CASP10 gene related symptoms and diseases
All the information presented here about the CASP10 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,OMIM,ORPHANET,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to CASP10 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Neoplasm | Common - Between 50% and 80% cases |
| Anemia | Uncommon - Between 30% and 50% cases |
| Antineutrophil antibody positivity | Uncommon - Between 30% and 50% cases |
| Follicular hyperplasia | Uncommon - Between 30% and 50% cases |
| Increased IgM level | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with CASP10 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Autoimmune neutropenia
- Increased IgG level
- Reduced delayed hypersensitivity
- Coombs-positive hemolytic anemia
- Rheumatoid factor positive
- Platelet antibody positive
- Decreased lymphocyte apoptosis
- Increased IgA level
And 62 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to CASP10 gene
Here you will find a list of rare diseases related to the CASP10. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IIA; ALPS2A
Alternate names
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IIA; ALPS2A Is also known as alps2, autoimmune lymphoproliferative syndrome, type ii
Most common symptoms of AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IIA; ALPS2A
- Anemia
- Hepatomegaly
- Fever
- Splenomegaly
- Thrombocytopenia
More info about AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IIA; ALPS2A
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME
Alternate names
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME Is also known as alps, autoimmune lymphoproliferative syndrome, type i, autosomal dominant, fas deficiency, canale-smith syndrome
Description
Autoimmune lymphoproliferative syndrome (ALPS) is a rare, inherited disorder characterized by non-malignant lymphoproliferation, multilineage cytopenias, and a lifelong increased risk of Hodgkin's and non-Hodgkin's lymphoma.
Most common symptoms of AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME
- Neoplasm
- Anemia
- Hepatomegaly
- Edema
- Splenomegaly
More info about AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME
NON-HODGKIN LYMPHOMA
Alternate names
NON-HODGKIN LYMPHOMA Is also known as nhl, non-hodgkin lymphoma
Description
Non-Hodgkin malignant lymphomas(NHL) is a heterogeneous group of malignant tumors of the lymphoid system.
Most common symptoms of NON-HODGKIN LYMPHOMA
- Neoplasm
- Leukemia
- Lymphoma
- Hodgkin lymphoma
- B-cell lymphoma
More info about NON-HODGKIN LYMPHOMA
GASTRIC CANCER
Description
In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several genes may be associated with an increased risk of gastric cancer.Gastric cancer is a manifestation of a number of inherited cancer predisposition syndromes, including hereditary nonpolyposis colon cancer (HNPCC1; see {120435}), familial adenomatous polyposis (FAP ), Peutz-Jeghers syndrome (PJS ), Cowden disease (CD ), and the Li-Fraumeni syndrome (OMIM ). See also hereditary diffuse gastric cancer (HDGC ).Canedo et al. (2007) provided a review of genetic susceptibility to gastric cancer in patients infected with Helicobacter pylori (see {600263}).
Most common symptoms of GASTRIC CANCER
- Neoplasm
- Carcinoma
- Nephroblastoma
- Colon cancer
- Neoplasm of the lung
More info about GASTRIC CANCER
Search interest in CASP10
Potential gene panels for CASP10 gene
CASP10 Sequencing Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the CASP10 gene.
More info about this panel United States.
Autoimmune Lymphoproliferative Syndrome Panel by next-generation sequencing (NGS) Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center Autoimmune Lymphoproliferative Syndrome Panel by next-generation sequencing (NGS) that also includes the following genes: FAS FASLG CASP10 CASP8 MAGT1 FADD ITK KRAS NRAS
More info about this panel United States.
Autoimmune Lymphoproliferative Syndrome Deletion/Duplication Panel Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center Autoimmune Lymphoproliferative Syndrome Deletion/Duplication Panel that also includes the following genes: FAS FASLG CASP10 CASP8 MAGT1 FADD ITK KRAS NRAS
More info about this panel United States.
CASP10 Deletion/duplication analysis Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the CASP10 gene.
More info about this panel United States.
Tier 2: Hereditary Lymphoma and Immunodeficiency Panel Panel
United States.
By Genetic Services Laboratory University of Chicago Tier 2: Hereditary Lymphoma and Immunodeficiency Panel that also includes the following genes: BLM SH2D1A BRCA1 BRCA2 STXBP2 FAS CD27 FASLG WAS IKZF1
More info about this panel United States.
CASP10. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the CASP10 gene.
More info about this panel Spain.
Autoimmune lymphoproliferative syndrome type II (sequence analysis of CASP10 gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the CASP10 gene.
More info about this panel Portugal.
Autoimmune Lymphoproliferative Syndrome/ALPS Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Autoimmune Lymphoproliferative Syndrome/ALPS Sequencing Panel with CNV Detection that also includes the following genes: SH2D1A STAT3 FAS FASLG CASP10 CASP8 LRBA CTLA4 MAGT1 FADD
More info about this panel United States.
CASP10 Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht
This panel specifically test the CASP10 gene.
More info about this panel Netherlands.
ALPS/autoimmunity panel Panel
Netherlands.
By Genome Diagnostics Laboratory University Medical Center Utrecht ALPS/autoimmunity panel that also includes the following genes: FAS FASLG ITCH CASP10 CASP8 LRBA FADD AIRE IL2RA FOXP3
More info about this panel Netherlands.
Autoimmune lymphoproliferative syndrome Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the CASP10 gene.
More info about this panel Germany.
Bone marrow failure syndromes with Leukemia Panel Panel
Germany.
By CeGaT GmbH Bone marrow failure syndromes with Leukemia Panel that also includes the following genes: RUNX1 CASP10 CEBPA GATA1 NBN
More info about this panel Germany.
Immune dysregulation Panel Panel
Germany.
By CeGaT GmbH Immune dysregulation Panel that also includes the following genes: SH2D1A STX11 STXBP2 FAS FASLG TREX1 ITCH CASP10 CASP8 CARD11
More info about this panel Germany.
Invitae Monogenic Autoimmunity Panel Panel
United States.
By Invitae Invitae Monogenic Autoimmunity Panel that also includes the following genes: RMRP SH2D1A SLC7A7 BTK STAT1 STAT3 STAT5B STIM1 STX11 STXBP2
More info about this panel United States.
Invitae Primary Immunodeficiency Panel Panel
United States.
By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2
More info about this panel United States.
CASP10 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the CASP10 gene.
More info about this panel United States.
Primary Immunodeficiency Panel Panel
Finland.
By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK
More info about this panel Finland.
Autoimmune lymphoproliferative syndrome type 2A Panel
Spain.
By Bioarray
This panel specifically test the CASP10 gene.
More info about this panel Spain.
LYMPHOPROLIFERATIVE SYNDROME, AUTOIMMUNE Panel
Spain.
By Laboratorio de Genetica Clinica SL LYMPHOPROLIFERATIVE SYNDROME, AUTOIMMUNE that also includes the following genes: FAS FASLG CASP10 CASP8 NRAS
More info about this panel Spain.
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME NGS PANEL Panel
Spain.
By Laboratorio de Genetica Clinica SL AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME NGS PANEL that also includes the following genes: SH2D1A STAT3 FAS FASLG CASP10 CASP8 CTLA4 MAGT1 FADD XIAP
More info about this panel Spain.
Autoimmune Lymphoproliferative Syndrome Type II, Sequencing CASP10 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the CASP10 gene.
More info about this panel Spain.
Autosomic Autoimmune Lymphoproliferative Syndrome , Panel Massive Sequencing (NGS) 10 Genes Panel
Spain.
By Reference Laboratory Genetics Autosomic Autoimmune Lymphoproliferative Syndrome , Panel Massive Sequencing (NGS) 10 Genes that also includes the following genes: FAS FASLG CASP10 CASP8 CTLA4 MAGT1 FADD ITK KRAS NRAS
More info about this panel Spain.
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