DLG4 gene related symptoms and diseases

All the information presented here about the DLG4 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to DLG4 gene

Symptoms // Phenotype % Cases
Polycystic ovaries Very Common - Between 80% and 100% cases
Glucose intolerance Very Common - Between 80% and 100% cases
Obesity Very Common - Between 80% and 100% cases
Diabetes mellitus Very Common - Between 80% and 100% cases
Type II diabetes mellitus Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with DLG4 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Hypoplastic toenails
  • Abnormality of dental morphology
  • Unilateral renal agenesis
  • Obsessive-compulsive behavior
  • Chronic otitis media
  • Nephritis
  • Abnormality of the voice
  • Portal hypertension

And 327 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to DLG4 gene

Here you will find a list of rare diseases related to the DLG4. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


POLYCYSTIC OVARY SYNDROME 1; PCOS1


Alternate names

POLYCYSTIC OVARY SYNDROME 1; PCOS1 Is also known as pco, pco1, hyperandrogenemia, stein-leventhal syndrome, pcos

Description

a health problem that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels, and appearance

Most common symptoms of POLYCYSTIC OVARY SYNDROME 1; PCOS1

  • Neoplasm
  • Abnormality of metabolism/homeostasis
  • Obesity
  • Diabetes mellitus
  • Apnea


More info about POLYCYSTIC OVARY SYNDROME 1; PCOS1

SOURCES: OMIM MESH

WILLIAMS SYNDROME


Alternate names

WILLIAMS SYNDROME Is also known as deletion 7q11.23, williams syndrome, williams-beuren syndrome, chromosome 7q11.23 deletion syndrome, 1.5- to 1.8-mb, wms, monosomy 7q11.23, ws

Description

Williams syndrome is a rare genetic multisystemic neurodevelopmental disorder characterized by a distinct facial appearance, cardiac anomalies (most frequently supravalvular aortic stenosis), cognitive and developmental abnormalities, and connective tissue abnormalities (such as joint laxity)

Most common symptoms of WILLIAMS SYNDROME

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


More info about WILLIAMS SYNDROME

SOURCES: OMIM ORPHANET MESH




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