KLF6 gene related symptoms and diseases
All the information presented here about the KLF6 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to KLF6 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Neoplasm | Very Common - Between 80% and 100% cases |
| Carcinoma | Very Common - Between 80% and 100% cases |
| Neoplasm of the lung | Very Common - Between 80% and 100% cases |
| Neoplasm of the skin | Uncommon - Between 30% and 50% cases |
| Breast carcinoma | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with KLF6 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Prostate cancer
- Nephroblastoma
- Colon cancer
- Stomach cancer
- Gastritis
- Retinoblastoma
- Chronic atrophic gastritis
- Neoplasm of the stomach
And 2 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to KLF6 gene
Here you will find a list of rare diseases related to the KLF6. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
PROSTATE CANCER
Description
The prostate is the gland below a man's bladder that produces fluid for semen. Prostate cancer is common among older men. It is rare in men younger than 40. Risk factors for developing prostate cancer include being over 65 years of age, family history, and being African-American. Symptoms of prostate cancer may include Problems passing urine, such as pain, difficulty starting or stopping the stream, or dribbling Low back pain Pain with ejaculation To diagnose prostate cancer, you doctor may do a digital rectal exam to feel the prostate for lumps or anything unusual. You may also get a blood test for prostate-specific antigen (PSA). These tests are also used in prostate cancer screening, which looks for cancer before you have symptoms. If your results are abnormal, you may need more tests, such as an ultrasound, MRI, or biopsy. Treatment often depends on the stage of the cancer. How fast the cancer grows and how different it is from surrounding tissue helps determine the stage. Men with prostate cancer have many treatment options. The treatment that's best for one man may not be best for another. The options include watchful waiting, surgery, radiation therapy, hormone therapy, and chemotherapy. You may have a combination of treatments. NIH: National Cancer Institute
Most common symptoms of PROSTATE CANCER
- Neoplasm
- Carcinoma
- Neoplasm of the skin
- Breast carcinoma
- Neoplasm of the lung
More info about PROSTATE CANCER
SOURCES: OMIM
GASTRIC CANCER
Description
In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several genes may be associated with an increased risk of gastric cancer.Gastric cancer is a manifestation of a number of inherited cancer predisposition syndromes, including hereditary nonpolyposis colon cancer (HNPCC1; see {120435}), familial adenomatous polyposis (FAP ), Peutz-Jeghers syndrome (PJS ), Cowden disease (CD ), and the Li-Fraumeni syndrome (OMIM ). See also hereditary diffuse gastric cancer (HDGC ).Canedo et al. (2007) provided a review of genetic susceptibility to gastric cancer in patients infected with Helicobacter pylori (see {600263}).
Most common symptoms of GASTRIC CANCER
- Neoplasm
- Carcinoma
- Nephroblastoma
- Colon cancer
- Neoplasm of the lung
More info about GASTRIC CANCER
Search interest in KLF6
Potential gene panels for KLF6 gene
Gastric cancer, somatic Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the KLF6 gene.
More info about this panel Germany.
Prostate cancer, somatic Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the KLF6 gene.
More info about this panel Germany.
KLF6 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the KLF6 gene.
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
CEN4GEN Prostate cancer: Extended gene sequencing Panel Panel
Canada.
By CEN4GEN Institute for Genomics and Molecular Diagnostics CEN4GEN Prostate cancer: Extended gene sequencing Panel that also includes the following genes: SCN11A SPOP TBX20 MED12 TP53 NIPA2 PDZRN3 CDKN1B CDKN2A KLF6
More info about this panel Canada.
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