LCT gene related symptoms and diseases
All the information presented here about the LCT gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to LCT gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Diarrhea | Very Common - Between 80% and 100% cases |
| Carious teeth | Very Common - Between 80% and 100% cases |
| Metabolic acidosis | Very Common - Between 80% and 100% cases |
| Dehydration | Very Common - Between 80% and 100% cases |
| Atherosclerosis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with LCT gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Fructose intolerance
- Lactose intolerance
- Decreased small intestinal mucosa lactase activity
Rare diseases associated to LCT gene
Here you will find a list of rare diseases related to the LCT. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CONGENITAL LACTASE DEFICIENCY
Alternate names
CONGENITAL LACTASE DEFICIENCY Is also known as disaccharide intolerance ii, alactasia, congenital
Description
Congenital lactase deficiency is a rare severe gastrointestinal disorder in newborns primarily reported in Finland and characterized clinically by watery diarrhea on feeding with breast-milk or lactose-containing formula.
Most common symptoms of CONGENITAL LACTASE DEFICIENCY
- Diarrhea
- Carious teeth
- Metabolic acidosis
- Dehydration
- Atherosclerosis
More info about CONGENITAL LACTASE DEFICIENCY
Search interest in LCT
Potential gene panels for LCT gene
LCT. Detection of the mutation c.4170T>A (p.Tyr1390Ter) by sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the LCT gene.
More info about this panel Spain.
LCT. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the LCT gene.
More info about this panel Spain.
Congenital Diarrhea Seq Analysis Panel
United States.
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Congenital Diarrhea Seq Analysis that also includes the following genes: SAR1B SI SKIV2L SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3 CFTR
More info about this panel United States.
Congenital Diarrhea Del/Dup Panel Panel
United States.
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Congenital Diarrhea Del/Dup Panel that also includes the following genes: SAR1B SI SKIV2L SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3 CFTR
More info about this panel United States.
Congenital Diarrhea Seq + Del/Dup Panel Panel
United States.
By Division of Genomic Diagnostics The Children's Hospital of Philadelphia Congenital Diarrhea Seq + Del/Dup Panel that also includes the following genes: SAR1B SI SKIV2L SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3 CFTR
More info about this panel United States.
Congenital lactase deficiency (sequence analysis of LCT gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the LCT gene.
More info about this panel Portugal.
Lactase deficiency, congenital Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the LCT gene.
More info about this panel Germany.
Congenital lactase deficiency Panel
Germany.
By bio.logis Center for Human Genetics Diagnosticum
This panel specifically test the LCT gene.
More info about this panel Germany.
Lactose Intolerance, Adult Type (LCT) Panel
Germany.
By MVZ Dortmund Dr. Eberhard & Partner
This panel specifically test the LCT gene.
More info about this panel Germany.
Lactase persistence: LCT gene -13910C/T polymorphism analysis Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the LCT gene.
More info about this panel Spain.
LCT Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the LCT gene.
More info about this panel United States.
Cholestasis Panel Panel
Finland.
By Blueprint Genetics Cholestasis Panel that also includes the following genes: SLC25A13 SMPD1 SPINT2 EPCAM TJP2 UGT1A1 VPS33B NEUROG3 LMF1 NPC2
More info about this panel Finland.
Congenital Diarrhea Panel Panel
Finland.
By Blueprint Genetics Congenital Diarrhea Panel that also includes the following genes: SAR1B SI SKIV2L SLC10A2 SLC5A1 SLC9A3 SPINT2 STX3 EPCAM NEUROG3
More info about this panel Finland.
Comprehensive Metabolism Panel Panel
Finland.
By Blueprint Genetics Comprehensive Metabolism Panel that also includes the following genes: BCS1L CNNM2 RYR1 CNNM4 SCN4A SEC23B SGSH SI SLC40A1 SLC12A3
More info about this panel Finland.
Congenital Mono- and Disaccharide Disorders Panel Panel
Finland.
By Blueprint Genetics Congenital Mono- and Disaccharide Disorders Panel that also includes the following genes: SI SLC2A1 SLC2A2 SLC5A1 GALE GALK1 GALT ALDOB LCT
More info about this panel Finland.
Lactase deficiency, congenital Panel
Spain.
By Bioarray
This panel specifically test the LCT gene.
More info about this panel Spain.
Congenital Lactase Deficiency , Sequencing LCT Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the LCT gene.
More info about this panel Spain.
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