GAB1 gene related symptoms and diseases

All the information presented here about the GAB1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to GAB1 gene

Symptoms // Phenotype % Cases
Neoplasm Uncommon - Between 30% and 50% cases
Oligomenorrhea Uncommon - Between 30% and 50% cases
Hearing impairment Uncommon - Between 30% and 50% cases
Beta-cell dysfunction Uncommon - Between 30% and 50% cases
Enlarged ovaries Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with GAB1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Conjunctival hyperemia
  • Hypopnea
  • Frontal balding
  • Enlarged polycystic ovaries
  • Prostate cancer
  • Menstrual irregularities
  • Abnormality of the ovary
  • Adrenal hyperplasia

And 21 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to GAB1 gene

Here you will find a list of rare diseases related to the GAB1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


POLYCYSTIC OVARY SYNDROME 1; PCOS1


Alternate names

POLYCYSTIC OVARY SYNDROME 1; PCOS1 Is also known as pco, pco1, hyperandrogenemia, stein-leventhal syndrome, pcos

Description

a health problem that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels, and appearance

Most common symptoms of POLYCYSTIC OVARY SYNDROME 1; PCOS1

  • Neoplasm
  • Abnormality of metabolism/homeostasis
  • Obesity
  • Diabetes mellitus
  • Apnea


More info about POLYCYSTIC OVARY SYNDROME 1; PCOS1

SOURCES: OMIM MESH

DEAFNESS, AUTOSOMAL RECESSIVE 26; DFNB26


Description

DFNB26 is characterized by prelingual severe to profound nonsyndromic hearing loss (Yousaf et al., 2018).

Most common symptoms of DEAFNESS, AUTOSOMAL RECESSIVE 26; DFNB26

  • Hearing impairment
  • Sensorineural hearing impairment


More info about DEAFNESS, AUTOSOMAL RECESSIVE 26; DFNB26

SOURCES: MESH OMIM


Potential gene panels for GAB1 gene

GAB1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the GAB1 gene.

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


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