CHI3L1 gene related symptoms and diseases

All the information presented here about the CHI3L1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to CHI3L1 gene

Symptoms // Phenotype % Cases
Intellectual disability Uncommon - Between 30% and 50% cases
Mania Uncommon - Between 30% and 50% cases
Bipolar affective disorder Uncommon - Between 30% and 50% cases
Delusions Uncommon - Between 30% and 50% cases
Preeclampsia Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with CHI3L1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Borderline personality disorder
  • Mood swings
  • Auditory hallucinations
  • Personality disorder
  • Alzheimer disease
  • Social and occupational deterioration
  • Dyspnea
  • Cough

And 23 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to CHI3L1 gene

Here you will find a list of rare diseases related to the CHI3L1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


SCHIZOPHRENIA; SCZD


Alternate names

SCHIZOPHRENIA; SCZD Is also known as schizophrenia with or without an affective disorder

Description

Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease (OMIM ). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity.Schizophrenia and bipolar disorder (see {125480}) are generally considered to be separate entities, but patients who exhibit multiple symptoms of both disorders are often given the hybrid diagnosis schizoaffective disorder (Blacker and Tsuang, 1992). Genetic Heterogeneity of Schizophrenia with or without an Affective DisorderSCZD4 (OMIM ) is associated with variation in the PRODH gene (OMIM ); SCZD9 (OMIM ) with variation in the DISC1 gene (OMIM ); SCZD15 (OMIM ) with variation in the SHANK3 gene (OMIM ); SCZD16 (OMIM ) with a chromosome duplication involving the VIPR2 gene (OMIM ); SCZD17 (see {614332}) with variation in the NRXN1 gene (OMIM ); SCZD18 (OMIM ) with variation in the SLC1A1 gene (OMIM ); and SCZD19 (OMIM ) with variation in the RBM12 gene (OMIM ).For associations pending confirmation, see MAPPING and MOLECULAR GENETICS.

Most common symptoms of SCHIZOPHRENIA; SCZD

  • Intellectual disability
  • Microcephaly
  • Behavioral abnormality
  • Depressivity
  • Dementia


More info about SCHIZOPHRENIA; SCZD

SOURCES: OMIM

ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 7; ASRT7


Description

Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006).For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see {600807}.

Most common symptoms of ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 7; ASRT7

  • Dyspnea
  • Cough
  • Asthma
  • Inflammatory abnormality of the skin
  • Wheezing


More info about ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 7; ASRT7

SOURCES: OMIM


Potential gene panels for CHI3L1 gene

CHI3L1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the CHI3L1 gene.

More info about this panel


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