IL36RN gene related symptoms and diseases

All the information presented here about the IL36RN gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to IL36RN gene

Symptoms // Phenotype % Cases
Pustule Uncommon - Between 30% and 50% cases
Psoriasiform dermatitis Uncommon - Between 30% and 50% cases
Furrowed tongue Rare - less than 30% cases
Pain Rare - less than 30% cases
Oligoarthritis Rare - less than 30% cases

Other less frequent symptoms and clinical features

Patients with IL36RN gene alterations may also develop some of the following symptoms and phenotypes:
  • Rarely - Less than 30% cases

  • Geographic tongue
  • Palmoplantar pustulosis
  • Periostitis
  • Asthenia
  • Neutrophilia
  • Chills
  • Cholangitis
  • Muscle weakness

And 12 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to IL36RN gene

Here you will find a list of rare diseases related to the IL36RN. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


GENERALIZED PUSTULAR PSORIASIS


Alternate names

GENERALIZED PUSTULAR PSORIASIS Is also known as ditra, interleukin 36 receptor antagonist deficiency, acrodermatitis continua of hallopeau, generalized pustular psoriasis, psorp, gpp, palmoplantar pustulosis

Description

Generalized pustular psoriasis is a severe inflammatory skin disease that can be life-threatening and that is characterized by recurrent episodes of high fever, fatigue, episodic erythematous cutaneous eruptions with sterile cutaneous pustules formation on various parts of the body, and neutrophil leukocytosis.

Most common symptoms of GENERALIZED PUSTULAR PSORIASIS

  • Muscle weakness
  • Fever
  • Headache
  • Erythema
  • Skin rash


More info about GENERALIZED PUSTULAR PSORIASIS

SOURCES: OMIM ORPHANET

PUSTULOSIS PALMARIS ET PLANTARIS


Alternate names

PUSTULOSIS PALMARIS ET PLANTARIS Is also known as localized pustular psoriasis, lpp, ppp, palmoplantar pustulosis

Most common symptoms of PUSTULOSIS PALMARIS ET PLANTARIS

  • Pain
  • Pruritus
  • Psoriasiform dermatitis
  • Pustule


More info about PUSTULOSIS PALMARIS ET PLANTARIS

SOURCES: ORPHANET

ACRODERMATITIS CONTINUA OF HALLOPEAU



More info about ACRODERMATITIS CONTINUA OF HALLOPEAU

SOURCES: ORPHANET

DITRA


Alternate names

DITRA Is also known as deficiency of il-36r antagonist, deficiency of il-36ra


More info about DITRA

SOURCES: ORPHANET


Potential gene panels for IL36RN gene

IL36RN Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the IL36RN gene.

More info about this panel

Psoriasis, generalized pustular (sequence analysis of IL36RN gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the IL36RN gene.

More info about this panel

Periodic Fever Syndromes Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Periodic Fever Syndromes Sequencing Panel with CNV Detection that also includes the following genes: TNFAIP3 TNFRSF1A LPIN2 IL36RN NLRP3 CARD14 NLRP12 ELANE NOD2 MEFV

More info about this panel

DITRA via IL36RN Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the IL36RN gene.

More info about this panel

IL36RN Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht

This panel specifically test the IL36RN gene.

More info about this panel

Autoinflammatory panel Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht Autoinflammatory panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN NLRP3 NCSTN NLRP12 NLRP7 PSENEN NOD2

More info about this panel

Psoriasis, generalized pustular Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the IL36RN gene.

More info about this panel

Single gene testing IL36RN Panel

Germany.

By CeGaT GmbH

This panel specifically test the IL36RN gene.

More info about this panel

Autoinflammatory diseases Panel Panel

Germany.

By CeGaT GmbH Autoinflammatory diseases Panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN RBCK1 NLRP3 CARD14 NLRP12 SLC29A3 HFE

More info about this panel

Invitae Primary Immunodeficiency Panel Panel

United States.

By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2

More info about this panel

Invitae Autoinflammatory Syndromes Panel Panel

United States.

By Invitae Invitae Autoinflammatory Syndromes Panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN RBCK1 NLRP3 NLRC4 CARD14 TRNT1 ADA2

More info about this panel

IL36RN Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the IL36RN gene.

More info about this panel

Primary Immunodeficiency Panel Panel

Finland.

By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK

More info about this panel

Autoinflammatory Syndrome Panel Panel

Finland.

By Blueprint Genetics Autoinflammatory Syndrome Panel that also includes the following genes: TNFAIP3 TNFRSF1A TREX1 ACP5 NLRP1 LPIN2 IL36RN SAMHD1 NLRP3 NLRC4

More info about this panel

Generalized Pustular Psoriasis , Sequencing IL36RN Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the IL36RN gene.

More info about this panel


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