F13B gene related symptoms and diseases
All the information presented here about the F13B gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,NCBIGENE,ORPHANET,HGNC, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to F13B gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Bruising susceptibility | Very Common - Between 80% and 100% cases |
| Abnormal bleeding | Very Common - Between 80% and 100% cases |
| Ecchymosis | Very Common - Between 80% and 100% cases |
| Poor wound healing | Very Common - Between 80% and 100% cases |
| Prolonged bleeding after surgery | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with F13B gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Abnormal umbilical stump bleeding
- Reduced factor XIII activity
Not very common - Between 30% and 50% cases
- Decreased testicular size
- Epistaxis
- Spontaneous abortion
- Intracranial hemorrhage
- Menorrhagia
- Oligospermia
And 3 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to F13B gene
Here you will find a list of rare diseases related to the F13B. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
CONGENITAL FACTOR XIII DEFICIENCY
Alternate names
CONGENITAL FACTOR XIII DEFICIENCY Is also known as fibrin-stabilizing factor deficiency
Description
Congenital factor XIII deficiency is an inherited bleeding disorder due to reduced levels and activity of factor XIII (FXIII) and characterized by hemorrhagic diathesis frequently associated with spontaneous abortions and defective wound healing. Factor XIII deficiency is one of the most rare coagulation factor deficiencies.
Most common symptoms of CONGENITAL FACTOR XIII DEFICIENCY
- Bruising susceptibility
- Abnormal bleeding
- Ecchymosis
- Poor wound healing
- Prolonged bleeding after surgery
More info about CONGENITAL FACTOR XIII DEFICIENCY
FACTOR XIII, A SUBUNIT, DEFICIENCY OF
Description
Factor XIII deficiency is an autosomal recessive hematologic disorder characterized by increased bleeding and poor wound healing. Most cases of congenital factor XIII deficiency result from mutation in the A subunit (Kangsadalampai et al., 1999).{21,22:Ichinose et al. (1996, 2000)} proposed a classification of factor XIII deficiency: XIIIA deficiency (formerly 'type II' F13 deficiency) and XIIIB deficiency (formerly 'type I' F13 deficiency), as well as a possible combined deficiency of the 2.
Most common symptoms of FACTOR XIII, A SUBUNIT, DEFICIENCY OF
- Bruising susceptibility
- Abnormal bleeding
- Decreased testicular size
- Epistaxis
- Spontaneous abortion
More info about FACTOR XIII, A SUBUNIT, DEFICIENCY OF
SOURCES: OMIM
Search interest in F13B
Potential gene panels for F13B gene
Factor XIII Deficiency Panel
United Kingdom.
By Sheffield Diagnostic Genetics Service Sheffield Children's NHS Foundation Trust Factor XIII Deficiency that also includes the following genes: F13A1 F13B
More info about this panel United Kingdom.
F13B. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the F13B gene.
More info about this panel Spain.
Factor XIII deficiency (sequence analysis of F13B gene) Panel
Portugal.
By CGC Genetics
This panel specifically test the F13B gene.
More info about this panel Portugal.
Bleeding Disorders Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Bleeding Disorders Sequencing Panel with CNV Detection that also includes the following genes: RUNX1 TBXA2R TBXAS1 VWF WAS ADAMTS13 ABCG5 ABCG8 GP6 HPS3
More info about this panel United States.
Coagulation Factor Deficiency Sequencing Panel with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics Coagulation Factor Deficiency Sequencing Panel with CNV Detection that also includes the following genes: VWF MCFD2 VKORC1 F10 F11 F12 F13A1 F13B F2 F5
More info about this panel United States.
Congenital Factor XIII Deficiency via F13B Gene Sequencing with CNV Detection Panel
United States.
By PreventionGenetics PreventionGenetics
This panel specifically test the F13B gene.
More info about this panel United States.
Factor XIIIB deficiency Panel
Germany.
By Centogene AG - the Rare Disease Company
This panel specifically test the F13B gene.
More info about this panel Germany.
F13A1 & F13B gene analysis Panel
United Kingdom.
By Molecular Haemostasis & Thrombosis GSTS Pathology - Guy's and St. Thomas' NHS Foundation Trust F13A1 & F13B gene analysis that also includes the following genes: F13A1 F13B
More info about this panel United Kingdom.
F13B Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the F13B gene.
More info about this panel United States.
Comprehensive Hematology Panel Panel
Finland.
By Blueprint Genetics Comprehensive Hematology Panel that also includes the following genes: RHAG RIT1 RPL11 RPL15 RPL35A RPL5 RPS10 RPS19 RPS24 RPS26
More info about this panel Finland.
Factor XIII, deficiency Panel
Spain.
By Bioarray
This panel specifically test the F13B gene.
More info about this panel Spain.
FACTOR XIII DEFICIENCY Panel
Spain.
By Laboratorio de Genetica Clinica SL FACTOR XIII DEFICIENCY that also includes the following genes: F13A1 F13B
More info about this panel Spain.
Factor XIIIB Deficiency , Sequencing F13B Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the F13B gene.
More info about this panel Spain.
Thrombophilia due to Factor XIII Deficiency , Massive Sequencing (NGS) F13A1, F13B Genes Panel
Spain.
By Reference Laboratory Genetics Thrombophilia due to Factor XIII Deficiency , Massive Sequencing (NGS) F13A1, F13B Genes that also includes the following genes: F13A1 F13B
More info about this panel Spain.
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