ASPN gene related symptoms and diseases

All the information presented here about the ASPN gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to ASPN gene

Symptoms // Phenotype % Cases
Pain Uncommon - Between 30% and 50% cases
Back pain Uncommon - Between 30% and 50% cases
Vertebral fusion Uncommon - Between 30% and 50% cases
Low back pain Uncommon - Between 30% and 50% cases
Intervertebral disc degeneration Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with ASPN gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Sciatica
  • Arthralgia
  • Joint stiffness
  • Osteoarthritis of the first carpometacarpal joint
  • Osteoarthritis of the distal interphalangeal joint
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Rare diseases associated to ASPN gene

Here you will find a list of rare diseases related to the ASPN. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


INTERVERTEBRAL DISC DISEASE; IDD


Description

Lumbar disc disease is caused by degeneration of intervertebral discs of the lumbar spine. One of the most common musculoskeletal disorders, it has strong genetic determinants (Matsui et al., 1998; Battie et al., 1995; Sambrook et al., 1999).

Most common symptoms of INTERVERTEBRAL DISC DISEASE; IDD

  • Pain
  • Back pain
  • Vertebral fusion
  • Low back pain
  • Intervertebral disc degeneration


More info about INTERVERTEBRAL DISC DISEASE; IDD

SOURCES: OMIM MESH

OSTEOARTHRITIS SUSCEPTIBILITY 3; OS3


Alternate names

OSTEOARTHRITIS SUSCEPTIBILITY 3; OS3 Is also known as osteoarthritis of knee/hip

Most common symptoms of OSTEOARTHRITIS SUSCEPTIBILITY 3; OS3

  • Arthralgia
  • Joint stiffness
  • Osteoarthritis of the first carpometacarpal joint
  • Osteoarthritis of the distal interphalangeal joint


More info about OSTEOARTHRITIS SUSCEPTIBILITY 3; OS3

SOURCES: OMIM


Potential gene panels for ASPN gene

ASPN Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the ASPN gene.

More info about this panel


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