IKZF3 gene related symptoms and diseases
All the information presented here about the IKZF3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to IKZF3 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Neoplasm | Very Common - Between 80% and 100% cases |
| Rheumatoid arthritis | Very Common - Between 80% and 100% cases |
| Lung adenocarcinoma | Very Common - Between 80% and 100% cases |
| Lymphocytosis | Very Common - Between 80% and 100% cases |
| Cellular immunodeficiency | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with IKZF3 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Chronic lymphatic leukemia
- Lymphoproliferative disorder
- B-cell lymphoma
- Acute leukemia
- Hodgkin lymphoma
- Hyperthyroidism
- Systemic lupus erythematosus
- Anemia
And 10 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to IKZF3 gene
Here you will find a list of rare diseases related to the IKZF3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA
Alternate names
B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA Is also known as b-cll, small lymphocytic lymphoma, b-cell chronic lymphoid leukemia, leukemia, chronic lymphatic
Description
B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma (see this term), and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia (see these terms). The clinical course is extremely heterogeneous with survival ranging from a few months to several decades.
Most common symptoms of B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA
- Neoplasm
- Anemia
- Splenomegaly
- Recurrent infections
- Thrombocytopenia
More info about B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA
Search interest in IKZF3
Potential gene panels for IKZF3 gene
IKZF3 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the IKZF3 gene.
More info about this panel United States.
Focus::CLL™ NGS Panel Panel
United States.
By Cancer Genetics, Inc. Cancer Genetics, Inc. Focus::CLL™ NGS Panel that also includes the following genes: SF3B1 BRAF BTK MED12 TP53 TRAF2 XPO1 ZMYM3 IKZF3 CARD11
More info about this panel United States.
Focus::DLBCL&FL™ NGS Panel Panel
United States.
By Cancer Genetics, Inc. Cancer Genetics, Inc. Focus::DLBCL&FL™ NGS Panel that also includes the following genes: BCL6 SGK1 BRAF ARID1A BTK STAT3 STAT6 SYK TNFAIP3 FAS
More info about this panel United States.
Focus::Lymphoma™ NGS Panel Panel
United States.
By Cancer Genetics, Inc. Cancer Genetics, Inc. Focus::Lymphoma™ NGS Panel that also includes the following genes: BCL6 SGK1 BRAF ARID1A BTK STAT3 STAT6 SYK TNFAIP3 FAS
More info about this panel United States.
FoundationOne® Heme Panel
United States.
By Foundation Medicine, Inc. FoundationOne® Heme that also includes the following genes: BCL6 BCL7A ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1
More info about this panel United States.
Tempus xO assay Panel
United States.
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panel United States.
If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SOX9 PTPRC LAMB3 HBD MMACHC MTMR2 CSTB