KRT12 gene related symptoms and diseases

All the information presented here about the KRT12 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to KRT12 gene

Symptoms // Phenotype % Cases
Pain Very Common - Between 80% and 100% cases
Reduced visual acuity Very Common - Between 80% and 100% cases
Photophobia Very Common - Between 80% and 100% cases
Scarring Very Common - Between 80% and 100% cases
Corneal opacity Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with KRT12 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Astigmatism
  • Cutaneous photosensitivity
  • Corneal dystrophy
  • Epiphora
  • Blurred vision
  • Muscle fibrillation
  • Blepharospasm
  • Recurrent corneal erosions

And 3 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to KRT12 gene

Here you will find a list of rare diseases related to the KRT12. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


MEESMANN CORNEAL DYSTROPHY


Alternate names

MEESMANN CORNEAL DYSTROPHY Is also known as mecd, juvenile hereditary epithelial dystrophy of meesmann, meesmann corneal dystrophy, corneal dystrophy, meesmann epithelial, corneal dystrophy, juvenile epithelial, of meesmann

Description

Meesmann corneal dystrophy (MECD) is a rare form of superficial corneal dystrophy characterized by distinct tiny bubble-like, round-to-oval punctate bilateral opacities in the central corneal epithelium, and to a lesser extent in the peripheral cornea, with little impact on vision.

Most common symptoms of MEESMANN CORNEAL DYSTROPHY

  • Pain
  • Reduced visual acuity
  • Photophobia
  • Scarring
  • Corneal opacity


More info about MEESMANN CORNEAL DYSTROPHY

SOURCES: OMIM ORPHANET MESH


Potential gene panels for KRT12 gene

MitoMet®Plus aCGH Analysis Panel

United States.

By Baylor Miraca Genetics Laboratories MitoMet®Plus aCGH Analysis that also includes the following genes: RGS9 RHO GRK1 RLBP1 RNASEL BCS1L RP1 RP2 RP9 RPE65

More info about this panel

KRT12 Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the KRT12 gene.

More info about this panel

KRT12 Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the KRT12 gene.

More info about this panel

Corneal Dystrophies Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Corneal Dystrophies Sequencing Panel with CNV Detection that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI VSX1 OVOL2 SLC4A11 COL8A2 CYP4V2 ZNF469

More info about this panel

Meesmann Corneal Dystrophy (MCD) via KRT12 Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the KRT12 gene.

More info about this panel

Single gene testing KRT12 Panel

Germany.

By CeGaT GmbH

This panel specifically test the KRT12 gene.

More info about this panel

Corneal Dystrophy Panel

Estonia.

By Asper Biogene Asper Biogene LLC Corneal Dystrophy that also includes the following genes: SOD1 TACSTD2 TCF4 ZEB1 TGFBI VSX1 SLC4A11 COL17A1 COL8A2 CYP4V2

More info about this panel

Eye diseases comprehensive panel Panel

Estonia.

By Asper Biogene Asper Biogene LLC Eye diseases comprehensive panel that also includes the following genes: RGS9 RHO GRK1 RLBP1 ROM1 RP1 RP2 RP9 RPE65 RPGR

More info about this panel

Meesmann corneal dystrophy: KRT12 gene sequence analysis Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases

This panel specifically test the KRT12 gene.

More info about this panel

KRT12 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the KRT12 gene.

More info about this panel

Corneal Dystrophy Panel Panel

Finland.

By Blueprint Genetics Corneal Dystrophy Panel that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI OVOL2 SLC4A11 COL17A1 COL5A1 COL8A2 CYP4V2

More info about this panel

Meesmann Corneal Distrophy , Sequencing KRT12 Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the KRT12 gene.

More info about this panel

Corneal Dystrophy , Panel Massive Sequencing (NGS) 18 Genes Panel

Spain.

By Reference Laboratory Genetics Corneal Dystrophy , Panel Massive Sequencing (NGS) 18 Genes that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI VSX1 SLC4A11 COL5A1 COL8A2 CYP4V2 ZNF469

More info about this panel


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