DNAJC13 gene related symptoms and diseases

All the information presented here about the DNAJC13 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to DNAJC13 gene

Symptoms // Phenotype % Cases
Dysphagia Very Common - Between 80% and 100% cases
Apathy Very Common - Between 80% and 100% cases
Spastic/hyperactive bladder Very Common - Between 80% and 100% cases
Orthostatic hypotension due to autonomic dysfunction Very Common - Between 80% and 100% cases
Low frustration tolerance Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with DNAJC13 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Parkinsonism with favorable response to dopaminergic medication
  • Hyposmia
  • Shuffling gait
  • Hypomimic face
  • Visual hallucinations
  • Chronic constipation
  • Lewy bodies
  • Resting tremor

And 21 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to DNAJC13 gene

Here you will find a list of rare diseases related to the DNAJC13. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


HEREDITARY LATE-ONSET PARKINSON DISEASE


Alternate names

HEREDITARY LATE-ONSET PARKINSON DISEASE Is also known as autosomal dominant late-onset parkinson disease, lopd

Description

Hereditary late-onset Parkinson disease (LOPD) is a form of Parkinson disease (PD), characterized by an age of onset of more than 50 years, tremor at rest, gait complaints and falls, bradykinesia, rigidity and painful cramps. Patients usually present a low risk of developing non motor symptoms, dystonia, dyskinesia and levodopa-induced dyskinesia (LID).

Most common symptoms of HEREDITARY LATE-ONSET PARKINSON DISEASE

  • Dysphagia
  • Dystonia
  • Depressivity
  • Dementia
  • Cerebral cortical atrophy


More info about HEREDITARY LATE-ONSET PARKINSON DISEASE

SOURCES: ORPHANET


Potential gene panels for DNAJC13 gene

Parkinson Disease and Parkinsonism Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Parkinson Disease and Parkinsonism Sequencing Panel with CNV Detection that also includes the following genes: SLC20A2 SLC6A3 SNCA SNCB SPG11 SPR SYNJ1 TAF1 TARDBP TWNK

More info about this panel

PARK21 Parkinson Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the DNAJC13 gene.

More info about this panel

Parkinson Syndrome, autosomal dominant Panel Panel

Germany.

By CeGaT GmbH Parkinson Syndrome, autosomal dominant Panel that also includes the following genes: SNCA VPS35 HTRA2 LRRK2 CHCHD2 DNAJC13 EIF4G1 GBA PRKAR1B RAB29

More info about this panel

Parkinson all Panel Panel

Germany.

By CeGaT GmbH Parkinson all Panel that also includes the following genes: ATXN2 SLC6A3 SNCA SPG11 SPR SYNJ1 TAF1 TH VPS35 FBXO7

More info about this panel

NGS panel - Parkinson Panel

Netherlands.

By Genome Diagnostics VU University Medical Center NGS panel - Parkinson that also includes the following genes: ATXN2 SLC18A2 SLC6A3 SNCA SPR SYNJ1 TAF1 TH GIGYF2 UCHL1

More info about this panel

DNAJC13 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the DNAJC13 gene.

More info about this panel

PARKINSON NGS PANEL Panel

Spain.

By Laboratorio de Genetica Clinica SL PARKINSON NGS PANEL that also includes the following genes: SLC6A3 SMPD1 SNCA SYNJ1 UCHL1 VPS35 FBXO7 HTRA2 PINK1 DNAJC6

More info about this panel


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