INSL3 gene related symptoms and diseases
All the information presented here about the INSL3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to INSL3 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Cryptorchidism | Very Common - Between 80% and 100% cases |
| Hypogonadism | Very Common - Between 80% and 100% cases |
| Abnormality of the kidney | Very Common - Between 80% and 100% cases |
| Infertility | Very Common - Between 80% and 100% cases |
| Renal agenesis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with INSL3 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Azoospermia
- Bilateral cryptorchidism
- Unilateral cryptorchidism
- Delayed menarche
Rare diseases associated to INSL3 gene
Here you will find a list of rare diseases related to the INSL3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CRYPTORCHIDISM, UNILATERAL OR BILATERAL
Alternate names
CRYPTORCHIDISM, UNILATERAL OR BILATERAL Is also known as undescended testis
Description
Cryptorchidism, or failure of testicular descent, is a common human congenital abnormality with a multifactorial etiology that likely reflects the involvement of endocrine, environmental, and hereditary factors. Cryptorchidism can result in infertility and increases risk for testicular tumors. Testicular descent from abdomen to scrotum occurs in 2 distinct phases: the transabdominal phase and the inguinoscrotal phase (summary by Gorlov et al., 2002).
Most common symptoms of CRYPTORCHIDISM, UNILATERAL OR BILATERAL
- Cryptorchidism
- Hypogonadism
- Abnormality of the kidney
- Infertility
- Renal agenesis
More info about CRYPTORCHIDISM, UNILATERAL OR BILATERAL
SOURCES: OMIM
Search interest in INSL3
Potential gene panels for INSL3 gene
Male Infertility Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Male Infertility Sequencing Panel with CNV Detection that also includes the following genes: SEMA3A SEMA3E FOXL2 BRDT SOX10 SOX2 SOX3 SOX9 SRA1 SRD5A2
More info about this panel United States.
Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) and Infertility Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A SEMA3E BMP7 FOXL2 BRDT SOS1
More info about this panel United States.
Disorders of Sex Development (DSD) Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Disorders of Sex Development (DSD) Sequencing Panel with CNV Detection that also includes the following genes: ROR2 SALL1 BMP15 BMP4 SEMA3A BMP7 FOXL2 SOS1 SOX10 SOX2
More info about this panel United States.
Male Factor Infertility Panel
Estonia.
By Asper Biogene Asper Biogene LLC Male Factor Infertility that also includes the following genes: TEKT2 XIST USP26 PRDM9 RXFP2 RBMXL2 DDX25 CFTR UTP14C NLRP14
More info about this panel Estonia.
INSL3 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the INSL3 gene.
More info about this panel United States.
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