DSPP gene related symptoms and diseases
All the information presented here about the DSPP gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to DSPP gene
Symptoms // Phenotype | % Cases |
---|---|
Dentinogenesis imperfecta | Common - Between 50% and 80% cases |
Periapical bone loss | Uncommon - Between 30% and 50% cases |
Dentinogenesis imperfecta limited to primary teeth | Uncommon - Between 30% and 50% cases |
Pulp stones | Uncommon - Between 30% and 50% cases |
Tinnitus | Rare - less than 30% cases |
Other less frequent symptoms and clinical features
Patients with DSPP gene alterations may also develop some of the following symptoms and phenotypes:Rarely - Less than 30% cases
- Bilateral sensorineural hearing impairment
- Shell teeth
- Periodontitis
- Sensorineural hearing impairment
- Hearing impairment
- Double tooth
- Obliteration of the pulp chamber
- Short dental roots
And 12 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to DSPP gene
Here you will find a list of rare diseases related to the DSPP. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
DENTIN DYSPLASIA TYPE II
Alternate names
DENTIN DYSPLASIA TYPE II Is also known as dtdp2, pulp stones, dd-ii, pulpal dysplasia, dentin dysplasia, shields type ii, anomalous dysplasia of dentin, coronal dentin dysplasia
Description
Dentin dysplasia type II (DD-II) is a rare mild form of dentin dysplasia (DD, see this term) characterized by normal tooth roots but abnormal primary dentition.
Most common symptoms of DENTIN DYSPLASIA TYPE II
- Dentinogenesis imperfecta
- Pulp stones
- Failure of eruption of permanent teeth
- Dentinogenesis imperfecta limited to primary teeth
More info about DENTIN DYSPLASIA TYPE II
DENTIN DYSPLASIA TYPE I
Alternate names
DENTIN DYSPLASIA TYPE I Is also known as dtdp1, dentin dysplasia, shields type i, dd-i, rootless teeth, radicular dentin dysplasia
Description
Dentin dysplasia type I (DD-I) is a rare form of dentin dysplasia (DD, see this term) characterized by sharp conical short roots or rootless teeth.
Most common symptoms of DENTIN DYSPLASIA TYPE I
- Carious teeth
- Delayed eruption of teeth
- Microdontia
- Increased bone mineral density
- Oligodontia
More info about DENTIN DYSPLASIA TYPE I
DENTINOGENESIS IMPERFECTA TYPE 2
Alternate names
DENTINOGENESIS IMPERFECTA TYPE 2 Is also known as capdepont teeth, opalescent dentin, dgi-ii, opalescent teeth without osteogenesis imperfecta, dentinogenesis imperfecta without osteogenesis imperfecta, di-2, dentinogenesis imperfecta, shields type 2, dentinogenesis imperfecta, shields type ii, dgi-2
Description
Dentinogenesis imperfecta type 2 (DGI-2) is a rare, severe form of dentinogenesis imperfecta (DGI, see this term) and is characterized by weakness and discoloration of all teeth.
Most common symptoms of DENTINOGENESIS IMPERFECTA TYPE 2
- Hearing impairment
- Sensorineural hearing impairment
- Dentinogenesis imperfecta
More info about DENTINOGENESIS IMPERFECTA TYPE 2
DENTINOGENESIS IMPERFECTA TYPE 3
Alternate names
DENTINOGENESIS IMPERFECTA TYPE 3 Is also known as dgi-iii, brandywine type dentinogenesis imperfecta, dentinogenesis imperfecta, shields type 3
Description
Dentinogenesis imperfecta type 3 (DGI-3) is a rare, severe form of dentinogenesis imperfecta (DGI, see this term) characterized by opalescent primary and permanent teeth, marked attrition, large pulp chambers, multiple pulp exposure and shell teeth radiographically (i.e. teeth which appear hollow due to dentin hypotrophy).
Most common symptoms of DENTINOGENESIS IMPERFECTA TYPE 3
- Periodontitis
- Dentinogenesis imperfecta
- Shell teeth
- Periapical bone loss
More info about DENTINOGENESIS IMPERFECTA TYPE 3
DEAFNESS, AUTOSOMAL DOMINANT 39, WITH DENTINOGENESIS IMPERFECTA 1
Alternate names
DEAFNESS, AUTOSOMAL DOMINANT 39, WITH DENTINOGENESIS IMPERFECTA 1 Is also known as dfna39/dgi1 syndrome, dfna39/dentinogenesis imperfecta 1 syndrome, dgi1/dfna39 syndrome
Most common symptoms of DEAFNESS, AUTOSOMAL DOMINANT 39, WITH DENTINOGENESIS IMPERFECTA 1
- Bilateral sensorineural hearing impairment
- Tinnitus
- High-frequency hearing impairment
- Dentinogenesis imperfecta
More info about DEAFNESS, AUTOSOMAL DOMINANT 39, WITH DENTINOGENESIS IMPERFECTA 1
Search interest in DSPP
Potential gene panels for DSPP gene
Hearing Loss Advanced Sequencing and CNV Evaluation Panel
By Athena Diagnostics Inc Hearing Loss Advanced Sequencing and CNV Evaluation that also includes the following genes: BCS1L ROR1 SALL1 SEMA3E SIX1 SIX5 SLC12A1 SLC19A2 SLC22A4 SNAI2
More info about this panelOtoSCOPE Panel
By Molecular Otolaryngology and Renal Research Laboratories University of Iowa Hospital and Clinics OtoSCOPE that also includes the following genes: ROR1 SIX1 SIX5 SLC22A4 SNAI2 SMPX SOX10 TBX1 TWNK TCOF1
More info about this panelHearing Loss Panel Panel
By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Hearing Loss Panel that also includes the following genes: RPS6KA3 SALL1 SEMA3E SIX1 SIX5 SLC19A2 SNAI2 SMPX SOX10 BTD
More info about this panelExpanded Hearing Loss Panel, Sequencing and Deletion/Duplication Panel
By ARUP Laboratories, Molecular Genetics and Genomics Expanded Hearing Loss Panel, Sequencing and Deletion/Duplication that also includes the following genes: SMPX TECTA TMPRSS3 USH1C USH2A CLRN1 WFS1 ESPN CDH23 ACTG1
More info about this panelDSPP. Complete sequencing Panel
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the DSPP gene.
More info about this panelNon syndromic deafness AD (NGS panel for 33 genes) Panel
By CGC Genetics Non syndromic deafness AD (NGS panel for 33 genes) that also includes the following genes: SIX1 TECTA TJP2 WFS1 ACTG1 DIAPH3 TMC1 TMC2 CCDC50 SLC17A8
More info about this panelSyndromic and non syndromic deafness (NGS panel for 127 genes) Panel
By CGC Genetics Syndromic and non syndromic deafness (NGS panel for 127 genes) that also includes the following genes: SEMA3E SIX1 SIX5 SLC12A1 SLC19A2 SNAI2 SMPX SOX10 TCOF1 TECTA
More info about this panelNon syndromic deafness AD, AR and XL (NGS panel for 79 genes) Panel
By CGC Genetics Non syndromic deafness AD, AR and XL (NGS panel for 79 genes) that also includes the following genes: SIX1 SLC12A1 SMPX TECTA TJP2 TMPRSS3 USH1C TSPEAR WFS1 ESPN
More info about this panelDentinogenesis Imperfecta (DGI) and Dentin Dysplasia (DD) via DSPP Gene Sequencing with CNV Detection Panel
By PreventionGenetics PreventionGenetics
This panel specifically test the DSPP gene.
More info about this panelAmelogenesis imperfecta and related disorders Deletion/ Duplication panel Panel
By Connective Tissue Gene Tests Amelogenesis imperfecta and related disorders Deletion/ Duplication panel that also includes the following genes: SLC24A4 SMOC2 FAM20A FAM83H ODAPH WDR72 DLX3 DSPP ENAM GPR68
More info about this panelAmelogenesis imperfecta and related disorders Comprehensive panel Panel
By Connective Tissue Gene Tests Amelogenesis imperfecta and related disorders Comprehensive panel that also includes the following genes: SLC24A4 SMOC2 FAM20A FAM83H ODAPH WDR72 DLX3 DSPP ENAM GPR68
More info about this panelAmelogenesis imperfecta and related disorders NGS panel Panel
By Connective Tissue Gene Tests Amelogenesis imperfecta and related disorders NGS panel that also includes the following genes: SLC24A4 SMOC2 FAM20A FAM83H ODAPH WDR72 DLX3 DSPP ENAM GPR68
More info about this panelDeafness, autosomal dominant type 36 Panel
By Centogene AG - the Rare Disease Company
This panel specifically test the DSPP gene.
More info about this panelHearing Loss, nonsyndromic, autosomal dominant and X-linked Panel Panel
By CeGaT GmbH Hearing Loss, nonsyndromic, autosomal dominant and X-linked Panel that also includes the following genes: SMPX TECTA TJP2 WFS1 ACTG1 DIAPH3 TMC1 TMC2 CCDC50 SLC17A8
More info about this panelUsher Syndrome Panel
By Asper Biogene Asper Biogene LLC Usher Syndrome that also includes the following genes: USH1C USH2A CLRN1 CDH23 PCDH15 ABHD12 USH1G WHRN ADGRV1 GIPC3
More info about this panelqGenEx Craniofacial Anomalies Panel
By Quantitative Genomic Medicine Laboratories, SL qGenEx Craniofacial Anomalies that also includes the following genes: RUNX2 SALL1 TSHZ1 BMP4 SEMA3E SF3B4 SH3BP2 SHH SIX1 SIX3
More info about this panelDentinogenesis imperfecta, type 1: DSPP gene sequence analysis. Panel
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the DSPP gene.
More info about this panelHearing Loss: Sequencing Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Hearing Loss: Sequencing Panel that also includes the following genes: RPS6KA3 SALL1 SIX1 SIX5 SMPX SOX10 BTD TCOF1 TECTA TIMM8A
More info about this panelHearing Loss: Deletion/Duplication Panel Panel
By EGL Genetic Diagnostics Eurofins Clinical Diagnostics Hearing Loss: Deletion/Duplication Panel that also includes the following genes: RPS6KA3 SALL1 SIX1 SMPX BTD TECTA TIMM8A TJP2 TMPRSS3 USH1C
More info about this panelAmelogenesis Imperfecta NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Amelogenesis Imperfecta NGS Panel that also includes the following genes: BMP1 SERPINH1 IFITM5 SP7 FKBP10 P3H1 COL1A2 FAM20A CRTAP FAM83H
More info about this panelHearing Loss NGS Panel Panel
By Fulgent Genetics Fulgent Genetics Hearing Loss NGS Panel that also includes the following genes: BCS1L SIX1 SNAI2 SMPX SOX10 TBL1X TCF21 TECTA TIMM8A TJP2
More info about this panelDSPP Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the DSPP gene.
More info about this panelComprehensive Hearing Loss and Deafness Panel Panel
By Blueprint Genetics Comprehensive Hearing Loss and Deafness Panel that also includes the following genes: BCS1L RPS6KA3 SALL1 SEMA3E SIX1 SIX5 SLC19A2 SNAI2 SMPX SOX10
More info about this panelNon-Syndromic Hearing Loss Panel Panel
By Blueprint Genetics Non-Syndromic Hearing Loss Panel that also includes the following genes: SIX1 SMPX TECTA TJP2 TMPRSS3 USH1C TSPEAR WBP2 WFS1 ESPN
More info about this panelAmelogenesis Imperfecta and Dentinogenesis Imperfecta Panel Panel
By Blueprint Genetics Amelogenesis Imperfecta and Dentinogenesis Imperfecta Panel that also includes the following genes: SLC24A4 FAM20A FAM83H ODAPH WDR72 DLX3 DSPP ENAM GPR68 AMELX
More info about this panelDentinogenesis imperfecta, Shields type II Panel
By Bioarray
This panel specifically test the DSPP gene.
More info about this panelOtogenetics Hearing Loss and Deafness Multi-Gene NGS Panel Panel
By Otogenetics Otogenetics Hearing Loss and Deafness Multi-Gene NGS Panel that also includes the following genes: BCS1L SIX1 SIX5 SNAI2 SMPX SOX2 TBL1X TCF21 TECTA TFCP2
More info about this panelDENTINOGENESIS IMPERFECTA Panel
By Laboratorio de Genetica Clinica SL
This panel specifically test the DSPP gene.
More info about this panelDEAFNESS, NONSYNDROMIC SENSORINEURAL (AUTOSOMAL DOMINANT) NGS PANEL Panel
By Laboratorio de Genetica Clinica SL DEAFNESS, NONSYNDROMIC SENSORINEURAL (AUTOSOMAL DOMINANT) NGS PANEL that also includes the following genes: SIX1 SMPX TECTA TJP2 WFS1 ACTG1 P2RX2 DIAPH3 OSBPL2 CD164
More info about this panelDentinogenesis Imperfecta, Sequencing DSPP Gene Panel
By Reference Laboratory Genetics
This panel specifically test the DSPP gene.
More info about this panelDentinogenesis Imperfecta, Panel Massive Sequencing (NGS) 4 Genes Panel
By Reference Laboratory Genetics Dentinogenesis Imperfecta, Panel Massive Sequencing (NGS) 4 Genes that also includes the following genes: WNT10A DSPP MSX1 PTH1R
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