IGHG1 gene related symptoms and diseases

All the information presented here about the IGHG1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to IGHG1 gene

Symptoms // Phenotype % Cases
Neoplasm Very Common - Between 80% and 100% cases
Neurodegeneration Uncommon - Between 30% and 50% cases
Enlarged ovaries Uncommon - Between 30% and 50% cases
Beta-cell dysfunction Uncommon - Between 30% and 50% cases
Anemia Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with IGHG1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Splenomegaly
  • Recurrent infections
  • Thrombocytopenia
  • Arthritis
  • Autoimmunity
  • Leukemia
  • Lymphadenopathy
  • Lymphoma

And 41 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to IGHG1 gene

Here you will find a list of rare diseases related to the IGHG1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


POLYCYSTIC OVARY SYNDROME 1; PCOS1


Alternate names

POLYCYSTIC OVARY SYNDROME 1; PCOS1 Is also known as pco, pco1, hyperandrogenemia, stein-leventhal syndrome, pcos

Description

a health problem that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels, and appearance

Most common symptoms of POLYCYSTIC OVARY SYNDROME 1; PCOS1

  • Neoplasm
  • Abnormality of metabolism/homeostasis
  • Obesity
  • Diabetes mellitus
  • Apnea


More info about POLYCYSTIC OVARY SYNDROME 1; PCOS1

SOURCES: OMIM MESH

B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA


Alternate names

B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA Is also known as b-cll, small lymphocytic lymphoma, b-cell chronic lymphoid leukemia, leukemia, chronic lymphatic

Description

B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma (see this term), and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia (see these terms). The clinical course is extremely heterogeneous with survival ranging from a few months to several decades.

Most common symptoms of B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA

  • Neoplasm
  • Anemia
  • Splenomegaly
  • Recurrent infections
  • Thrombocytopenia


More info about B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA

SOURCES: OMIM ORPHANET


Potential gene panels for IGHG1 gene

t(11;14)(IGH/BCL1) rearrangement Panel

Portugal.

By CGC Genetics t(11;14)(IGH/BCL1) rearrangement that also includes the following genes: CCND1 IGHG1

More info about this panel

t(14;18)(IGH/BCL2) rearrangement Panel

Portugal.

By CGC Genetics

This panel specifically test the IGHG1 gene.

More info about this panel


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