LYZ gene related symptoms and diseases

All the information presented here about the LYZ gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to LYZ gene

Symptoms // Phenotype % Cases
Hearing impairment Uncommon - Between 30% and 50% cases
Paresthesia Uncommon - Between 30% and 50% cases
Renal amyloidosis Uncommon - Between 30% and 50% cases
Albuminuria Uncommon - Between 30% and 50% cases
Restrictive cardiomyopathy Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with LYZ gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Drusen
  • Papilledema
  • Optic neuropathy
  • Amyloidosis
  • Urticaria
  • Cholestasis
  • Nephrotic syndrome
  • Polyneuropathy

And 18 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to LYZ gene

Here you will find a list of rare diseases related to the LYZ. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


AMYLOIDOSIS, FAMILIAL VISCERAL


Alternate names

AMYLOIDOSIS, FAMILIAL VISCERAL Is also known as german type amyloidosis, amyloidosis, systemic nonneuropathic, amyloidosis viii, amyloidosis, familial renal, ostertag type amyloidosis

Most common symptoms of AMYLOIDOSIS, FAMILIAL VISCERAL

  • Hearing impairment
  • Neoplasm
  • Pain
  • Hypertension
  • Peripheral neuropathy


More info about AMYLOIDOSIS, FAMILIAL VISCERAL

SOURCES: ORPHANET OMIM

ALYS AMYLOIDOSIS


Alternate names

ALYS AMYLOIDOSIS Is also known as familial amyloid nephropathy due to lysozyme variant, hereditary amyloid nephropathy due to lysozyme variant, lysozyme amyloidosis, familial renal amyloidosis due to lysozyme variant, hereditary renal amyloidosis due to lysozyme variant

Description

ALys amyloidosis is a rare, hereditary amyloidosis with primary renal involvement characterized by amyloid deposition in the kidney glomeruli and medulla, gastrointestinal tract, liver, spleen and slow disease progression. Symptoms and signs include nausea, vomiting, dyspepsia, gastritis, gastrointestinal hemorrhage, abdominal pain, hepatic rupture, sicca syndrome, purpura and petechiae, lymphadenopathy and renal dysfunction.


More info about ALYS AMYLOIDOSIS

SOURCES: ORPHANET


Potential gene panels for LYZ gene

LYZ-Related Familial Visceral Amyloidosis (sequence analysis of LYZ gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the LYZ gene.

More info about this panel

Lysozyme amyloidosis (sequence analysis of LYZ) Panel

Portugal.

By CGC Genetics

This panel specifically test the LYZ gene.

More info about this panel

Hereditary amyloidosis (NGS panel of 19 genes) Panel

Portugal.

By CGC Genetics Hereditary amyloidosis (NGS panel of 19 genes) that also includes the following genes: TACSTD2 TGFBI TNFRSF1A TTR NLRP3 IL31RA CST3 F10 FGA GSN

More info about this panel

Hereditary amyloidosis (NGS panel of 19 genes) Panel

Portugal.

By CGC Genetics Hereditary amyloidosis (NGS panel of 19 genes) that also includes the following genes: TACSTD2 TGFBI TNFRSF1A TTR NLRP3 IL31RA CST3 F10 FGA GSN

More info about this panel

AMYLOIDOSIS, FAMILIAL VISCERAL Panel

Germany.

By Laboratory for Molecular Diagnostics Center for Nephrology and Metabolic Disorders AMYLOIDOSIS, FAMILIAL VISCERAL that also includes the following genes: FGA LYZ

More info about this panel

Hereditary kidney disorders - different panels Panel

Germany.

By Institute of Human Genetics Uniklinik RWTH Aachen Hereditary kidney disorders - different panels that also includes the following genes: BCS1L ROBO2 CNNM2 CFB SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8

More info about this panel

Hereditary Amyloidosis, gene sequencing panel Panel

United States.

By Molecular Diagnostics Laboratory University of Toledo Medical Center Hereditary Amyloidosis, gene sequencing panel that also includes the following genes: TTR FGA GSN LYZ B2M

More info about this panel

Custom gene seqeuncing panel Panel

United States.

By Molecular Diagnostics Laboratory University of Toledo Medical Center Custom gene seqeuncing panel that also includes the following genes: RYR1 SDHA SDHC EPCAM TP53 TSC1 TSC2 TTR VHL CACNA1S

More info about this panel

AllNeuro panel Panel

Germany.

By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1

More info about this panel

Single gene testing LYZ Panel

Germany.

By CeGaT GmbH

This panel specifically test the LYZ gene.

More info about this panel

Amyloidosis Panel

Austria.

By Praxis fuer Humangenetik Wien

This panel specifically test the LYZ gene.

More info about this panel

Amyloidosis Panel

Slovakia.

By MedGene

This panel specifically test the LYZ gene.

More info about this panel

LYZ Gene, Full Gene Analysis Panel

United States.

By Mayo Clinic Genetic Testing Laboratories Mayo Clinic

This panel specifically test the LYZ gene.

More info about this panel

LYZ Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the LYZ gene.

More info about this panel

KidneySeq - 264 Genes Panel

United States.

By Iowa Institute of Human Genetics University of Iowa KidneySeq - 264 Genes that also includes the following genes: ROBO2 CNNM2 SALL1 ATXN10 SCNN1A SCNN1B SCNN1G SDCCAG8 BMP4 SEMA3E

More info about this panel

AMYLOIDOSIS HEREDITARY NGS PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL AMYLOIDOSIS HEREDITARY NGS PANEL that also includes the following genes: TACSTD2 TGFBI TNFRSF1A TTR NLRP3 IL31RA CST3 F10 FGA GSN

More info about this panel

AMYLOIDOSIS Panel

Spain.

By Laboratorio de Genetica Clinica SL AMYLOIDOSIS that also includes the following genes: TTR IL31RA FGA GSN LYZ OSMR B2M

More info about this panel

Familial Amyloidosis and Related Disorders , Panel Massive Sequencing (NGS) 8 Genes Panel

Spain.

By Reference Laboratory Genetics Familial Amyloidosis and Related Disorders , Panel Massive Sequencing (NGS) 8 Genes that also includes the following genes: TTR IL31RA FGA GSN LYZ OSMR B2M

More info about this panel


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