BCL2 gene related symptoms and diseases

All the information presented here about the BCL2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to BCL2 gene

Symptoms // Phenotype % Cases
Insulin resistance Uncommon - Between 30% and 50% cases
Neoplasm Uncommon - Between 30% and 50% cases
Glucose intolerance Uncommon - Between 30% and 50% cases
Lymphadenopathy Rare - less than 30% cases
Enlarged ovaries Rare - less than 30% cases

Other less frequent symptoms and clinical features

Patients with BCL2 gene alterations may also develop some of the following symptoms and phenotypes:
  • Rarely - Less than 30% cases

  • Beta-cell dysfunction
  • Fever
  • Fatigue
  • Diarrhea
  • Splenomegaly
  • Weight loss
  • Respiratory tract infection
  • Leukemia

And 39 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to BCL2 gene

Here you will find a list of rare diseases related to the BCL2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


POLYCYSTIC OVARY SYNDROME 1; PCOS1


Alternate names

POLYCYSTIC OVARY SYNDROME 1; PCOS1 Is also known as pco, pco1, hyperandrogenemia, stein-leventhal syndrome, pcos

Description

a health problem that can affect a woman's menstrual cycle, fertility, hormones, insulin production, heart, blood vessels, and appearance

Most common symptoms of POLYCYSTIC OVARY SYNDROME 1; PCOS1

  • Neoplasm
  • Abnormality of metabolism/homeostasis
  • Obesity
  • Diabetes mellitus
  • Apnea


More info about POLYCYSTIC OVARY SYNDROME 1; PCOS1

SOURCES: OMIM MESH

FOLLICULAR LYMPHOMA


Alternate names

FOLLICULAR LYMPHOMA Is also known as oncogene b-cell leukemia 2

Description

Follicular lymphoma is a form of non-Hodgkin lymphoma (see this term) characterized by a proliferation of B cells whose nodular structure of follicular architecture is preserved.

Most common symptoms of FOLLICULAR LYMPHOMA

  • Neoplasm
  • Fever
  • Fatigue
  • Diarrhea
  • Splenomegaly


More info about FOLLICULAR LYMPHOMA

SOURCES: OMIM ORPHANET

HIGH GRADE B-CELL LYMPHOMA WITH MYC AND/ OR BCL2 AND/OR BCL6 REARRANGEMENT



More info about HIGH GRADE B-CELL LYMPHOMA WITH MYC AND/ OR BCL2 AND/OR BCL6 REARRANGEMENT

SOURCES: ORPHANET

INTRAVASCULAR LARGE B-CELL LYMPHOMA


Alternate names

INTRAVASCULAR LARGE B-CELL LYMPHOMA Is also known as tappeiner-pfleger disease, angioendotheliomatosis proliferans systemisata, malignant angioendotheliomatosis, angiotropic large cell lymphoma, intravascular lymphomatosis

Description

Intravascular large B-cell lymphoma (IVLBCL) is a very rare form of diffuse large B-cell lymphoma (see this term) characterized by the selective growth of lymphoma cells within the lumina of small blood vessels (especially the capillaries) that most often presents with a wide range of clinical manifestations (as potentially any tissue can be involved), with patients from Western countries more frequently manifesting with neurological and cutaneous symptoms while patients from Asian countries more frequently displaying hepatosplenomegaly and thrombocytopenia. IVLBCL is characterized by an absence of lymphadenopathy, an aggressive clinical course and a poor prognosis.


More info about INTRAVASCULAR LARGE B-CELL LYMPHOMA

SOURCES: ORPHANET




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