DNAJC13 gene related symptoms and diseases
All the information presented here about the DNAJC13 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to DNAJC13 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Dysphagia | Very Common - Between 80% and 100% cases |
| Apathy | Very Common - Between 80% and 100% cases |
| Spastic/hyperactive bladder | Very Common - Between 80% and 100% cases |
| Orthostatic hypotension due to autonomic dysfunction | Very Common - Between 80% and 100% cases |
| Low frustration tolerance | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with DNAJC13 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Parkinsonism with favorable response to dopaminergic medication
- Hyposmia
- Shuffling gait
- Hypomimic face
- Visual hallucinations
- Chronic constipation
- Lewy bodies
- Resting tremor
And 21 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to DNAJC13 gene
Here you will find a list of rare diseases related to the DNAJC13. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
HEREDITARY LATE-ONSET PARKINSON DISEASE
Alternate names
HEREDITARY LATE-ONSET PARKINSON DISEASE Is also known as autosomal dominant late-onset parkinson disease, lopd
Description
Hereditary late-onset Parkinson disease (LOPD) is a form of Parkinson disease (PD), characterized by an age of onset of more than 50 years, tremor at rest, gait complaints and falls, bradykinesia, rigidity and painful cramps. Patients usually present a low risk of developing non motor symptoms, dystonia, dyskinesia and levodopa-induced dyskinesia (LID).
Most common symptoms of HEREDITARY LATE-ONSET PARKINSON DISEASE
- Dysphagia
- Dystonia
- Depressivity
- Dementia
- Cerebral cortical atrophy
More info about HEREDITARY LATE-ONSET PARKINSON DISEASE
SOURCES: ORPHANET
Search interest in DNAJC13
Potential gene panels for DNAJC13 gene
Parkinson Disease and Parkinsonism Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Parkinson Disease and Parkinsonism Sequencing Panel with CNV Detection that also includes the following genes: SLC20A2 SLC6A3 SNCA SNCB SPG11 SPR SYNJ1 TAF1 TARDBP TWNK
More info about this panel United States.
PARK21 Parkinson Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the DNAJC13 gene.
More info about this panel Germany.
Parkinson Syndrome, autosomal dominant Panel Panel
Germany.
By CeGaT GmbH Parkinson Syndrome, autosomal dominant Panel that also includes the following genes: SNCA VPS35 HTRA2 LRRK2 CHCHD2 DNAJC13 EIF4G1 GBA PRKAR1B RAB29
More info about this panel Germany.
Parkinson all Panel Panel
Germany.
By CeGaT GmbH Parkinson all Panel that also includes the following genes: ATXN2 SLC6A3 SNCA SPG11 SPR SYNJ1 TAF1 TH VPS35 FBXO7
More info about this panel Germany.
NGS panel - Parkinson Panel
Netherlands.
By Genome Diagnostics VU University Medical Center NGS panel - Parkinson that also includes the following genes: ATXN2 SLC18A2 SLC6A3 SNCA SPR SYNJ1 TAF1 TH GIGYF2 UCHL1
More info about this panel Netherlands.
DNAJC13 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the DNAJC13 gene.
More info about this panel United States.
PARKINSON NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL PARKINSON NGS PANEL that also includes the following genes: SLC6A3 SMPD1 SNCA SYNJ1 UCHL1 VPS35 FBXO7 HTRA2 PINK1 DNAJC6
More info about this panel Spain.
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