KRT10 gene related symptoms and diseases
All the information presented here about the KRT10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to KRT10 gene
Symptoms // Phenotype | % Cases |
---|---|
Erythroderma | Common - Between 50% and 80% cases |
Ichthyosis | Common - Between 50% and 80% cases |
Palmoplantar hyperkeratosis | Common - Between 50% and 80% cases |
Congenital ichthyosiform erythroderma | Common - Between 50% and 80% cases |
Erythema | Common - Between 50% and 80% cases |
Other less frequent symptoms and clinical features
Patients with KRT10 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Hyperkeratosis
Not very common - Between 30% and 50% cases
- Palmoplantar keratoderma
- Congenital bullous ichthyosiform erythroderma
- Scaling skin
- Epidermal acanthosis
Rarely - Less than 30% cases
- Disseminated intravascular coagulation
- Generalized hyperkeratosis
- Hypernatremia
And 24 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to KRT10 gene
Here you will find a list of rare diseases related to the KRT10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
AUTOSOMAL DOMINANT EPIDERMOLYTIC ICHTHYOSIS
Alternate names
AUTOSOMAL DOMINANT EPIDERMOLYTIC ICHTHYOSIS Is also known as bullous congenital ichthyosiform erythroderma of brock, epidermolytic ichthyosis, bie, bullous congenital ichthyosiform erythroderma, ehk, bullous erythroderma ichthyosiformis congenita of brocq, bcie, bullous ichthyosiform erythroderma, ichthyosis hystrix brocq
Description
Epidermolytic ichthyosis (EI) is a rare keratinopathic ichthyosis (KPI; see this term), that is characterized by a blistering phenotype at birth which progressively becomes hyperkeratotic.
Most common symptoms of AUTOSOMAL DOMINANT EPIDERMOLYTIC ICHTHYOSIS
- Growth delay
- Hyperhidrosis
- Hyperkeratosis
- Weight loss
- Erythema
More info about AUTOSOMAL DOMINANT EPIDERMOLYTIC ICHTHYOSIS
CONGENITAL RETICULAR ICHTHYOSIFORM ERYTHRODERMA
Alternate names
CONGENITAL RETICULAR ICHTHYOSIFORM ERYTHRODERMA Is also known as iwc, crie, ichthyosis with confetti, ichthyosis variegata
Description
Congenital reticular ichthyosiform erythroderma (CRIE), also known as ichthyosis with confetti (IWC), is a rare skin condition characterized by slowly enlarging islands of normal skin surrounded by erythematous ichthyotic patches in a reticulated pattern. The condition starts in infancy as a lamellar ichthyosis, with small islands of normal skin resembling confetti appearing in late childhood and at puberty. Histopathologic findings include band-like parakeratosis, psoriasiform acanthosis, and vacuolization of keratinocytes with binucleated cells in the upper epidermis, sometimes associated with amyloid deposition in the dermis. Ultrastructural abnormalities include perinuclear shells formed from a network of fine filaments in the upper epidermis (summary by Krunic et al., 2003).
Most common symptoms of CONGENITAL RETICULAR ICHTHYOSIFORM ERYTHRODERMA
- Hyperkeratosis
- Erythema
- Ichthyosis
- Palmoplantar keratoderma
- Epidermal acanthosis
More info about CONGENITAL RETICULAR ICHTHYOSIFORM ERYTHRODERMA
ANNULAR EPIDERMOLYTIC ICHTHYOSIS
Alternate names
ANNULAR EPIDERMOLYTIC ICHTHYOSIS Is also known as ciehk, epidermolytic ichthyosis, annular, aei
Description
Annular epidermolytic ichthyosis (AEI) is a rare clinical variant of epidermolytic ichthyosis (EI; see this term) characterized by the presence of a blistering phenotype at birth and the development from early infancy of annular polycyclic erythematous scales on the trunk and extremities.
Most common symptoms of ANNULAR EPIDERMOLYTIC ICHTHYOSIS
- Hyperkeratosis
- Erythema
- Ichthyosis
- Palmoplantar hyperkeratosis
- Erythroderma
More info about ANNULAR EPIDERMOLYTIC ICHTHYOSIS
AUTOSOMAL RECESSIVE EPIDERMOLYTIC ICHTHYOSIS
Alternate names
AUTOSOMAL RECESSIVE EPIDERMOLYTIC ICHTHYOSIS Is also known as arei
More info about AUTOSOMAL RECESSIVE EPIDERMOLYTIC ICHTHYOSIS
SOURCES: ORPHANET
Search interest in KRT10
Potential gene panels for KRT10 gene
KRT10 Panel
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the KRT10 gene.
More info about this panelKRT10. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the KRT10 gene.
More info about this panelEpidermolytic hyperkeratosis (sequence analysis of KRT10 gene) Panel
By CGC Genetics
This panel specifically test the KRT10 gene.
More info about this panelEpidermolysis bullosa (NGS panel for 18 genes) Panel
By CGC Genetics Epidermolysis bullosa (NGS panel for 18 genes) that also includes the following genes: DST FERMT1 COL17A1 COL7A1 DSP EXPH5 ITGA3 ITGA6 ITGB4 KRT1
More info about this panelEpidermolysis Bullosa and Related Disorders Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Epidermolysis Bullosa and Related Disorders Sequencing Panel with CNV Detection that also includes the following genes: DST TGM5 FERMT1 COL17A1 COL7A1 DSP ITGA3 ITGA6 ITGB4 JUP
More info about this panelCongenital Ichthyosis and Related Disorders Sequencing Panel with CNV Detection Panel
By PreventionGenetics PreventionGenetics Congenital Ichthyosis and Related Disorders Sequencing Panel with CNV Detection that also includes the following genes: SLC27A4 ST14 TGM1 ALOXE3 ABCA12 CLDN1 POMP PNPLA1 ABHD5 LIPN
More info about this panelIchthyosis Deletion / Duplication panel Panel
By Connective Tissue Gene Tests Ichthyosis Deletion / Duplication panel that also includes the following genes: ST14 STS SULT2B1 TGM1 TGM5 ALOXE3 ABCA12 CASP14 CHST8 CDSN
More info about this panelIchthyosis NGS panel Panel
By Connective Tissue Gene Tests Ichthyosis NGS panel that also includes the following genes: ST14 STS SULT2B1 TGM1 TGM5 ALOXE3 ABCA12 CASP14 CHST8 CDSN
More info about this panelIchthyosis Comprehensive panel Panel
By Connective Tissue Gene Tests Ichthyosis Comprehensive panel that also includes the following genes: ST14 STS SULT2B1 TGM1 TGM5 ALOXE3 ABCA12 CASP14 CHST8 CDSN
More info about this panelEpidermolytic hyperkeratosis Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the KRT10 gene.
More info about this panelIchthyoses and related disorders of cornification Panel Panel
By CeGaT GmbH Ichthyoses and related disorders of cornification Panel that also includes the following genes: SLC27A4 SNAP29 ST14 STS TAT TGM1 TGM5 VPS33B ATP2C1 NSDHL
More info about this panelGenetic Epidermolyses and blistering disorders Panel Panel
By CeGaT GmbH Genetic Epidermolyses and blistering disorders Panel that also includes the following genes: DST FERMT1 COL17A1 COL7A1 DSP EXPH5 ITGA3 ITGA6 ITGB4 KRT1
More info about this panelKRT10 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the KRT10 gene.
More info about this panelIchthyosis Panel Panel
By Blueprint Genetics Ichthyosis Panel that also includes the following genes: SLC27A4 STS TGM1 ALOXE3 ABCA12 MBTPS2 SPINK5 MPLKIP CDSN SUMF1
More info about this panelBullous congenital ichthyosiform erythroderma Panel
By Bioarray
This panel specifically test the KRT10 gene.
More info about this panelICHTHYOSIFORM ERYTHRODERMA, BULLOUS CONGENITAL Panel
By Laboratorio de Genetica Clinica SL ICHTHYOSIFORM ERYTHRODERMA, BULLOUS CONGENITAL that also includes the following genes: KRT1 KRT10
More info about this panelICHTHYOSIS, EPIDERMOLYTIC Panel
By Laboratorio de Genetica Clinica SL ICHTHYOSIS, EPIDERMOLYTIC that also includes the following genes: KRT1 KRT10
More info about this panelEPIDERMOLISIS BULLOSA: NGS PANEL Panel
By Laboratorio de Genetica Clinica SL EPIDERMOLISIS BULLOSA: NGS PANEL that also includes the following genes: DST TGM5 FERMT1 COL17A1 COL7A1 KLHL24 DSP EXPH5 ITGA3 ITGA6
More info about this panelCongenital Ichthyosis and related disorders , Panel Massive Sequencing (NGS) 33 Genes Panel
By Reference Laboratory Genetics Congenital Ichthyosis and related disorders , Panel Massive Sequencing (NGS) 33 Genes that also includes the following genes: SLC27A4 SNAP29 ST14 STS TGM1 TGM5 ALOXE3 ABCA12 SPINK5 MPLKIP
More info about this panelPalmoplantar Keratoderma and Related Disorders , Panel Massive Sequencing (NGS) 6 Genes Panel
By Reference Laboratory Genetics Palmoplantar Keratoderma and Related Disorders , Panel Massive Sequencing (NGS) 6 Genes that also includes the following genes: TRPV3 AQP5 KRT1 KRT10 KRT16 KRT9
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