI TNFRSF1A TTR NLRP3 IL31RA CST3 F10 FGA GSN
More info about this panel Portugal.
AMYLOIDOSIS, FAMILIAL VISCERAL Panel
Germany.
By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders AMYLOIDOSIS, FAMILIAL VISCERAL that also includes the following genes: FGA LYZ
More info about this panel Germany.
Hereditary kidney disorders - different panels Panel
Germany.
By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8
More info about this panel Germany.
Hereditary Amyloidosis, gene sequencing panel Panel
United States.
By Molecular Diagnostics Laboratory University of Toledo Medical Center Hereditary Amyloidosis, gene sequencing panel that also includes the following genes: TTR FGA GSN LYZ B2M
More info about this panel United States.
Custom gene seqeuncing panel Panel
United States.
By Molecular Diagnostics Laboratory University of Toledo Medical Center Custom gene seqeuncing panel that also includes the following genes: RYR1 SDHA SDHC EPCAM TP53 TSC1 TSC2 TTR VHL CACNA1S
More info about this panel United States.
AllNeuro panel Panel
Germany.
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panel Germany.
Single gene testing LYZ Panel
Germany.
By CeGaT GmbH
This panel specifically test the LYZ gene.
More info about this panel Germany.
Amyloidosis Panel
Austria.
By Praxis fuer Humangenetik Wien
This panel specifically test the LYZ gene.
More info about this panel Austria.
Amyloidosis Panel
Slovakia.
By MedGene
This panel specifically test the LYZ gene.
More info about this panel Slovakia.
LYZ Gene, Full Gene Analysis Panel
United States.
By Mayo Clinic Genetic Testing Laboratories Mayo Clinic
This panel specifically test the LYZ gene.
More info about this panel United States.
LYZ Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LYZ gene.
More info about this panel United States.
KidneySeq - 264 Genes Panel
United States.
By Iowa Institute of Human Genetics University of Iowa KidneySeq - 264 Genes that also includes the following genes: ROBO2 CNNM2 SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8 BMP4 SEMA3E
More info about this panel United States.
AMYLOIDOSIS HEREDITARY NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL AMYLOIDOSIS HEREDITARY NGS PANEL that also includes the following genes: TACSTD2 TGFBI TNFRSF1A TTR NLRP3 IL31RA CST3 F10 FGA GSN
More info about this panel Spain.
AMYLOIDOSIS Panel
Spain.
By Laboratorio de Genetica Clinica SL AMYLOIDOSIS that also includes the following genes: TTR IL31RA FGA GSN LYZ OSMR B2M
More info about this panel Spain.
Familial Amyloidosis and Related Disorders , Panel Massive Sequencing (NGS) 8 Genes Panel
Spain.
By Reference Laboratory Genetics Familial Amyloidosis and Related Disorders , Panel Massive Sequencing (NGS) 8 Genes that also includes the following genes: TTR IL31RA FGA GSN LYZ OSMR B2M
More info about this panel Spain.
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like ARHGEF18 NDUFS7 RREB1 BRCA1 MYOT SNORD118 GEN1