ITGA2 gene related symptoms and diseases
All the information presented here about the ITGA2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,ORPHANET,HGNC,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to ITGA2 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Thrombocytopenia | Very Common - Between 80% and 100% cases |
| Bruising susceptibility | Uncommon - Between 30% and 50% cases |
| Abnormal bleeding | Uncommon - Between 30% and 50% cases |
| Prolonged bleeding time | Uncommon - Between 30% and 50% cases |
| Abnormal thrombocyte morphology | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with ITGA2 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Decreased platelet glycoprotein IIb-IIIa
- Purpura
- Petechiae
- Neonatal alloimmune thrombocytopenia
Rare diseases associated to ITGA2 gene
Here you will find a list of rare diseases related to the ITGA2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
BLEEDING DIATHESIS DUE TO INTEGRIN ALPHA2-BETA1 DEFICIENCY
Alternate names
BLEEDING DIATHESIS DUE TO INTEGRIN ALPHA2-BETA1 DEFICIENCY Is also known as glycoprotein ia deficiency, gp ia deficiency, collagen platelet receptor deficiency
Most common symptoms of BLEEDING DIATHESIS DUE TO INTEGRIN ALPHA2-BETA1 DEFICIENCY
- Thrombocytopenia
- Bruising susceptibility
- Abnormal bleeding
- Prolonged bleeding time
- Abnormal thrombocyte morphology
More info about BLEEDING DIATHESIS DUE TO INTEGRIN ALPHA2-BETA1 DEFICIENCY
FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA
Alternate names
FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA Is also known as nait
Description
Foetal/neonatal alloimmune thrombocytopaenia (NAIT) results from maternal alloimmunisation against foetal platelet antigens inherited from the father and different from those present in the mother, and usually presents as a severe isolated thrombocytopaenia in otherwise healthy newborns.
Most common symptoms of FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA
- Thrombocytopenia
- Purpura
- Petechiae
- Neonatal alloimmune thrombocytopenia
More info about FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA
SOURCES: ORPHANET
Search interest in ITGA2
Potential gene panels for ITGA2 gene
Platelet Disorders Panel
United States.
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Platelet Disorders that also includes the following genes: RUNX1 STIM1 TBXA2R TBXAS1 USF1 VPS33B VWF WAS GP6 HPS3
More info about this panel United States.
ITGA2 Panel
Germany.
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the ITGA2 gene.
More info about this panel Germany.
Bleeding Disorders Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Bleeding Disorders Sequencing Panel with CNV Detection that also includes the following genes: RUNX1 TBXA2R TBXAS1 VWF WAS ADAMTS13 ABCG5 ABCG8 GP6 HPS3
More info about this panel United States.
Platelet Function Disorder Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Platelet Function Disorder Sequencing Panel with CNV Detection that also includes the following genes: TBXA2R TBXAS1 GP6 HPS3 HPS4 CD36 HPS5 DTNBP1 P2RY12 HPS6
More info about this panel United States.
Glycoprotein Ia C807T polymorphism Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the ITGA2 gene.
More info about this panel Germany.
Glycoprotein 1a Deficiency (ITGA2) Panel
Germany.
By MVZ Dortmund Dr. Eberhard & Partner
This panel specifically test the ITGA2 gene.
More info about this panel Germany.
Platelet Antigen Genotyping Panel Panel
United States.
By BloodCenter of Wisconsin Diagnostic Laboratories BloodCenter of Wisconsin, part of Versiti Platelet Antigen Genotyping Panel that also includes the following genes: CD109 GP1BA ITGA2 ITGA2B ITGB3
More info about this panel United States.
ITGA2 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the ITGA2 gene.
More info about this panel United States.
Thrombocytopenia Panel Panel
Finland.
By Blueprint Genetics Thrombocytopenia Panel that also includes the following genes: RUNX1 SRC THBD WAS WIPF1 ADAMTS13 ABCG5 ABCG8 TUBB1 ACTN1
More info about this panel Finland.
Comprehensive Hematology Panel Panel
Finland.
By Blueprint Genetics Comprehensive Hematology Panel that also includes the following genes: RHAG RIT1 RPL11 RPL15 RPL35A RPL5 RPS10 RPS19 RPS24 RPS26
More info about this panel Finland.
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