ITGAL gene related symptoms and diseases

All the information presented here about the ITGAL gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to ITGAL gene

Symptoms // Phenotype % Cases
Seizures Uncommon - Between 30% and 50% cases
Pericarditis Uncommon - Between 30% and 50% cases
Cerebral ischemia Uncommon - Between 30% and 50% cases
Myositis Uncommon - Between 30% and 50% cases
Raynaud phenomenon Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with ITGAL gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Gangrene
  • Pulmonary infiltrates
  • Pustule
  • Uveitis
  • Aseptic necrosis
  • Pulmonary embolism
  • Hemoptysis
  • Keratoconjunctivitis sicca

And 97 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to ITGAL gene

Here you will find a list of rare diseases related to the ITGAL. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


BEHÇET DISEASE


Alternate names

BEHÇET DISEASE Is also known as bd, behcet disease

Description

Behçet's disease (BD) is a chronic, relapsing, multisystemic vasculitis characterized by mucocutaneous lesions, as well as articular, vascular, ocular and central nervous system manifestations.

Most common symptoms of BEHÇET DISEASE

  • Seizures
  • Ataxia
  • Neoplasm
  • Pain
  • Cataract


More info about BEHÇET DISEASE

SOURCES: OMIM ORPHANET MESH

ACUTE PROMYELOCYTIC LEUKEMIA


Alternate names

ACUTE PROMYELOCYTIC LEUKEMIA Is also known as acute myeloid leukemia with t(15;17)(q22;q12);(pml/raralpha) and variants, acute myeloblastic leukemia 3, apml, aml m3, aml with t(15;17)(q22;q12);(pml/raralpha) and variants, leukemia, acute promyelocytic

Description

Acute promyelocytic leukemia (APL) is an aggressive form of acute myeloid leukemia (AML; see this term), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells. APL manifests with easy bruising, hemorrhagic diathesis and fatigue.

Most common symptoms of ACUTE PROMYELOCYTIC LEUKEMIA

  • Leukemia
  • Acute promyelocytic leukemia
  • Abnormal granulocytopoietic cell morphology


More info about ACUTE PROMYELOCYTIC LEUKEMIA

SOURCES: OMIM ORPHANET MESH


Potential gene panels for ITGAL gene

Neutrophil Antigen Genotyping Panel (includes HNA-1, 3, 4, 5) Panel

United States.

By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti Neutrophil Antigen Genotyping Panel (includes HNA-1, 3, 4, 5) that also includes the following genes: SLC44A2 CD177 FCGR3B ITGAL ITGAM

More info about this panel

ITGAL Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the ITGAL gene.

More info about this panel


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