IL36RN gene related symptoms and diseases
All the information presented here about the IL36RN gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to IL36RN gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Pustule | Uncommon - Between 30% and 50% cases |
| Psoriasiform dermatitis | Uncommon - Between 30% and 50% cases |
| Furrowed tongue | Rare - less than 30% cases |
| Pain | Rare - less than 30% cases |
| Oligoarthritis | Rare - less than 30% cases |
Other less frequent symptoms and clinical features
Patients with IL36RN gene alterations may also develop some of the following symptoms and phenotypes:Rarely - Less than 30% cases
- Geographic tongue
- Palmoplantar pustulosis
- Periostitis
- Asthenia
- Neutrophilia
- Chills
- Cholangitis
- Muscle weakness
And 12 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to IL36RN gene
Here you will find a list of rare diseases related to the IL36RN. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
GENERALIZED PUSTULAR PSORIASIS
Alternate names
GENERALIZED PUSTULAR PSORIASIS Is also known as ditra, interleukin 36 receptor antagonist deficiency, acrodermatitis continua of hallopeau, generalized pustular psoriasis, psorp, gpp, palmoplantar pustulosis
Description
Generalized pustular psoriasis is a severe inflammatory skin disease that can be life-threatening and that is characterized by recurrent episodes of high fever, fatigue, episodic erythematous cutaneous eruptions with sterile cutaneous pustules formation on various parts of the body, and neutrophil leukocytosis.
Most common symptoms of GENERALIZED PUSTULAR PSORIASIS
- Muscle weakness
- Fever
- Headache
- Erythema
- Skin rash
More info about GENERALIZED PUSTULAR PSORIASIS
PUSTULOSIS PALMARIS ET PLANTARIS
Alternate names
PUSTULOSIS PALMARIS ET PLANTARIS Is also known as localized pustular psoriasis, lpp, ppp, palmoplantar pustulosis
Most common symptoms of PUSTULOSIS PALMARIS ET PLANTARIS
- Pain
- Pruritus
- Psoriasiform dermatitis
- Pustule
More info about PUSTULOSIS PALMARIS ET PLANTARIS
SOURCES: ORPHANET
ACRODERMATITIS CONTINUA OF HALLOPEAU
DITRA
Alternate names
DITRA Is also known as deficiency of il-36r antagonist, deficiency of il-36ra
More info about DITRA
SOURCES: ORPHANET
Search interest in IL36RN
Potential gene panels for IL36RN gene
IL36RN Panel
Germany.
By Institute for Human Genetics University Clinic Freiburg
This panel specifically test the IL36RN gene.
More info about this panel Germany.
Psoriasis, generalized pustular (sequence analysis of IL36RN gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the IL36RN gene.
More info about this panel Portugal.
Periodic Fever Syndromes Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Periodic Fever Syndromes Sequencing Panel with CNV Detection that also includes the following genes: TNFAIP3 TNFRSF1A LPIN2 IL36RN NLRP3 CARD14 NLRP12 ELANE NOD2 MEFV
More info about this panel United States.
DITRA via IL36RN Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the IL36RN gene.
More info about this panel United States.
IL36RN Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht
This panel specifically test the IL36RN gene.
More info about this panel Netherlands.
Autoinflammatory panel Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht Autoinflammatory panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN NLRP3 NCSTN NLRP12 NLRP7 PSENEN NOD2
More info about this panel Netherlands.
Psoriasis, generalized pustular Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the IL36RN gene.
More info about this panel Germany.
Single gene testing IL36RN Panel
Germany.
By CeGaT GmbH
This panel specifically test the IL36RN gene.
More info about this panel Germany.
Autoinflammatory diseases Panel Panel
Germany.
By CeGaT GmbH Autoinflammatory diseases Panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN RBCK1 NLRP3 CARD14 NLRP12 SLC29A3 HFE
More info about this panel Germany.
Invitae Primary Immunodeficiency Panel Panel
United States.
By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2
More info about this panel United States.
Invitae Autoinflammatory Syndromes Panel Panel
United States.
By Invitae Invitae Autoinflammatory Syndromes Panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN RBCK1 NLRP3 NLRC4 CARD14 TRNT1 ADA2
More info about this panel United States.
IL36RN Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the IL36RN gene.
More info about this panel United States.
Primary Immunodeficiency Panel Panel
Finland.
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panel Finland.
Autoinflammatory Syndrome Panel Panel
Finland.
By Blueprint Genetics Autoinflammatory Syndrome Panel that also includes the following genes: TNFAIP3 TNFRSF1A TREX1 ACP5 NLRP1 LPIN2 IL36RN SAMHD1 NLRP3 NLRC4
More info about this panel Finland.
Generalized Pustular Psoriasis , Sequencing IL36RN Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the IL36RN gene.
More info about this panel Spain.
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SLC12A5 CACNA1F ATP7B TMPRSS3 LRPPRC ALG8 CALM3