LIPH gene related symptoms and diseases

All the information presented here about the LIPH gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to LIPH gene

Symptoms // Phenotype % Cases
Hyperhidrosis Very Common - Between 80% and 100% cases
Palmoplantar hyperkeratosis Common - Between 50% and 80% cases
Sparse hair Common - Between 50% and 80% cases
Hypotrichosis Common - Between 50% and 80% cases
Sparse and thin eyebrow Common - Between 50% and 80% cases

Other less frequent symptoms and clinical features

Patients with LIPH gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Sparse eyelashes
  • Sparse body hair
  • Woolly hair
  • Hypotrichosis of the scalp
  • Hyperkeratosis
  • Brittle hair
  • Not very common - Between 30% and 50% cases

  • Alopecia
  • Coarse hair

And 26 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to LIPH gene

Here you will find a list of rare diseases related to the LIPH. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


HYPOTRICHOSIS SIMPLEX


Alternate names

HYPOTRICHOSIS SIMPLEX Is also known as hhs, hereditary hypotrichosis simplex, hts, hypotrichosis simplex, generalized, hereditary

Description

Hypotrichosis simplex (HS) or hereditary hypotrichosis simplex (HHS) is characterized by reduced pilosity over the scalp and body (with sparse, thin, and short hair) in the absence of other anomalies.

Most common symptoms of HYPOTRICHOSIS SIMPLEX

  • Alopecia
  • Hyperhidrosis
  • Sparse hair
  • Hypotrichosis
  • Sparse and thin eyebrow


More info about HYPOTRICHOSIS SIMPLEX

SOURCES: ORPHANET OMIM

HYPOTRICHOSIS 7; HYPT7


Alternate names

HYPOTRICHOSIS 7; HYPT7 Is also known as hypotrichosis, localized, autosomal recessive 2, ah, hypotrichosis, total, mari type, hypotrichosis, autosomal recessive, lah2

Most common symptoms of HYPOTRICHOSIS 7; HYPT7

  • Hyperhidrosis
  • Hyperkeratosis
  • Abnormality of the nervous system
  • Sparse hair
  • Papule


More info about HYPOTRICHOSIS 7; HYPT7

SOURCES: MESH OMIM

WOOLLY HAIR


Alternate names

WOOLLY HAIR Is also known as wooly hair, familial woolly hair syndrome, hereditary woolly hair syndrome, familial wooly hair syndrome, hereditary wooly hair syndrome

Description

Woolly hair is a rare congenital abnormality of the structure of the scalp hair marked by extreme kinkiness of the hair.

Most common symptoms of WOOLLY HAIR

  • Strabismus
  • Cataract
  • Hyperhidrosis
  • Hyperkeratosis
  • Nevus


More info about WOOLLY HAIR

SOURCES: OMIM ORPHANET


Potential gene panels for LIPH gene

Hypotrichosis (NGS panel of 10 genes) Panel

Portugal.

By CGC Genetics Hypotrichosis (NGS panel of 10 genes) that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR

More info about this panel

Hypotrichosis (NGS panel of 10 genes) Panel

Portugal.

By CGC Genetics Hypotrichosis (NGS panel of 10 genes) that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR

More info about this panel

Hypotrichosis Comprehensive panel Panel

United States.

By Connective Tissue Gene Tests Hypotrichosis Comprehensive panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR

More info about this panel

Hypotrichosis NGS panel Panel

United States.

By Connective Tissue Gene Tests Hypotrichosis NGS panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR

More info about this panel

Hypotrichosis Deletion / Duplication panel Panel

United States.

By Connective Tissue Gene Tests Hypotrichosis Deletion / Duplication panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR

More info about this panel

Hypotrichosis type 7 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the LIPH gene.

More info about this panel

Nonsyndromic hypotrichosis panel Panel

Germany.

By Centogene AG - the Rare Disease Company Nonsyndromic hypotrichosis panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 HR

More info about this panel

Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel Panel

Germany.

By CeGaT GmbH Ectodermal dysplasia (including hypotrichosis and hypoplastic hair) Panel that also includes the following genes: BCS1L SNRPE SOX18 ST14 TRPS1 IFT122 WNT10A EDARADD SHOC2 LPAR6

More info about this panel

Pan-Ethnic Carrier Screen: Gene Sequencing Panel Panel

United States.

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Pan-Ethnic Carrier Screen: Gene Sequencing Panel that also includes the following genes: RMRP BCS1L RS1 SACS BLM SGCA SGCB SGCG SGSH SLC12A6

More info about this panel

LIPH Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the LIPH gene.

More info about this panel

HYPOTRICHOSIS SIMPLEX Panel

Spain.

By Laboratorio de Genetica Clinica SL HYPOTRICHOSIS SIMPLEX that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 LIPH DSG4 KRT71 KRT74 KRT25

More info about this panel

Woolly hair Panel

Spain.

By Laboratorio de Genetica Clinica SL Woolly hair that also includes the following genes: LPAR6 LIPH KRT71 KRT74 KRT25

More info about this panel

Woolly hair/Hypothricosis Simplex: NGS Panel Panel

Spain.

By Laboratorio de Genetica Clinica SL Woolly hair/Hypothricosis Simplex: NGS Panel that also includes the following genes: RPL21 SNRPE LPAR6 APCDD1 CDSN LIPH DSG4 KRT71 KRT74 KRT25

More info about this panel

Hypotricosis , Panel Massive Sequencing (NGS) 8 Genes Panel

Spain.

By Reference Laboratory Genetics Hypotricosis , Panel Massive Sequencing (NGS) 8 Genes that also includes the following genes: RPL21 LPAR6 APCDD1 CDSN LIPH DSG4 KRT74 HR

More info about this panel

Pan-Ethnic Carrier Screen: Full Gene Sequencing and SMA Analysis Panel

Canada.

By CEN4GEN Institute for Genomics and Molecular Diagnostics Pan-Ethnic Carrier Screen: Full Gene Sequencing and SMA Analysis that also includes the following genes: RMRP BCS1L SACS BLM SGCA SGCB SGCG SGSH SLC12A6 SLC17A5

More info about this panel


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