CARD14 gene related symptoms and diseases

All the information presented here about the CARD14 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to CARD14 gene

Symptoms // Phenotype % Cases
Parakeratosis Very Common - Between 80% and 100% cases
Ichthyosis Very Common - Between 80% and 100% cases
Orthokeratosis Very Common - Between 80% and 100% cases
Psoriasiform dermatitis Very Common - Between 80% and 100% cases
Scaling skin Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with CARD14 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Epidermal acanthosis
  • Hyperkeratosis
  • Not very common - Between 30% and 50% cases

  • Dermal atrophy
  • Inflammatory abnormality of the skin
  • Arthritis
  • Arthralgia
  • Subungual hyperkeratosis
  • Fever

And 23 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to CARD14 gene

Here you will find a list of rare diseases related to the CARD14. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


PITYRIASIS RUBRA PILARIS


Description

Pityriasis rubra pilaris is a rare chronic papulosquamous disorder of unknown etiology characterized by small follicular papules, scaly red-orange patches, and palmoplantar hyperkeratosis, which may progress to plaques or erythroderma. Although most of the cases are sporadic and acquired, a familial form of the disease exists.

Most common symptoms of PITYRIASIS RUBRA PILARIS

  • Neoplasm
  • Pain
  • Hyperkeratosis
  • Erythema
  • Papule


More info about PITYRIASIS RUBRA PILARIS

SOURCES: ORPHANET OMIM

PSORIASIS 2; PSORS2


Most common symptoms of PSORIASIS 2; PSORS2

  • Fever
  • Hyperkeratosis
  • Arthralgia
  • Arthritis
  • Ichthyosis


More info about PSORIASIS 2; PSORS2

SOURCES: OMIM


Potential gene panels for CARD14 gene

CARD14 Panel

Germany.

By Institute for Human Genetics University Clinic Freiburg

This panel specifically test the CARD14 gene.

More info about this panel

Psoriasis susceptibility 2 (sequence analysis of CARD14 gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the CARD14 gene.

More info about this panel

Familial Pityriasis Rubra Pilaris (PRP) via CARD14 Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the CARD14 gene.

More info about this panel

Periodic Fever Syndromes Sequencing Panel with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics Periodic Fever Syndromes Sequencing Panel with CNV Detection that also includes the following genes: TNFAIP3 TNFRSF1A LPIN2 IL36RN NLRP3 CARD14 NLRP12 ELANE NOD2 MEFV

More info about this panel

Pityriasis rubra pilaris Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the CARD14 gene.

More info about this panel

Psoriasis type 2 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the CARD14 gene.

More info about this panel

Ichthyoses and related disorders of cornification Panel Panel

Germany.

By CeGaT GmbH Ichthyoses and related disorders of cornification Panel that also includes the following genes: SLC27A4 SNAP29 ST14 STS TAT TGM1 TGM5 VPS33B ATP2C1 NSDHL

More info about this panel

Autoinflammatory diseases Panel Panel

Germany.

By CeGaT GmbH Autoinflammatory diseases Panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN RBCK1 NLRP3 CARD14 NLRP12 SLC29A3 HFE

More info about this panel

Invitae Primary Immunodeficiency Panel Panel

United States.

By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2

More info about this panel

Invitae Autoinflammatory Syndromes Panel Panel

United States.

By Invitae Invitae Autoinflammatory Syndromes Panel that also includes the following genes: SH3BP2 TNFRSF1A LPIN2 IL36RN RBCK1 NLRP3 NLRC4 CARD14 TRNT1 ADA2

More info about this panel

CARD14 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the CARD14 gene.

More info about this panel

Primary Immunodeficiency Panel Panel

Finland.

By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK

More info about this panel

Autoinflammatory Syndrome Panel Panel

Finland.

By Blueprint Genetics Autoinflammatory Syndrome Panel that also includes the following genes: TNFAIP3 TNFRSF1A TREX1 ACP5 NLRP1 LPIN2 IL36RN SAMHD1 NLRP3 NLRC4

More info about this panel


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