IL6 gene related symptoms and diseases

All the information presented here about the IL6 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to IL6 gene

Symptoms // Phenotype % Cases
Weight loss Uncommon - Between 30% and 50% cases
Neoplasm Uncommon - Between 30% and 50% cases
Hepatomegaly Uncommon - Between 30% and 50% cases
Splenomegaly Uncommon - Between 30% and 50% cases
Abnormality of the gastrointestinal tract Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with IL6 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Arthralgia
  • Abnormality of the liver
  • Hepatosplenomegaly
  • Skin rash
  • Lymphadenopathy
  • Abdominal pain
  • Diarrhea
  • Growth delay

And 168 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to IL6 gene

Here you will find a list of rare diseases related to the IL6. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


ARTERIOVENOUS MALFORMATIONS OF THE BRAIN


Alternate names

ARTERIOVENOUS MALFORMATIONS OF THE BRAIN Is also known as cerebral arteriovenous malformations, bavm

Most common symptoms of ARTERIOVENOUS MALFORMATIONS OF THE BRAIN

  • Seizures
  • Pain
  • Headache
  • Back pain
  • Abnormality of the cerebral vasculature


More info about ARTERIOVENOUS MALFORMATIONS OF THE BRAIN

SOURCES: ORPHANET MESH OMIM

INFLAMMATORY BOWEL DISEASE (CROHN DISEASE) 1; IBD1


Most common symptoms of INFLAMMATORY BOWEL DISEASE (CROHN DISEASE) 1; IBD1

  • Growth delay
  • Neoplasm
  • Diarrhea
  • Abdominal pain
  • Weight loss


More info about INFLAMMATORY BOWEL DISEASE (CROHN DISEASE) 1; IBD1

SOURCES: OMIM ORPHANET

WILSON DISEASE


Alternate names

WILSON DISEASE Is also known as wd, hepatolenticular degeneration, wnd

Description

Wilson disease is a very rare inherited multisystemic disease presenting non-specific neurological, hepatic, psychiatric or osseo-muscular manifestations due to excessive copper deposition in the body.

Most common symptoms of WILSON DISEASE

  • Intellectual disability
  • Growth delay
  • Neoplasm
  • Failure to thrive
  • Spasticity


More info about WILSON DISEASE

SOURCES: MESH OMIM ORPHANET

SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS


Alternate names

SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS Is also known as systemic-onset jia, systemic juvenile rheumatoid arthritis, still disease, systemic polyarthritis

Description

Systemic-onset juvenile idiopathic arthritis is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio.

Most common symptoms of SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS

  • Visual impairment
  • Hepatomegaly
  • Fever
  • Splenomegaly
  • Visual loss


More info about SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS

SOURCES: ORPHANET OMIM

KAPOSI SARCOMA


Alternate names

KAPOSI SARCOMA Is also known as multiple idiopathic pigmented hemangiosarcoma, susceptibility to

Description

Kaposi sarcoma (KS) is a rare human herpes virus 8 (HHV-8)-induced endothelial inflammatory neoplasm that develops is various clinically distinct settings, manifesting mostly as cutaneous lesions, or mucosal or visceral involvement.

Most common symptoms of KAPOSI SARCOMA

  • Neoplasm
  • Hypertension
  • Fever
  • Fatigue
  • Edema


More info about KAPOSI SARCOMA

SOURCES: OMIM ORPHANET

DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM


Alternate names

DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM Is also known as noninsulin-dependent diabetes mellitus, maturity-onset diabetes, diabetes mellitus, type ii, t2d

Most common symptoms of DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM

  • Diabetes mellitus
  • Type II diabetes mellitus
  • Insulin resistance
  • Type I diabetes mellitus
  • Hyperinsulinemia


More info about DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM

SOURCES: OMIM ORPHANET


Potential gene panels for IL6 gene

Crohn Disease Panel

Germany.

By Bioscientia GmbH Center for Human Genetics Crohn Disease that also includes the following genes: NOD2 IL6

More info about this panel

IL6 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the IL6 gene.

More info about this panel

OmniSeq Comprehensive Panel

United States.

By OmniSeq, Inc. OmniSeq Comprehensive that also includes the following genes: RHEB BCL9 ROS1 RPS6KB1 SF3B1 FOXL2 BRAF BRCA1 BRCA2 SMARCB1

More info about this panel

Inflammatory Bowel Disease (IBD) and Related Disorders , Panel Massive Sequencing (NGS) 46 Genes Panel

Spain.

By Reference Laboratory Genetics Inflammatory Bowel Disease (IBD) and Related Disorders , Panel Massive Sequencing (NGS) 46 Genes that also includes the following genes: SH2D1A STXBP2 TERC TERT TGFB1 TINF2 CD40LG WAS WIPF1 CARD9

More info about this panel


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