KERA gene related symptoms and diseases
All the information presented here about the KERA gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,ORPHANET,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to KERA gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Hypermetropia | Uncommon - Between 30% and 50% cases |
| Esotropia | Uncommon - Between 30% and 50% cases |
| Corneal arcus | Uncommon - Between 30% and 50% cases |
| Flat cornea | Uncommon - Between 30% and 50% cases |
| Accommodative esotropia | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with KERA gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Decreased corneal thickness
Rare diseases associated to KERA gene
Here you will find a list of rare diseases related to the KERA. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CORNEA PLANA 2, AUTOSOMAL RECESSIVE; CNA2
Description
Cornea plana is clinically characterized by reduced corneal curvature leading in most cases to hyperopia, hazy corneal limbus, and arcus lipoides at an early age. CNA2 is a severe form of the disorder, which is frequently associated with additional ocular manifestations (summary by Tahvanainen et al., 1996).For discussion of genetic heterogeneity of CNA, see CNA1 (OMIM ).
Most common symptoms of CORNEA PLANA 2, AUTOSOMAL RECESSIVE; CNA2
- Hypermetropia
- Esotropia
- Corneal arcus
- Flat cornea
- Accommodative esotropia
More info about CORNEA PLANA 2, AUTOSOMAL RECESSIVE; CNA2
CONGENITAL CORNEA PLANA
Search interest in KERA
Potential gene panels for KERA gene
Anterior segment defects Panel
Denmark.
By Medical Genetics Laboratory, Kennedy Center Juliane Marie Center, Rigshospitalet Anterior segment defects that also includes the following genes: PORCN B3GLCT COL4A1 CYP1B1 EYA1 FOXC1 FOXE3 KERA LAMB2 PAX2
More info about this panel Denmark.
Cornea plana 2, autosomal recessive (sequence analysis of KERA gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the KERA gene.
More info about this panel Portugal.
Cornea plana 2, autosomal recessive (sequence analysis of KERA gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the KERA gene.
More info about this panel Portugal.
Corneal Dystrophies Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Corneal Dystrophies Sequencing Panel with CNV Detection that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI VSX1 OVOL2 SLC4A11 COL8A2 CYP4V2 ZNF469
More info about this panel United States.
KERA Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the KERA gene.
More info about this panel United States.
Corneal Dystrophy Panel Panel
Finland.
By Blueprint Genetics Corneal Dystrophy Panel that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI OVOL2 SLC4A11 COL17A1 COL5A1 COL8A2 CYP4V2
More info about this panel Finland.
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like BARD1 LRPPRC SGSH SALL1 ZBTB16 KCNAB2 MYC