Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f
Description
Autosomal recessive limb-girdle muscular dystrophy type 2F (LGMD2F) is a subtype of autosomal recessive limb-girdle muscular dystrophy characterized by a variable age of onset of progressive weakness and wasting of the proximal skeletal muscles of the shoulder and pelvic girdles, frequently associated with progressive respiratory muscle impairment and cardiomyopathy. Calf hypertrophy, muscle cramps and elevated serum creatine kinase levels are also observed. Neuropsychomotor development is usually normal.
Genes related to Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f
- SGCD
Clinical Features
Top most frequent phenotypes and symptoms related to Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f
- Respiratory insufficiency
- Elevated serum creatine phosphokinase
- Difficulty walking
- Proximal muscle weakness
- Myalgia
- Hypertrophic cardiomyopathy
- Facial palsy
- Muscular dystrophy
- Dilated cardiomyopathy
- Falls
And another 14 symptoms. If you need more information about this disease we can help you.
Incidence and onset information
— Based on the latest data available AUTOSOMAL RECESSIVE LIMB-GIRDLE MUSCULAR DYSTROPHY TYPE 2F have a estimated prevalence of 0.3 per 100k worldwide.— No data available about the known clinical features onset.
Alternative names
Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f Is also known as delta-sarcoglycanopathy, limb-girdle muscular dystrophy due to delta-sarcoglycan deficiency, lgmd2f, muscular dystrophy, limb-girdle, type 2f.
Researches and researchers
Doctors, researchs, and experts related to Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f extracted from public data.
Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f Experts map
Current Researchs and researchers
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PADOVA — Dr Dorianna SANDONA'
Investigator of research project
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Institution/s:
— Università degli Studi di Padova- Polo A.Vallisneri -
Research area/topic::
Small molecule-based therapy for sarcoglycanopathies. Assessment of efficacy and tolerability in novel animal models
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Institution/s:
Autosomal Recessive Limb-girdle Muscular Dystrophy Type 2f Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
Limb Girdle Muscular Dystrophy Advanced Evaluation.
By Athena Diagnostics Inc (United States).
SGCA, SGCB, SGCD, SGCG, TCAP, MYOT, TTN, CAPN3, DNAJB6, CAV3, TRIM32, FKRP, POMGNT1, POMT2, TRAPPC11, DAG1, ANO5, DES, DYSF, FKTN , (...)
View the complete list with 3 more genes
Specificity
5 %
Genes
100 % |
Muscular Dystrophy Advanced Evaluation.
By Athena Diagnostics Inc (United States).
SGCA, SGCB, SGCD, SGCG, TCAP, MYOT, TTN, CCDC78, CAPN3, DNAJB6, CAV3, TRIM32, SYNE2, SYNE1, FKRP, POMGNT1, POMT2, TRAPPC11, DAG1, ANO5 , (...)
View the complete list with 13 more genes
Specificity
4 %
Genes
100 % |
Comprehensive Cardiac Panel.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center (United States).
RIT1, RYR2, SCN1B, SCN2B, SCN4B, SCN5A, SGCD, SLC22A5, BRAF, SNTA1, SOS1, TAZ, TCAP, TGFB3, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TTN , (...)
View the complete list with 86 more genes
Specificity
1 %
Genes
100 % |
Neuromuscular Disorders Panel.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center (United States).
RYR1, BIN1, SCN4A, SGCA, SGCB, SGCD, SGCE, SGCG, SLC25A4, SUCLA2, SUCLG1, TWNK, TCAP, TIA1, TK2, TNNI2, TNNT1, TPM2, TPM3, MYOT , (...)
View the complete list with 124 more genes
Specificity
1 %
Genes
100 % |
Dilated & Arrhythmogenic Cardiomyopathies Panel.
By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center (United States).
RYR2, SCN5A, SGCD, TAZ, TCAP, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TTN, TTR, VCL, MYOZ2, PRDM16, ACTC1, CASQ2, LDB3, ACTN2, NEBL , (...)
View the complete list with 31 more genes
Specificity
2 %
Genes
100 % |
Dilated cardiomyopathy - full panel.
By CHEO Genetics Diagnostic Laboratory Children's Hospital of Eastern Ontario (Canada).
SGCD, TAZ, TCAP, TNNC1, TNNI3, TNNT2, TPM1, TTN, VCL, ACTC1, LDB3, ACTN2, CSRP3, CTF1, RBM20, DES, NEXN, EMD, ABCC9, LAMP2 , (...)
View the complete list with 5 more genes
Specificity
4 %
Genes
100 % |
Dilated cardiomyopathy - familial variant analysis.
By CHEO Genetics Diagnostic Laboratory Children's Hospital of Eastern Ontario (Canada).
SGCD, TAZ, TCAP, TNNC1, TNNI3, TNNT2, TPM1, TTN, VCL, ACTC1, LDB3, ACTN2, CSRP3, CTF1, RBM20, DES, NEXN, EMD, ABCC9, LAMP2 , (...)
View the complete list with 5 more genes
Specificity
4 %
Genes
100 % |
Pan-cardiomyopathy panel.
By CHEO Genetics Diagnostic Laboratory Children's Hospital of Eastern Ontario (Canada).
RYR2, SGCD, TAZ, TCAP, TNNC1, TNNI3, TNNT2, TPM1, TTN, TTR, VCL, MYOZ2, ACTC1, CASQ2, CAV3, LDB3, ANKRD1, MYLK2, ACTN2, CRYAB , (...)
View the complete list with 25 more genes
Specificity
3 %
Genes
100 % |
You can get up to 138 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
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