KERA gene related symptoms and diseases

All the information presented here about the KERA gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,ORPHANET,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to KERA gene

Symptoms // Phenotype % Cases
Hypermetropia Uncommon - Between 30% and 50% cases
Esotropia Uncommon - Between 30% and 50% cases
Corneal arcus Uncommon - Between 30% and 50% cases
Flat cornea Uncommon - Between 30% and 50% cases
Accommodative esotropia Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with KERA gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Decreased corneal thickness
Mendelian

Accelerate your rare disease diagnosis with us

Learn more

Rare diseases associated to KERA gene

Here you will find a list of rare diseases related to the KERA. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CORNEA PLANA 2, AUTOSOMAL RECESSIVE; CNA2


Description

Cornea plana is clinically characterized by reduced corneal curvature leading in most cases to hyperopia, hazy corneal limbus, and arcus lipoides at an early age. CNA2 is a severe form of the disorder, which is frequently associated with additional ocular manifestations (summary by Tahvanainen et al., 1996).For discussion of genetic heterogeneity of CNA, see CNA1 (OMIM ).

Most common symptoms of CORNEA PLANA 2, AUTOSOMAL RECESSIVE; CNA2

  • Hypermetropia
  • Esotropia
  • Corneal arcus
  • Flat cornea
  • Accommodative esotropia


More info about CORNEA PLANA 2, AUTOSOMAL RECESSIVE; CNA2

SOURCES: MESH OMIM

CONGENITAL CORNEA PLANA



More info about CONGENITAL CORNEA PLANA

SOURCES: ORPHANET


Potential gene panels for KERA gene

Anterior segment defects Panel

Denmark.

By Medical Genetics Laboratory, Kennedy Center Juliane Marie Center, Rigshospitalet Anterior segment defects that also includes the following genes: PORCN B3GLCT COL4A1 CYP1B1 EYA1 FOXC1 FOXE3 KERA LAMB2 PAX2

More info about this panel

Cornea plana 2, autosomal recessive (sequence analysis of KERA gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the KERA gene.

More info about this panel

Cornea plana 2, autosomal recessive (sequence analysis of KERA gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the KERA gene.

More info about this panel

Corneal Dystrophies Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Corneal Dystrophies Sequencing Panel with CNV Detection that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI VSX1 OVOL2 SLC4A11 COL8A2 CYP4V2 ZNF469

More info about this panel

KERA Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the KERA gene.

More info about this panel

Corneal Dystrophy Panel Panel

Finland.

By Blueprint Genetics Corneal Dystrophy Panel that also includes the following genes: TACSTD2 TCF4 ZEB1 TGFBI OVOL2 SLC4A11 COL17A1 COL5A1 COL8A2 CYP4V2

More info about this panel


If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like CACNA1G WASHC5 PHF6

Need help with a diagnosis?

Learn more about how to achieve it with Mendelian


Learn more