HOXD10 gene related symptoms and diseases
All the information presented here about the HOXD10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to HOXD10 gene
Symptoms // Phenotype | % Cases |
---|---|
Pain | Uncommon - Between 30% and 50% cases |
Flexion contracture | Uncommon - Between 30% and 50% cases |
Talipes equinovarus | Uncommon - Between 30% and 50% cases |
Arthritis | Uncommon - Between 30% and 50% cases |
Abnormality of the foot | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with HOXD10 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Talipes
- Rocker bottom foot
- Metatarsus adductus
- Short tibia
- Calcaneovalgus deformity
- Equinus calcaneus
Rare diseases associated to HOXD10 gene
Here you will find a list of rare diseases related to the HOXD10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
VERTICAL TALUS, CONGENITAL; CVT
Alternate names
VERTICAL TALUS, CONGENITAL; CVT Is also known as pes valgus, congenital convex, rocker-bottom foot
Description
Congenital vertical talus (CVT), also known as 'rocker-bottom foot' deformity, is a dislocation of the talonavicular joint characterized by vertical orientation of the talus with a rigid dorsal dislocation of the navicular, equinus deformity of the calcaneus, abduction deformity of the forefoot, and contracture of the soft tissues of the hind- and mid-foot. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity with familial occurrence (summary by Levinsohn et al., 2004). The condition is transmitted in an autosomal dominant pattern of inheritance, and sometimes shows incomplete penetrance and variable expressivity. There may be a broad spectrum of deformities, including flatfoot, talipes equinovarus (TEV or clubfoot), cavus foot, metatarsus adductus, and even hypoplasia of the tibia (summary by Dobbs et al., 2006).
Most common symptoms of VERTICAL TALUS, CONGENITAL; CVT
- Pain
- Flexion contracture
- Talipes equinovarus
- Arthritis
- Abnormality of the foot
More info about VERTICAL TALUS, CONGENITAL; CVT
CONGENITAL VERTICAL TALUS, UNILATERAL
CONGENITAL VERTICAL TALUS, BILATERAL
Search interest in HOXD10
Potential gene panels for HOXD10 gene
Charcot-Marie-Tooth (CMT) and Related Hereditary Neuropathies, PMP22 Deletion/Duplication with Reflex to Sequencing Panel Panel
By ARUP Laboratories, Molecular Genetics and Genomics Charcot-Marie-Tooth (CMT) and Related Hereditary Neuropathies, PMP22 Deletion/Duplication with Reflex to Sequencing Panel that also includes the following genes: SBF1 SCN9A SLC12A6 SOX10 ATL1 SPTLC1 SPTLC2 TFG YARS PRX
More info about this panelCharcot-Marie-Tooth (CMT) and Related Hereditary Neuropathies Panel, Sequencing Panel
By ARUP Laboratories, Molecular Genetics and Genomics Charcot-Marie-Tooth (CMT) and Related Hereditary Neuropathies Panel, Sequencing that also includes the following genes: SBF1 SCN9A SLC12A6 SOX10 ATL1 SPTLC1 SPTLC2 TFG YARS PRX
More info about this panelHereditary peripheral neuropathies, including Charcot-Marie-Tooth disease (NGS panel for 74 genes) Panel
By CGC Genetics Hereditary peripheral neuropathies, including Charcot-Marie-Tooth disease (NGS panel for 74 genes) that also includes the following genes: SBF1 SCN11A SCN9A DST SLC12A6 SOX10 ATL1 SPTLC1 SPTLC2 TWNK
More info about this panelCharcot-Marie-Tooth disease (NGS panel for 43 genes) Panel
By CGC Genetics Charcot-Marie-Tooth disease (NGS panel for 43 genes) that also includes the following genes: SBF1 YARS PRX GDAP1 TRIM2 KIF1B LITAF FIG4 MFN2 TRPV4
More info about this panelCongenital vertical talus (sequence analysis of HOXD10 gene) Panel
By CGC Genetics
This panel specifically test the HOXD10 gene.
More info about this panelCongenital vertical talus (sequence analysis of HOXD10 gene) Panel
By CGC Genetics
This panel specifically test the HOXD10 gene.
More info about this panelAllNeuro panel Panel
By Centogene AG - the Rare Disease Company AllNeuro panel that also includes the following genes: BCS1L ROR2 RPL10 BDNF RPS6KA3 RTN2 RYR1 SACS BIN1 SBF1
More info about this panelCharcot-Marie-Tooth and Sensory Neuropathies Panel Panel
By CeGaT GmbH Charcot-Marie-Tooth and Sensory Neuropathies Panel that also includes the following genes: SBF1 SCN10A SCN11A SCN9A DST SLC12A6 SOX10 ATL1 SPTLC1 SPTLC2
More info about this panelHereditary Neuropathies: Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Hereditary Neuropathies: Sequencing Panel that also includes the following genes: SACS SCN9A SLC12A6 SLC1A3 SPG11 ATL1 SPAST SPG7 SPTBN2 SPTLC1
More info about this panelHereditary Neuropathies: Deletion/Duplication Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Hereditary Neuropathies: Deletion/Duplication Panel that also includes the following genes: SACS SCN9A SLC12A6 SLC1A3 SPG11 ATL1 SPAST SPG7 SPTBN2 SPTLC1
More info about this panelIntellectual Disability NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Intellectual Disability NGS Panel that also includes the following genes: BCS1L RPS6KA3 SACS BIN1 SCN1A SCN8A SDCCAG8 SGCA SGSH ST3GAL3
More info about this panelHOXD10 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the HOXD10 gene.
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like BCL3 NSMF IKBKG ABCD4 CA5A ACKR1 ANGPTL3