Iga Nephropathy, Susceptibility To, 1; Igan1
Description
End-stage renal disease (ESRD) is a major public health problem, affecting 1 in 1,000 individuals and with an annual death rate of 20% despite dialysis treatment. IgA nephropathy (IgAN) is the most common form of glomerulonephritis, a principal cause of ESRD worldwide, affecting up to 1.3% of the population. Kidneys of patients with IgA nephropathy show deposits of IgA-containing immune complexes with proliferation of the glomerular mesangium. Typical clinical features include onset before age 40 with hematuria and proteinuria, and episodes of gross hematuria following mucosal infections are common; 30% of patients develop progressive renal failure. Although not generally considered a hereditary disease, striking ethnic variation in prevalence (Julian et al., 1985; D'Amico, 1987) and familial clustering (Scolari et al., 1999), along with subclinical renal abnormalities among relatives of cases, suggest a genetic component (Gharavi et al., 2000).
Clinical Features
Top most frequent phenotypes and symptoms related to Iga Nephropathy, Susceptibility To, 1; Igan1
- Neoplasm
- Hypertension
- Renal insufficiency
- Arthralgia
- Proteinuria
- Abnormality of the kidney
- Respiratory tract infection
- Stage 5 chronic kidney disease
- Cirrhosis
- Nephropathy
And another 11 symptoms. If you need more information about this disease we can help you.
Incidence and onset information
— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)— No data available about the known clinical features onset.
Alternative names
Iga Nephropathy, Susceptibility To, 1; Igan1 Is also known as igan, nephritis, iga type, berger disease.
Researches and researchers
Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.Sources and references
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